Clinical trials: Preoperative
Anemia, Orthopedic Surgery
Intravenous Ferric Carboxymaltose (Ferinject) in Patients Undergoing Orthopaedic Surgery
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing hip or knee replacement
- Conditions
- Anemia, Orthopedic Surgery, High Risk of Blood Loss
- Trial name
- PRIVIRON (NCT01345968)
- Testing
- Ferinject 50 mg/ml, NaCl 0.9%
- Where
- 2 sites in Germany
- Volunteers
- 3 people
- Sponsor
- University Hospital Muenster
Cognitive Impairment
Preoperative Cognitive Screening in Older Surgical Patients Utility for Predicting Morbidity
The purpose of this work is to determine whether preoperative cognitive screening of patients over the age of 65 can be used as predictor of postoperative outcomes in patients undergoing lower extremity surgical procedures.
- Trial name
- NCT02598050
- Testing
- No Interventions as this is a observational study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea, Preoperative Evaluation
Systematic Screening for Obstructive Sleep Apnea During Preoperative Consultation Using AI-preoperative Agents
The goal of this observational study is to evaluate the feasibility of a systematic screening protocol for Obstructive Sleep Apnea (OSA) during preoperative anesthesia consultations in adults aged 50 and older undergoing elective…
- Trial name
- DASCA (NCT06779682)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Intelligence Anesthesia
Gastric Ultrasound, Gastric Ultrasound in Chronic Opioid Use (≥2 Weeks)
Does Pre-operative Gastric Ultrasound Influence Anaesthetic Decision-Making in Chronic Pain Patients? A Prospective Observational Cohort.
Gastric POCUS has been validated and shown to be an accurate diagnostic tool in both healthy individuals and medically complex patient populations.
- Conditions
- Gastric Ultrasound, Gastric Ultrasound in Chronic Opioid Use (≥2 Weeks), Gastric Ultrasound in Poorly Controlled Acute-on-chronic Pain, Gastric Ultrasound in Acute Opioid Administration Within 24 Hours Prior to the Procedure
- Trial name
- NCT07537582
- Where
- United Arab Emirates
- Volunteers
- 140 people
- Sponsor
- Danat Al Emarat Hospital
Gastric Cancer, Locally Advanced Malignant Neoplasm
Pre-Operative Or Peri-Operative Dox Regimen In Patients With Locally Advanced Resectable Gastric Cancer
Study design: Multicenter, randomized, open label phase II study Arm A: DOX 4 cycles - Surgery - Follow-up Arm B: DOX 2 cycles - Surgery - DOX 2 cycles - Follow-up Population: Male or female, 18-75 years of age, with a diagnosis…
- Trial name
- GastroDOC (NCT01876927)
- Testing
- DOX 4 cycles - Surgery, DOX 2 cycles - Surgery - DOX 2 cycles
- Where
- 20 sites in Italy
- Volunteers
- 106 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Urinary Bladder Cancer, Urinary Bladder Neoplasm
Neutrophils to Lymphocytes Ratio in Predicting the Response to BCG in Non-muscle Invasive Bladder Cancer
There is a relation between inflammatory cells and the prognosis of tumors (cancer colon, renal, liver, and urinary bladder). In this study, the investigators will link the Neutrophils to Lymphocytes ratio to the response to…
- Conditions
- Urinary Bladder Cancer, Urinary Bladder Neoplasm, BCG, Trans Urethral Resection of a Bladder Tumor
- Trial name
- NCT05946369
- Testing
- Neutrophil to lymphocyte ratio
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Ain Shams University
Renal Cell Carcinoma, Metastatic Disease
Pre-operative Administration of Sorafenib in Patients With Metastatic Renal Cell Carcinoma Undergoing Kidney Removal
The purpose of this study is to see if preoperative administration of Sorafenib reduces the size of the primary kidney tumour in patients with metastatic disease undergoing cytoreductive surgery.
- Trial name
- NCT00480389
- Testing
- Sorafenib
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University Health Network, Toronto
Cancer, Peritoneal Carcinomatosis
Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis
This is a prospective, phase II, non-randomized clinical imaging trial. Ga68-FAPI-46 is a novel radiotracer used in PET/CT imaging, targeting a protein of the tumor microenvironment called FAP (Fibroblast activation protein).
- Trial name
- FAPeCa (NCT06061874)
- Testing
- FAPI PET/CT
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Jules Bordet Institute
Depressed, Bariatric Surgery
The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression
The aim of this study is to observe the antidepressant effect of low-dose esketamine in obese patients with preoperative depression and seeking bariatric surgery.
