Clinical trials: Premature
Hypothyroxinemia
Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia
In order to determine the efficacy and safety of thyroxine replacement, a randomized clinical trial of thyroxine supplementation for VLBW infant with hypothyroxinemia during the first month of age is conducted.
- Trial name
- NCT00565890
- Testing
- thyroxine
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tokyo Women's Medical University
Long QT Syndrome, Sinus Bradycardia
A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software
"Chang Gung ECG Abnormality Detection Software" is a is an artificial intelligence medical signal analysis software that detect whether patients have abnormal ECG signals of 14 diseases by static 12-lead ECG.
- Conditions
- Long QT Syndrome, Sinus Bradycardia, Sinus Tachycardia, Premature Atrial Complexes
- Trial name
- NCT05903313
- Testing
- Chang Gung ECG Abnormality Detection Software
- Where
- Taiwan
- Volunteers
- 4,306 people
- Sponsor
- Chang Gung Memorial Hospital
Retinopathy of Prematurity
Mother Milk as a Eye Drop & Premature Retinopathy
The aim of this study is to investigate the effect of using breast milk as eye drops on ROP (Retinopathy of prematurity) disease observed in less then 32 weeks gestational age preterm babies.
- Trial name
- NCT04883931
- Testing
- Normal Saline, Breast milk
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Baskent University
Preterm Birth
Comparison of Non-nutritive Suck (NNS) Measures to Clinical Estimates of Suck and Feeding Readiness in Preterm Infants
This is a research study to quantitatively assess the development of non-nutritive suck (NNS) and feeding readiness in preterm infants using a novel device, the NTrainer©, and to compare this with two clinical assessment tools…
- Trial name
- NCT01069731
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- KC BioMediX, Inc
Premature Birth
Neonatal Pulse Oximetry Sensor Study
To validate the SpO2 accuracy, bias, and precision of Medline's reprocessed pulse oximetry sensors as compared to SaO2 in arterial blood samples as assessed by CO-oximetry in neonates.
- Trial name
- NCT05250102
- Testing
- Pulse oximeter sensors
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Medline Industries
Premature Ejaculation
Trial of PED-1 in Male Patients With Premature Ejaculation
The purpose of this study is to evaluate whether PED-1 is more effective than Placebo in the treatment of premature ejaculation.
- Trial name
- NCT01439984
- Testing
- Clomipramine
- Where
- 5 sites in South Korea
- Volunteers
- 159 people
- Sponsor
- Symyoo
Preterm Birth
Prevention of Preterm Birth Using Cervical Pessary in Pregnant Women With Short Cervix in Twins
Placement of a vaginal pessary reduces significantly the rate of spontaneous preterm birth in pregnant women with twins and a short cervical length at 18-22 weeks scan.
- Trial name
- PECEP-TWINS (NCT01242410)
- Testing
- Silicon ring (Arabin Cervical Pessary)
- Where
- Spain
- Volunteers
- 137 people
- Sponsor
- Maternal-Infantil Vall d´Hebron Hospital
Preterm Birth
Can Cervical Stiffness in the Second Trimester Predict Preterm Birth in High-Risk Singleton Pregnancies?
Preterm birth (PTB), defined as delivery before 37 weeks gestation, is a common complication of pregnancy and affects up to 1 in 10 women in the UK.
- Trial name
- PRECISION (NCT05837390)
- Testing
- Cervical stiffness assessment, Cervical length measurement, Fetal fibronectin
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Liverpool
Bacterial Infections
Study Evaluate the PK Profile of Dalbavancin in Infants and Neonates Patients With Known or Suspected Bacterial Infection
The purpose of this study is to evaluate the Pharmacokinetic (PK) profile of a single intravenous (IV) infusion dose of dalbavancin, and to evaluate the safety and tolerability of a single dalbavancin IV infusion.
- Trial name
- NCT02688790
- Testing
- Dalbavancin
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- AbbVie
Pre-eclampsia, Oocyte Donation
PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation.
