Clinical trials: Prehospital Emergency
Mass Casualty Incident Preparedness, Simulation-Based Medical Education
Mass-Casualty Incident - Prehospital Emergency Response
The goal of this study was to learn whether the MCIPHER memory aid could help first-year resident doctors manage a simulated mass-casualty incident.
- Trial name
- MCIPHER (NCT07838441)
- Testing
- Standard Mass-Casualty Incident Curriculum, MCIPHER mnemonic pre-brief, Tabletop Simulation
- Where
- United Arab Emirates
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Stroke
Prehospital Study at the Universitair Ziekenhuis Brussel II
Interventional prospective randomized open blinded end-point (PROBE) single-center clinical trial on the evaluation of the efficacy, safety, feasibility, reliability, and cost-effectiveness of in-ambulance telemedicine for…
- Trial name
- PreSSUB II (NCT02270541)
- Testing
- Telemedicine
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- Universitair Ziekenhuis Brussel
Stroke
Prehospital COOLing 1 (PreCOOL 1)
Elevated body temperature was shown to be associated with worse outcome in acute stroke patients. PreCOOL 1 aims to investigate efficacy, feasibility and safety of prehospital cooling with cold infusions in stroke patients.
- Trial name
- PreCOOL (NCT01669408)
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's solution
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Heidelberg
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Hemorrhagic Shock
Use of Blood and Plasma in Norwegian Physician-staffed Helicopter Emergency Medical System
The main objective of this study is to evaluate the use of RBC, FDP, WB in the treatment of exsanguinating patients by physician-staffed emergency medical services in Norway, with focus on prehospital transfusion complications…
- Trial name
- ProHEMS (NCT02784951)
- Testing
- Red blood cells (0Rh D-neg), Whole blood (O Rh D-neg K-neg), Freeze dried plasma (LyoPlas)
- Where
- 9 sites in Norway
- Volunteers
- 72 people
- Sponsor
- Haukeland University Hospital
Acute Stroke
Prehospital Telemedical Support in Acute Stroke
The aim of the study is to investigate the quality of prehospital emergency care in acute stroke, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644019
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- RWTH Aachen University
Acute Ischemic Stroke
Prehospital Response and Emergency Stroke Transport Optimisation
This study aims to develop and evaluate an innovative prehospital emergency transport system for patients with acute ischemic stroke to reduce delays in reperfusion treatment.
- Trial name
- PRESTO (NCT07892053)
- Testing
- Innovative pre-hospital emergency transport system for acute ischemic stroke
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Xuanwu Hospital, Beijing
Airway Management, Emergency
Prehospital Emergency Airway Research.
The creation of an airway registry will allow an improvement in the quality of care, the safety of critically ill patients in pre-hospital situations, and a reduction in morbidity and mortality related to airway management.
- Trial name
- PhEAR (NCT07289139)
- Where
- Spain
- Volunteers
- 4,300 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Prehospital Resuscitation, End-Tidal Carbon Dioxide
End-Tidal CO2 (ETCO2) Trends in Out-of-Hospital Cardiac Arrest
The investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2…
- Conditions
- Prehospital Resuscitation, End-Tidal Carbon Dioxide, Cardiac Arrest, Out-Of-Hospital, Prehospital Emergency Medical Services
- Trial name
- NCT07632430
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Office of the Medical Director for EMS in Oklahoma City and Tulsa
Communication Barriers
Video-Interpreting in Prehospital Emergency Medicine - Feasibility Study
50 responsive patients with language barriers will be included in this study. The prehospital emergency physician will start video-interpreting via a tablet.
- Trial name
- NCT06322004
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Respiratory Failure, Status Epilepticus
Pilot Simulation RCT of Telemedical Support for Paramedics
This study evaluates the impact of video communication via telemedicine on the quality of emergency care provided to children by paramedic teams supported by a remote physician in a simulated out-of-hospital setting.