- Trial name
- esketamine (NCT07179913)
- Testing
- Esketamine, Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Hospital of Jilin University
Pain, Postoperative, Surgery, Thoracic
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia
The aim of this study was to analyze a relationship between information support provided by an interdisciplinary team and the levels of anxiety, pain and satisfaction with postoperative analgesia in children and adolescents…
- Trial name
- NCT03488459
- Testing
- Routine preoperative information from a nurse, Additional information support from a psychologist
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Carpal Tunnel Surgery
Effectiveness of Medical Hypnosis in Virtual Reality on Preoperative Anxiety in Carpal Tunnel Surgery
Anxiety is a predominant factor among patients prior to surgery, particularly in the context of outpatient surgery, where the speed of care and same-day discharge can exacerbate this stress.
- Trial name
- NCT07083180
- Testing
- Recreative activity, Medical Hypnosis by virtual reality
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique MEGIVAL
Rectal Adenocarcinoma
Proteomic Approach Using Matrix-assisted Laser Desorption/Ionization Tandem Time-of-flight (MALDI-TOF/TOF) of Tumor Response in Rectal Carcinoma After Radiochemotherapy
Treatment for locally-advanced rectal adenocarcinoma includes preoperative radiochemotherapy before surgery with total mesorectal excision in order to reduce tumor infiltration, facilitate oncologic surgery and improve survival.
- Trial name
- PROTEORECTUM (NCT00855946)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Bordeaux
Preoperative Care, Colorectal Neoplasms
Assessing The Effectiveness of a Preoperative High Intensity Interval Training Programme In Older Colorectal Cancer Patients
The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by an increase in VO2peak, can be achieved within 31 days via HIT programme in a group of older, colorectal cancer patients.
- Conditions
- Preoperative Care, Colorectal Neoplasms, Aged, Exercise
- Trial name
- HITCa (NCT02188342)
- Testing
- HIT
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Nottingham
Breast Cancer
Paclitaxel + Trastuzumab + Pertuzumab as Pre-Op for Inflammatory BrCa
This research study is a Phase II clinical trial, which tests the safety and effectiveness of an investigational drug to learn whether the drug works in treating a specific cancer.
- Trial name
- NCT01796197
- Testing
- Trastuzumab, Pertuzumab, Paclitaxel
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Dana-Farber Cancer Institute
Head and Neck Cancer Squamous Cell Carcinoma
A Study Testing Emactinib Sulfate With Chemotherapy and Immunotherapy Before Surgery for Advanced Head and Neck Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of a novel combination therapy for locally advanced head and neck squamous cell carcinoma (HNSCC).
- Trial name
- NCT07457346
- Testing
- cisplatin+ nab-paclitaxel +adebrelimab + imaxitinib
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bladder Cancer, Interstitial Cystitis
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
The goal of this clinical trial research study is to evaluate the impact of preoperative oral immunonutrition (IN) on post-operative complications in patients undergoing a cystectomy.
- Conditions
- Bladder Cancer, Interstitial Cystitis, Painful Bladder Syndrome, Neurogenic Bladder
- Trial name
- INCyst (NCT05726786)
- Testing
- Immunonutrition
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Vaginal Hysterectomy, Postoperative Pain
Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Hysterectomy Via Vaginal Route
Hysterectomy performed through the vaginal route (HVR) is the preferred method for women seeking hysterectomy to address uterine concerns such as premalignant conditions and fibroids.
- Conditions
- Vaginal Hysterectomy, Postoperative Pain, vNOTES
- Trial name
- NCT06429605
- Testing
- duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Enhanced Recovery After Surgery, Gynecologic Disease
ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling
The Investigator propose a randomized trial that will assess whether participant involvement in pre-operative counseling for ERAS improves post-surgical pain scores.
- Trial name
- NCT04963751
- Testing
- Enhanced Recovery After Surgery (ERAS) Counseling to Patients, Enhanced Recovery After Surgery (ERAS) Counseling to Caregiver
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Abdominal Aortic Aneurysm
DynaCT in Preoperative Imaging Before Insertion of Stentgraft
Endovascular therapy of Aortic Aneurysms depends on good imaging facilities. A relatively new kind of x-ray equipment makes it possible to create computer tomography (CT) - like slice images in the operating room.
- Trial name
- DynaCT (NCT01146639)
- Testing
- DynaCT, Iodixanol
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Norwegian University of Science and Technology
Anterior Cruciate Ligament Rupture
Assessing the Efficacy of a Preoperative Navigation System in Anterior Cruciate Ligament Reconstruction
The ACL surgery robot features a preoperative navigation system that enhances the precision of bone tunnel placement. As the first dual-bundle reconstruction surgical robot developed in China, it integrates advanced technology to…
- Trial name
- NCT06858930
- Testing
- ACL footprint localization after preoperative navigation executed by robotic arm, ACL footprint localization after preoperative navigation executed by rmanual execution
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
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