Clinical trials: Preoperative Frailty
Femoral Fractures, Frailty
Preoperative Oral Nutrition And Outcomes In Frail Elderly Patients With Femur Fractures
The goal of this observational study is to learn whether preoperative oral nutrition support improves clinical outcomes in elderly patients with femur fractures who have a high frailty index.
- Conditions
- Femoral Fractures, Frailty, Malnutrition
- Trial name
- NCT07463352
- Testing
- Oral Nutritional Supplement (ONS)
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Duzce University
Frail Elderly Syndrome, Frailty
Efficacy of Preoperative Prehabilitation With a Home-based Supervised Exercise Program Against an Unsupervised Exercise Program for Frail Elderly Patients Undergoing Major Abdominal Surgery
Singapore's population is ageing, and more elderly people are undergoing elective major surgeries. Frail elderly experience greater functional decline and slower recovery in physical function after surgery compared to non-frail…
- Conditions
- Frail Elderly Syndrome, Frailty, Surgery
- Trial name
- HOME-PREPARE (NCT04892368)
- Testing
- Home-based supervised exercise program
- Where
- Singapore
- Volunteers
- 140 people
- Sponsor
- Singapore General Hospital
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Cancer Colorectal, Frailty
Digital Home-Based Prehabilitation Before Surgery
This clinical trial compares two different prehabilitation programs, with no organized prehabilitation, prior to major colorectal cancer surgery.
- Conditions
- Cancer Colorectal, Frailty, Surgery
- Trial name
- dHOPE (NCT06231576)
- Testing
- Prehabilitation
- Volunteers
- 140 people
- Sponsor
- Vestre Viken Hospital Trust
Geriatric Patients, Postoperative Complications
PREDICTING MINS WITH FRAILTY AND BIOMARKERS IN GERIATRIC SURGERY
The primary objective of this study is to develop and validate a machine learning model that integrates preoperative clinical data, biomarkers, and modified frailty indices (mFI-5) to accurately predict myocardial injury after…
- Conditions
- Geriatric Patients, Postoperative Complications, Frailty, Myocardial Ischemia
- Trial name
- NCT07566013
- Testing
- Preoperative Risk Assessment and Machine Learning Modeling
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- DİLEK KALAYCI
Frail Elderly Syndrome, Surgery
Development and Validation of a Preoperative Frailty Index Using Health Administrative Data
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard…
- Conditions
- Frail Elderly Syndrome, Surgery, Outcomes, Predictive Value of Tests
- Trial name
- NCT03354546
- Testing
- Frailty index
- Volunteers
- 511,285 people
- Sponsor
- Ottawa Hospital Research Institute
Frailty, Age Problem
Preoperative Frailty and Postoperative Prognosis in the Elderly After Major Surgeries
Elderly people often have comorbidities. However, there could be a big difference in their health status. Frailty is considered to be relevant to adverse outcomes.
- Conditions
- Frailty, Age Problem, Surgery
- Trial name
- NCT04655651
- Testing
- No intervention
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Peking Union Medical College Hospital
Cancer, Frailty
The Prehabilitation Study: Exercise Before Surgery to Improve Patient Function in People
The rapid aging of the population means that anesthesiologists care for elderly patients with increasing regularity. Although age is an independent predictor for adverse postoperative outcomes, significant outcome variation…
- Trial name
- NCT02934230
- Testing
- Prehabilitation Program
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Frailty
Effects of Preoperative Frailty on Postoperative Recovery
This study aims to evaluate frailty using Short Physical Performance Battery (SPPB) before surgery and find out how frailty affects short-term postoperative recovery after surgery using Quality of Recovery-15 (QOR-15)…
- Trial name
- NCT06185270
- Testing
- SPPB
- Volunteers
- 139 people
- Sponsor
- Seoul National University Hospital
Frail Elderly Syndrome
Home-based Prehabilitation for Elderly Patients
As a consequence of the increasing life expectancy hospitals are seeing a growing number of elderly patients undergoing elective surgery.
- Trial name
- TRAilty (NCT03964363)
- Testing
- Unsupervised home-based physical prehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Perioperative Risk Assessment
Frailty Assessment Reveals Cognitive Differences in ASA Classification: Anesthesiologists vs Large Language Models
The American Society of Anesthesiologists (ASA) Physical Status Classification System is widely used to assess perioperative risk, but it does not explicitly include frailty as a standardized variable.