- Conditions
- Respiratory Failure, Status Epilepticus, Status Asthmaticus, Cardiopulmonary Arrest
- Trial name
- NCT03742167
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston Medical Center
Emergencies, Prehospital
Synchronous Video (Telemedicine) Consulation in the Prehospital Setting
The study team aims to test connectivity metrics and follow patient outcomes using a new, innovative synchronous video technology in the prehospital setting in three distinct areas: 1. - 911 Calls 2.
- Conditions
- Emergencies, Prehospital, Telemedicine, Telehealth
- Trial name
- NCT03800316
- Testing
- Video Consultation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Mayo Clinic
Traumatic Brain Injury
Prehospital Traumatic Brain Injury
The aim of the study is to measure the effect of Finnish physician-staffed EMS unit treatment methods on traumatic brain injury (TBI) patient prognosis.
- Trial name
- NCT01454648
- Where
- Finland
- Volunteers
- 458 people
- Sponsor
- Tampere University Hospital
Acute Pain
Is There an Ideal Dose of Intravenous Fentanyl in the Prehospital Setting
In a previous study the investigators evaluated the apparent efficacy and safety of intravenous fentanyl administered by ambulance personnel and found that 58.4% (CI 56.4-60.4) out of 2348 prehospital patients treated with…
- Trial name
- NCT02914678
- Testing
- Fentanyl
- Volunteers
- 7,093 people
- Sponsor
- University of Aarhus
Ischemic Stroke
HEMS for Mechanical Thrombectomy
Elapsed time from the onset of stroke symptoms to the point of revascularization is the key determinant of the optimal outcome of acute ischemic stroke.
- Trial name
- NCT04834284
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Tampere University Hospital
Acute Illness, Acute Injury
Videoconferencing Between Ambulances and Physician at the Emergency Medical Dispatch Center, Effects on On-Site Patient Treatment and Patterns of Referral
The prehospital resources are limited. The emergency medical dispatch center (EMDC) is manned by qualified health care personnel around the clock.
- Trial name
- NCT02095067
- Testing
- Video consultation
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Acute Stroke
PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study
The purpose of this prospective study in acute ischemic stroke patients is to compare alarm-to-needle time during randomly allocated periods with and without availability of a specially staffed ambulance equipped with computed…
- Trial name
- PHANTOM-S (NCT01382862)
- Testing
- Stroke Emergency Mobile Unit (STEMO)
- Where
- Germany
- Volunteers
- 614 people
- Sponsor
- Charite University, Berlin, Germany
Trauma Injury, Haemorrhagic Shock
Prediction of Massive Transfusion in Trauma Patients
Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers.
- Conditions
- Trauma Injury, Haemorrhagic Shock, Bleeding, Emergencies
- Trial name
- MTP (NCT04561050)
- Testing
- Comparison of score performances (Overall performance, discrimination and calibration)
- Where
- Switzerland
- Volunteers
- 13,222 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Heart Arrest, Cardiac Arrest
Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
The investigators hypothesized that pre-arrival instructions would increase the likelihood of bystanders performing Cardiopulmonary Resuscitation (CPR).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiopulmonary Arrest, Out of Hospital Cardiac Arrest
- Trial name
- NCT02007499
- Testing
- Pre-Arrival Instructions
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Medical College of Wisconsin
Echocardiography, Acute Dyspnea
Live Stream of Prehospital Emergency Ultrasound in Patients With Acute Dyspnoea
Background: Acute dyspnoea is a common symptom in prehospital emergency medicine. As ultrasound gained in importance for diagnosis in patients with acute respiratory distress, it plays even a role in the prehospital setting.
- Trial name
- NCT04817488
- Testing
- Prehospital emergency ultrasound with tele-supervision, Prehospital emergency ultrasound without tele-supervision
- Where
- Austria
- Volunteers
- 350 people
- Sponsor
- Medical University of Vienna