- Conditions
- Pre-eclampsia, Oocyte Donation, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia; Mild
- Trial name
- PRIOR (NCT07263490)
- Where
- 6 sites in Denmark
- Volunteers
- 462 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Postnatal Growth Disorder
Physiologic Approach to Sodium Supplementation in Premature Infants
Postnatal growth failure occurs in up to 50% of very low birth weight (VLBW, <1500 grams at birth) infants as assessed by discharge weight.
- Trial name
- Salt to Grow (NCT03889197)
- Testing
- Sodium supplementation guided by urine sodium concentration algorithm
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Indiana University
Congenital Heart Defect, Respiratory Distress Syndrome in Premature Infant
Neonatal Cardio-Pulmonary Outcome Measure
Neonatal Cardio-Pulmonary outcome measure (N-COM) will be used to assess the overall status of pulmonary and cardiac vascular system of neonates in Neonatal Intensive Care Unit (NICU).
- Trial name
- N-COM (NCT04324957)
- Testing
- Neonatal cardio-pulmonary outcome measure used to assess cardio-pulmonary status
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Asir John Samuel
Infant, Premature, Diseases
Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies
Alterations to microvascular blood flow in premature infants, are known to contribute to several major disease entities. The optically-measured tissue blood flow, to determine tissue perfusion that can be use to detect blood loss.
- Trial name
- NCT01982357
- Testing
- Laser Speckle Imaging and Diffuse Optical Spectroscopy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Anxiety, Amount of Breast Milk
The Effect of Virtual Reality Glasses on Anxiety Level and Breast Milk Amount
Pain, anxiety, nausea, vomiting, etc. In coping with symptoms, virtual reality glasses are recommended as a distraction application.
- Trial name
- NCT06153628
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Growth Disorders, Growth Failure
Is There a Microbiome Associated With Poor Growth in Preterm Infants?
This study evaluates the relationship between growth and stool microbiota in premature infants.
- Conditions
- Growth Disorders, Growth Failure, Prematurity
- Trial name
- NCT03761498
- Testing
- Caloric Requirement
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Texas Southwestern Medical Center
Premature
Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants
A comprehensive analysis of the impact of exogenous enteral DHA and ARA supplementation on lipid metabolism including the production of downstream derived mediators and how this impacts important biological pathways such as…
- Trial name
- NCT05380401
- Testing
- Enfamil® DHA & ARA Supplement for Special Dietary Use
- Where
- 7 sites in United States
- Volunteers
- 328 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Fetal Membranes, Premature Rupture
Safety and Efficacy Study of Intentional Delivery in Women With Preterm and Prelabour Rupture of the Membranes
Two-year multicentre randomized controlled parallel trial to compare intentional delivery and conservative management in pregnant women with preterm and prelabour rupture of membranes between 32 and 35 weeks.
- Trial name
- NCT00259519
- Testing
- Induction of delivery
- Where
- 11 sites in Canada
- Volunteers
- 152 people
- Sponsor
- University of Alberta
Schizophrenia, Physical Activity
Physical Exercise in Patients With Schizophrenia
Randomised clinical trial on a cohort of subjects with a diagnosis of schizophrenia of legal age, of both sexes, recruited in the mental health clinics of the Salamanca University Assistance Complex and who will be randomly…
- Conditions
- Schizophrenia, Physical Activity, Telomere Shortening, Premature Aging
- Trial name
- NCT05978921
- Testing
- Strength physical exercise programme, Normal life
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Salamanca
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Preterm Birth, Retinopathy of Prematurity
Vitamin A and Very Low Birthweight Babies (VitAL)
Vitamin A is important for the development of healthy eyes and lungs. Very low birth weight premature babies have low body stores of vitamin A and are prone to diseases of the eye and lungs.
- Trial name
- NCT00417404
- Testing
- Aquasol A
- Where
- 2 sites in United Kingdom
- Volunteers
- 94 people
- Sponsor
- Glasgow Royal Infirmary