- Trial name
- ASA-AI (NCT07399938)
- Testing
- Observational Assessment Only
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Colorectal Cancer
Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer
Fried Scale and its related scales were used to analyze the status and risk factors of preoperative frailty in elderly patients with colorectal cancer.
- Trial name
- NCT05879861
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Zunyi Medical College
Surgery
Preoperative Prehabilitation Program For Geriatric Patients in a Rural Healthcare Setting
The study will include patients who require elective major abdominal surgery for cancerous or non-cancerous conditions. The goal of the research is to assess the benefit of a prehabilitation program before surgery that includes…
- Trial name
- NCT06518369
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- The Guthrie Clinic
Frailty, Pre-operative Exercise
Home-based Exercise for Frail Individuals Prior to Cardiac Surgery
The goal of this quasi-experimental feasibility study is to determine if a home based exercise program, that is supported virtually by a physiotherapist, is feasible for frail adults that are waiting for cardiac surgery.
- Conditions
- Frailty, Pre-operative Exercise, Prehabilitation, Cardiac Surgery
- Trial name
- NCT05834556
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. Todd A Duhamel
Spine Degeneration, Spine Fusion
Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery
With the extended life expectancy of the Chinese population and improvements in surgery and anesthesia techniques, the number of aged patients undergoing surgery has been increasing annually.
- Conditions
- Spine Degeneration, Spine Fusion, Frailty Syndrome
- Trial name
- PRACTICE (NCT06140797)
- Testing
- Multimodal prehabilitation combined with perioperative ERAS care（PREERAS）
- Where
- 3 sites in China
- Volunteers
- 164 people
- Sponsor
- Xuanwu Hospital, Beijing
Frailty
Frailty in the Perioperative Period
The presence of frailty is associated with a high risk of complications in the perioperative period, increasing morbidity and mortality, hospital stay, and loss of quality of life.
- Trial name
- Frail-Negrin (NCT05893342)
- Testing
- Preoperative frailty diagnostic
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Postoperative Delirium (POD), Frailty at Older Adults
Preoperative Lymphocyte-to-Monocyte Ratio and Postoperative Delirium by Frailty Status in Older Surgical Patients
Both frailty and a reduced preoperative lymphocyte-to-monocyte ratio (LMR) are known risk factors for postoperative delirium (POD). However, whether the relationship between LMR and POD varies by frailty status remains unclear.
- Conditions
- Postoperative Delirium (POD), Frailty at Older Adults, Lymphocyte
- Trial name
- NCT07322744
- Where
- China
- Volunteers
- 6,475 people
- Sponsor
- Chinese PLA General Hospital
Bladder Cancer, Bladder Neoplasm
Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct)
A bicentric, open-label randomised controlled trial (RCT) is planned to investigate whether the use of fitness wristbands in a defined preoperative period prior to radical cystectomy leads to a preoperative increase in…
- Conditions
- Bladder Cancer, Bladder Neoplasm, Bladder Urothelial Carcinoma
- Trial name
- PreAct (NCT06416319)
- Testing
- Daily Activity Goal and Feedback
- Where
- 2 sites in Germany
- Volunteers
- 164 people
- Sponsor
- Universitätsmedizin Mannheim
Gynecologic Cancer, Frailty
Cognitive and Physical Frailty as Predictors of Decision Satisfaction in Geriatric Gynecologic Oncology
This prospective observational study aims to evaluate the association between preoperative cognitive function, measured by the Montreal Cognitive Assessment (MoCA), and physical frailty, assessed using the Clinical Frailty Scale…
- Conditions
- Gynecologic Cancer, Frailty, Cognitive Impairment, Geriatric Oncology
- Trial name
- GYNCOGFRAIL (NCT07085000)
- Testing
- No Intervention - Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir City Hospital
Coronary Arterial Disease (CAD), Fraility
Correlation of Euroscore-II, STS Risk Scoring Systems and Frailty Tests with Cardiac Histopathological Findings in Coronary Bypass Surgery
Various risk classification systems are used to predict postoperative mortality and morbidity development in cardiac surgery. Risk calculation with these systems is a guide in determining preoperative strategies, performing cost…
- Conditions
- Coronary Arterial Disease (CAD), Fraility, Histopathology, Cardiac Risk Factors
- Trial name
- NCT06784609
- Testing
- Coronary Artery Bypass Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital