Clinical trials: Premature Ventricular Complex
Premature Ventricular Contraction
Remote Magnetic Versus Manual Navigation-guided Ablation for Non-outflow Tract Premature Ventricular Contractions: a Prospective, Randomized, Controlled Trial
This prospective, randomized, controlled trial is designed to compare the safety and efficacy of remote magnetic navigation-guided ablation for ventricular premature complexes arising from non-outflow tracts with manual control…
- Trial name
- NCT04519112
- Testing
- Catheter Ablation
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Premature Ventricular Contraction
Shensongyangxin Capsule in the Treatment of Sinus Bradycardia With Premature Ventricular Contractions
The purpose of this study is to assess the effects of Chinese medicine Shansong Yangxin capsule for sinus bradycardia complicated with ventricular premature beats.
- Trial name
- SS-SBVPT (NCT01750775)
- Testing
- Shensong Yangxin capsule
- Where
- China
- Volunteers
- 330 people
- Sponsor
- kejiang Cao
Ventricular Arrhythmia
Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population
To evaluate the effectiveness and safety of catheter ablation of frequent symptomatic PVCs in the pediatric population as first-line therapy compared with antiarrhythmic drugs.
- Trial name
- RAS (NCT02772354)
- Testing
- Radiofrequency catheter ablation, Metoprolol, Verapamil
- Where
- 2 sites in Russia
- Volunteers
- 124 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Ventricular Premature Complexes
CBT for Premature Ventricular Contractions
The purpose of the present interdisciplinary research program is to develop and evaluate a disease-specific cognitive behavior therapy (CBT) protocol to increase quality of life (QoL) and reduce symptom burden in patients with…
- Trial name
- PVC-CBT (NCT05087238)
- Testing
- CBT
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Premature Ventricular Contraction
Urine Levels of Metanephrin and Normetanephrin in Patients With Frequent Ventricular Premature Complex
Enhanced automaticity process is the underlying mechanism for arrhythmias due to excess catecholamines. Catecholamines may increase in patients with PVC. Metabolites of catecholamines are metanephrine and normetanephrine.
- Trial name
- NCT03447002
- Testing
- 24 hours urine levels metanephrine and normetanephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- TC Erciyes University
Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation
A Study of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter
The purpose of this study is to assess the performance and safety of using the investigational catheter.
- Conditions
- Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- NCT05970120
- Testing
- NUVISION NAV Ultrasound Catheter
- Where
- 3 sites in Croatia, Israel and 1 more
- Volunteers
- 30 people
- Sponsor
- Biosense Webster, Inc.
Premature Ventricular Complexes, Ventricular Tachycardia (VT)
Transcutaneous Vagus Nerve Stimulation for Ventricular Arrhythmias
Ventricular arrhythmias are abnormal heart rhythms that arise from the bottom chambers of the heart. They can cause debilitating symptoms when they occur intermittently (these are called premature ventricular ectopics or PVCs)…
- Conditions
- Premature Ventricular Complexes, Ventricular Tachycardia (VT), Ventricular Arrhythmias
- Trial name
- TREAT-VT (NCT07026695)
- Testing
- transcutaenous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University College, London
Long QT Syndrome, Sinus Bradycardia
A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software
"Chang Gung ECG Abnormality Detection Software" is a is an artificial intelligence medical signal analysis software that detect whether patients have abnormal ECG signals of 14 diseases by static 12-lead ECG.
- Conditions
- Long QT Syndrome, Sinus Bradycardia, Sinus Tachycardia, Premature Atrial Complexes
- Trial name
- NCT05903313
- Testing
- Chang Gung ECG Abnormality Detection Software
- Where
- Taiwan
- Volunteers
- 4,306 people
- Sponsor
- Chang Gung Memorial Hospital
Ventricular Arrhythmia, Ventricular Tachycardia
IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry
This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular…
- Conditions
- Ventricular Arrhythmia, Ventricular Tachycardia, Premature Ventricular Contraction (PVC), Cardiomyopathy
- Trial name
- IVTCC (NCT04520347)
- Where
- 41 sites in United States, Canada and 5 more
- Volunteers
- 10,000 people
- Sponsor
- University of California, Los Angeles
Premature Ventricular Contractions
Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles
This randomized, prospective, parallel, single-blind, multicenter clinical trial investigates the efficacy and safety of intracardiac echocardiography (ICE)-guided catheter ablation versus pressure-sensing catheter ablation alone…
- Trial name
- NCT06898281
- Testing
- intracardiac echocardiography (ICE)-guided catheter ablation, Pressure-sensing catheter ablation alone
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shanghai Chest Hospital
Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies
Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)
Premature ventricular contractions (PVCs) coexist in patients with heart failure (HF) and LV dysfunction. Frequent PVCs have shown to induce a reversible cardiomyopathy (PVC-CM).
