Clinical trials: Pregnancy-Induced Hypertension in Postpartum
Hypertensive Disorders of Pregnancy (HDP), Hypertension, Pregnancy Induced
Community Support and Mobile Apps to Help Black Women Control High Blood Pressure After Pregnancy
The goal of this randomized clinical trial is to evaluate the effectiveness of a collaborative care intervention, consisting of remote blood pressure monitoring and support from community health workers, in improving blood…
- Conditions
- Hypertensive Disorders of Pregnancy (HDP), Hypertension, Pregnancy Induced, Severe Maternal Morbidity, Postpartum Hypertension
- Trial name
- PRIME CARE (NCT07606027)
- Testing
- Collaborative care, Standard of Care (SOC)
- Volunteers
- 404 people
- Sponsor
- University of Nebraska
Preeclampsia, Gestational Hypertension
Exploring the Effect of Discharge Education, Blood Pressure Cuffs, and Postpartum Bracelets to Improve Health Among Newly Diagnosed Gestational Hypertension and Preeclampsia Patients During the Postpartum Period.
This pilot, exploratory qualitative, descriptive study will examine whether standard postpartum discharge education, a free home blood pressure cuff, and an "At-Risk Postpartum" bracelet support self-management among postpartum…
- Conditions
- Preeclampsia, Gestational Hypertension, Postpartum
- Trial name
- NCT07807098
- Testing
- Education, Blood Pressure Cuff, and Visual Cue Bracelet
- Volunteers
- 40 people
- Sponsor
- Memorial Hermann Health System
Pregnancy-Associated Hypertension, Gestational Hypertension
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
High blood pressure during or after pregnancy (such as preeclampsia, gestational hypertension, eclampsia, or Hemolysis, Elevated Liver enzymes, and Low Platelet (HELLP) syndrome) raises a mother's risk of heart disease later in…
- Conditions
- Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia
- Trial name
- AW2H (NCT07778966)
- Testing
- Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- University of Alabama at Birmingham
Pre-Eclampsia, Gestational Hypertension
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
- Conditions
- Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03298802
- Testing
- Hydrochlorothiazide 50mg Tablet
- Where
- 2 sites in United States
- Volunteers
- 453 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Postpartum Hypertension (PPHT)
PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy
This randomized controlled trial compares two common medications, labetalol and extended-release nifedipine, to determine which is more effective at managing postpartum high blood pressure.
- Trial name
- PEACE (NCT06915792)
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Postpartum Hypertension Study
The purpose of this study is to assess which blood pressure medication (intravenous labetalol or oral nifedipine) works better in treating severely elevated blood pressure in women who have just delivered a baby.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
- Trial name
- NCT05139238
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Pre-eclampsia, Oocyte Donation
PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation.
- Conditions
- Pre-eclampsia, Oocyte Donation, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia; Mild
- Trial name
- PRIOR (NCT07263490)
- Where
- 6 sites in Denmark
- Volunteers
- 462 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Postpartum Period, Pregnancy
Enhancing Care & Outcomes for Patients During the First Postpartum Year
The United States is in the midst of a maternal mortality and morbidity crisis, with more than half of maternal deaths occurring within the first postpartum year.
- Conditions
- Postpartum Period, Pregnancy, Hypertension, Pregnancy Induced
- Trial name
- NCT06615076
- Testing
- Postpartum Visits
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Hypertension, Pregnancy-Induced, Postpartum Preeclampsia
Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
Investigators propose a comprehensive management program for postpartum patients with HDP who are at risk for severe maternal morbidity and mortality.
- Conditions
- Hypertension, Pregnancy-Induced, Postpartum Preeclampsia, Hypertension; Maternal
- Trial name
- NCT05849103
- Testing
- Blood Pressure Control Targets, Hypertension Management
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Vanderbilt University Medical Center
Postpartum Complication, Maternal Hypertension
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.
- Conditions
- Postpartum Complication, Maternal Hypertension, High Blood Pressure
- Trial name
- SCARPH (NCT05551104)
- Testing
- Oral Nifedipine, Oral Labetalol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Loma Linda University
Hypertension in Pregnancy, Postpartum Preeclampsia
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water…
- Trial name
- ACE (NCT05049616)
- Testing
- ACE Inhibitors and Diuretics, NIFEdipine ER
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hypertension, Pregnancy-Induced, Hypertension
Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines
To better understand postpartum blood pressure changes, the investigators are proposing a study to monitor blood pressure after delivery in 100 patients who the investigators expect to have normal blood pressure (i.e.
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication
- Trial name
- NCT06576544
- Testing
- BP Watch
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Diego
Hypertension in Pregnancy, Postpartum Preeclampsia
Rhode Island - Statewide Postpartum Hypertension Remote Surveillance
This is a hybrid type 1 non-inferiority implementation effectiveness trial among postpartum patients with hypertension (N=1536) that will test the hypothesis that RI-SPHERES (a technologically enabled collaborative care model) is…
- Conditions
- Hypertension in Pregnancy, Postpartum Preeclampsia, Postpartum Complication
- Trial name
- RI-SPHERES (NCT06842875)
- Testing
- RI-SPHERES, Standard self-measured blood pressure program
- Where
- 5 sites in United States
- Volunteers
- 1,536 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Postpartum Hypertension (PPHT)
Swiss Postpartum Hypertension Cohort
This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal…
- Trial name
- NCT04690660
- Testing
- Data collection for parameters of organ damage (cardiac and renal blood markers), Data collection for blood pressure (BP), Home-based blood pressure management (substudy)
- Where
- Switzerland
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Lasix for the Prevention of De Novo Postpartum Hypertension
Primary objective: To evaluate whether oral furosemide can help prevent de novo postpartum hypertension (new-onset high blood pressure after delivery) by reducing blood pressure after delivery in high-risk women.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Hypertension, Pregnancy-Induced, Hypertension
- Trial name
- LAPP (NCT04752475)
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Columbia University
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postpartum Preeclampsia, Hypertension in Pregnancy
Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial
Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.
- Trial name
- NCT05309460
- Testing
- Labetalol Oral Tablet, NIFEdipine ER
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Nebraska Methodist Health System
Pregnancy-Induced Hypertension in Postpartum, Postpartum Pre-Eclampsia
Management of Hypertension in the Early Postpartum: a Randomized Controlled Trial
In hypertensive mothers, it is common in clinical practice to substitute methyldopa for another medication, such as captopril, immediately after delivery, which may, as a consequence, cause a rebound effect or an initial lack of…
- Conditions
- Pregnancy-Induced Hypertension in Postpartum, Postpartum Pre-Eclampsia, Hypertension
- Trial name
- NCT04835233
- Testing
- Methyldopa 250 MG
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Federal University of Paraíba
Weight Loss, Postpartum Weight Retention
Postpartum Weight Loss for Women at Elevated Cardiovascular Risk
The aim of this study is to test the feasibility and effectiveness of a 16-week online behavioral weight loss program compared to usual care to promote weight loss in the postpartum period among women with cardiovascular risk…
- Conditions
- Weight Loss, Postpartum Weight Retention, Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
- Trial name
- EMPOWER-Mom (NCT04914819)
- Testing
- Online Behavioral Weight Loss Program, Virtual weigh-in
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Pennsylvania
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport