Clinical trials: Pregnancy - Prenatal Testing
Pregnancy - Prenatal Testing
GRAPE-GDM Prospective Comperative Trial - Grape Juice as a Replacement Drink for Gestational Diabetes Screening
Study Type: Observational, prospective, multicenter comparative study Primary Purpose: The goal of this study is to evaluate whether grape juice can serve as an effective alternative to the standard 50g glucola drink for…
- Trial name
- GRAPE-GDM (NCT07323901)
- Testing
- Participants will consume 500 ml of commercially available grape juice which contains 50g of sugar, serving as an alternative glucose load.
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Chlamydia Trachomatis Infection, Neonatal Infection
Antenatal Chlamydia Trachomatis and Neisseria Gonorrhoeae Testing to Prevent Adverse Neonatal Consequences
To assess the effectiveness of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing and treatment during pregnancy to reduce adverse pregnancy and birth outcomes compared to the standard of care (treatment based on…
- Conditions
- Chlamydia Trachomatis Infection, Neonatal Infection, Preterm Birth, Gonorrhea
- Trial name
- NCT04955717
- Testing
- Chlamydia trachomatis and Neisseria gonorrhoeae screening using the GeneXpert
- Where
- 2 sites in United States, Botswana
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pregnancy Related
Cell-Based Noninvasive Prenatal Testing
The purpose of the overall study is to develop improved methods for recovery and analysis of fetal cells from the mother's blood in order to develop clinically useful forms of cell-based, diagnostic, noninvasive prenatal testing…
- Trial name
- NIPT (NCT05245266)
- Testing
- Redraw for analysis of blood samples from healthy pregnant women
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Luna Genetics
Pregnancy, Maternal Anxiety
Music Listening During NST Monitoring
This study evaluated whether listening to music during routine non-stress test (NST) monitoring affects fetal parameters and maternal psychological outcomes.
- Conditions
- Pregnancy, Maternal Anxiety, Fetal Well-Being
- Trial name
- NCT07414641
- Testing
- Music Listening During NST
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Herpes Simplex, Pregnancy
A Study of HSV Testing Among Pregnant Women
The objective of the study is to evaluate the acceptance and effect of type- specific HSV serologic testing of pregnant women on sexual behavior at the end of pregnancy.
- Trial name
- NCT00194415
- Testing
- Safer-sex counseling, Type specific serologic HSV testing
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Washington
Maternal Stress, Fetal Well-Being
The Effect of Watching Cat Videos on Non-Stress Test Results And Stress Parameters in Pregnant Women
Pregnancy is a period in which women are physiologically and psychologically vulnerable, and the stress experienced can affect both maternal mental health and fetal well-being.
- Trial name
- NCT07332039
- Testing
- Group watching cat videos, Non-Video Watching Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy
Advanced Fetal Imaging - Phase II
The goal of Advanced Fetal Imaging - Phase II is to advance fetal MRI imaging by designing MRI coils specifically for pregnant women and testing recently developed MRI image acquisition techniques.
- Trial name
- NCT02840019
- Testing
- Investigational MRI coil designed for pregnant women, MRI Scan
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety, Fetal Distress
Music Therapy on High Risk Pregnant Women of Non-Stress Test
Non-stress testing (NST) is one of the most commonly used methods to assess fetal health in the prenatal period because it is an easily interpreted, non-invasive, painless, and short-term diagnostic method.
- Conditions
- Anxiety, Fetal Distress, Music
- Trial name
- NCT04986475
- Testing
- Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Prenatal Education
The Effect of Mother's Anxiety, Fear and Prenatal Connection in the Prenatal Education Given to Pregnant Women Via Podcast During the Non-stress Test
This study was planned to determine the effect of prenatal education given via podcast to nulliparous pregnant women who applied to the Non-Stress Test Polyclinic of the University of Health Sciences, Istanbul Bagcilar Training…
- Trial name
- NCT06313723
- Testing
- Prenatal education management delivered via podcast
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- YASEMİN AYDIN KARTAL
Smoking Cessation, Pregnancy Related
PRAMS: Peer-support To Reduce Antenatal Maternal Smoking
The goal of this feasibility is test the feasibility of conducting a randomised trial of the use of an online peer support group to promote smoking cessation and enhance sustained abstinence for women who smoke in pregnancy.
- Trial name
- PRAMS (NCT06595199)
- Testing
- Online peer support
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- King's College London
Pregnancy Related
Cell- Based Noninvasive Prenatal Testing (NIPT): Single Cell Prenatal Diagnosis (SCPD)
The purpose of the overall study is to develop improved methods for recovery of fetal cells from the mother's blood in order to develop a clinically useful form of cell-based, diagnostic, noninvasive prenatal testing (NIPT).
- Trial name
- NIPT & SCPD (NCT05076734)
- Testing
- Redraw for analysis of blood samples from healthy pregnant women
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Luna Genetics
Pregnancy
Assessment of Women's Insight and Understanding of Down's Syndrome Screening by Non-invasive Prenatal Testing (NIPT) During Their First Ultrasound
Down's syndrome is the leading cause for mental retardation in France. Screening for this chromosomal abnormality is systematically proposed during pregnancy.
- Trial name
- DEPIST21 (NCT03549286)
- Testing
- Questionnaire passation
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Trisomy 13, Trisomy 18
High Risk Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our proprietary algorithm method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278874
- Where
- 4 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Pre-Eclampsia, Placenta Diseases
Trial of Early Screening Test for Pre-eclampsia and Growth Restriction
A study of aspirin use in pregnancy to prevent high blood pressure and growth restriction of the fetus
- Conditions
- Pre-Eclampsia, Placenta Diseases, Eclampsia Preeclampsia, Fetal Growth Retardation
- Trial name
- TEST (NCT03674606)
- Testing
- Low dose aspirin
- Where
- 2 sites in Ireland
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Preeclampsia, Eclampsia
uChek Pilot Study for Urinalysis in the Antenatal Care Setting
A prospective observational study to test the feasibility of smartphone enabled uChek urinalysis device to detect biomarkers (protein, microalbumin and protein:creatine ratio) in urine, indicative of preeclampsia/eclampsia at…
- Conditions
- Preeclampsia, Eclampsia, Pregnancy, Proteinuria
- Trial name
- uChekBangla (NCT02256995)
- Testing
- uChek
- Where
- Bangladesh
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Maternova Research
Pregnancy - Prenatal Testing
The Effect of Using Nature Sounds and Virtual Reality During the Non-Stress Test
The aim of this study is to examine the effect of using nature sounds and virtual reality during the non-stress test on fetal well-being, maternal anxiety, comfort, and satisfaction.
- Trial name
- NCT07512999
- Testing
- Virtual Reality, Nature sounds, Control
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Amasya University
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Trisomy 13, Trisomy 18
Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our new NATUS diagnostic method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278536
- Where
- 8 sites in United States, India and 1 more
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.