- Trial name
- PAPS (NCT03228823)
- Testing
- Radiofrequency ablation, Amiodarone (Antiarrhythmic drug)
- Where
- 11 sites in United States, Canada
- Volunteers
- 5 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Premature Ventricular Complexes
Optimal EGM Configuration for Morphology Discrimination
The study will be a prospective cohort study of 20 patients recruited from site's Defibrillator Clinic patient population who are followed at the site.
- Trial name
- SVT Morphology (NCT00888667)
- Testing
- Pacing interventions
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Abbott Medical Devices
Premature Ventricular Contraction
Efficacy and Safety of Sulcardine Sulfate Tablets in Patients With Premature Ventricular Contractions
Arrhythmia is a common disease that may be caused by various cardiovascular diseases. According to statistics, 500,000 people die of severe arrhythmia every year in China, In the United States, approximately 540,000 patients die…
- Trial name
- NCT01235156
- Where
- 2 sites in China
- Volunteers
- 36 people
- Sponsor
- Jiangsu Furui Pharmaceuticals Co., Ltd
Premature Ventricular Contraction, Ventricular Tachycardia
VIVO™ Accuracy Study
A multi-center study designed to assess the accuracy of VIVO™ in determining the location of a PVC/VT foci in comparison to an electroanatomical mapping system.
- Trial name
- NCT03340142
- Testing
- VIVO™
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Catheter Precision. Inc.
Atrial Fibrillation, Atrial Flutter
Risk Factors in Tachycardiomyopathy
Decision between rate control and rhythm control can be a challenge in clinical practice. While there is some guiding evidence, we still lack a comprehensive insight into different subgroups of patients that will benefit from a…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Ventricular Premature Complexes
- Trial name
- EMPATHY (NCT03418467)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Ventricular Tachycardia, Cardiomyopathy
Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia
Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation (ENCORE) for Treatment of Ventricular Tachycardia
- Conditions
- Ventricular Tachycardia, Cardiomyopathy, Premature Ventricular Contractions
- Trial name
- ENCORE-VT (NCT02919618)
- Testing
- stereotactic body radiotherapy (SBRT)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Washington University School of Medicine
Premature Ventricular Complexes
TAES for FPVCs: a Pragmatic, Randomized Controlled Trial
This prospective, randomized controlled trial aims to evaluate the efficacy and safety of Transcutaneous Auricular Vagus Nerve Stimulation (TAVNS) for patients with frequent premature ventricular coomplexes (FPVCs).
- Trial name
- NCT04415203
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (TAVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Ventricular Premature Complexes, Catheter Ablation
MANual vs. automatIC Local Activation Time Annotation for Guiding Premature Ventricular Complex Ablation
Current navigation systems incorporate algorithms for automatic identification of local activation time (LAT). However, data about their utility and accuracy in premature ventricular complex (PVC) ablation procedures are scarce.
- Trial name
- MANIaC-PVC (NCT03340922)
- Testing
- Automatic annotation of LAT (WF-method), Manual annotation of LAT (M-method)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Centro Medico Teknon
Cardiac Arrhythmia, Atrial Fibrillation
Vektor vMap™ Clinical Validation Study
This is a retrospective, multi center clinical study collecting existing, de-identified subject data from medical records to be analyzed using an independent core laboratory to validate performance of a computational ECG mapping…
- Conditions
- Cardiac Arrhythmia, Atrial Fibrillation, Ventricular Arrythmia, Premature Ventricular Complexes Multiple
- Trial name
- NCT04559061
- Testing
- Cardiac ablation procedure
- Where
- 4 sites in United States
- Volunteers
- 225 people
- Sponsor
- Vektor Medical
ECG, Ventricular Arrhythmias
Hybrid Score to Predict OTVA-SOO in Patients with Wide Basal QRS
Outflow tract ventricular arrhythmia (OTVA) is the most common type of ventricular arrhythmia, and catheter ablation (CA) is the primary treatment option for patients experiencing symptoms.
- Conditions
- ECG, Ventricular Arrhythmias, Catheter Ablation
- Trial name
- NCT06602635
- Testing
- ECG and clinical score
- Where
- 6 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Centro Medico Teknon