Clinical trials: Preoperative Risk Assessment
Cervical Cancer
System to Evaluate the Risk of Lymph Node Metastasis Preoperatively in Cervical Cancer
The lymph node status is difficult to be assessed preoperatively, this study aimed to develop a scoring system for predicting the risk of LNM in cervical cancer patients before operation.
- Trial name
- NCT06032481
- Testing
- surgery
- Volunteers
- 426 people
- Sponsor
- Fujian Maternity and Child Health Hospital
Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v8
Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer
This phase II trial studies how well apalutamide and gonadotropin-releasing hormone analog with or without abiraterone acetate work in treating participants with prostate cancer prior to surgery.
- Conditions
- Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8
- Trial name
- NCT03279250
- Testing
- Abiraterone Acetate, Apalutamide, Gonadotropin-releasing Hormone Analog
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- M.D. Anderson Cancer Center
Morbid Obesity
GlideScope With EGRI Assessment in Obese Patients
BACKGROUND Unpredicted difficult tracheal intubation (DTI) with Macintosh laryngoscopy occurs frequently in obese patients. We investigated the incidence of DTI using the GlideScope® videolaryngoscope (GVL) with an algorithm…
- Trial name
- GLOBE (NCT02188979)
- Where
- Italy
- Volunteers
- 195 people
- Sponsor
- Università degli Studi di Brescia
Surgical Risk Assessment, Postoperative Mortality
Preoperative Cardiac Power Output and P-POSSUM Score
This study aims to investigate the relationship between preoperative Cardiac Power Output (CPO), which reflects the pumping capacity of the heart, and the P-POSSUM score, a widely used surgical risk assessment tool, in patients…
- Conditions
- Surgical Risk Assessment, Postoperative Mortality, Postoperative Morbidity
- Trial name
- NCT07454564
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Necmettin Erbakan University
Spine Degeneration, Spine Fusion
Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery
With the extended life expectancy of the Chinese population and improvements in surgery and anesthesia techniques, the number of aged patients undergoing surgery has been increasing annually.
- Conditions
- Spine Degeneration, Spine Fusion, Frailty Syndrome
- Trial name
- PRACTICE (NCT06140797)
- Testing
- Multimodal prehabilitation combined with perioperative ERAS care（PREERAS）
- Where
- 3 sites in China
- Volunteers
- 164 people
- Sponsor
- Xuanwu Hospital, Beijing
High-risk Prostate Cancer, Prostate Cancer
Ga-68-PSMA-11 in High-risk Prostate Cancer
This will be an open-label, single-arm, rater-blinded, multicenter, diagnostic phase 1/2 study to assess safety and diagnostic performance of Ga-68-PSMA-11 positron emission tomography / computer tomography (PET/CT) imaging to…
- Conditions
- High-risk Prostate Cancer, Prostate Cancer, Prostate Cancer Metastatic, Lymphnode Metastasis
- Trial name
- NCT03362359
- Testing
- Ga-68-PSMA-11
- Where
- 8 sites in Austria, Germany
- Volunteers
- 173 people
- Sponsor
- German Cancer Research Center
Lung Diseases, Obstructive, Postoperative Complications
Preoperative Diagnostic Tests for Pulmonary Risk Assessment in COPD
This prospective study intends to investigate the incidence of postoperative pulmonary complications (PPC) or in-hospital mortality in patients with COPD or at risk for COPD undergoing high-risk noncardiac major surgery and to…
- Trial name
- PredicT (NCT02566343)
- Where
- Germany
- Volunteers
- 365 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Frailty, Frailty in Older Adults
Comparison of Preoperative Frailty Assessment Tools
Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults.
- Conditions
- Frailty, Frailty in Older Adults, Frailty/Sarcopenia
- Trial name
- PREFAS (NCT06889545)
- Testing
- Assessment of frailty using multiple tools
- Where
- Germany
- Volunteers
- 584 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Frail Elderly Persons, Cardiac Surgery
A Study Protocol for Research Investigating How Geriatric Risk Assessment and Shared Decision-making Conversations Affect Treatment Decisions and Quality of Life in Patients Eligible for Open-heart Surgery.
The goal of this study is to determine whether intervention by the PRIME clinic influences cardiac treatment decisions, as well as patients quality of life and healthcare utilization.
- Trial name
- PRIME (NCT06616129)
- Testing
- Geriatric assessment, Shared decision-making conversation
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- University Medical Center Groningen
Coagulation Disorder, Blood, Prolonged APTT
External Multicenter Validation of the APTTO Model for Prolonged APTT Using Clot Waveform Analysis
Prolonged activated partial thromboplastin time (APTT) is a frequent laboratory finding that may reflect a broad spectrum of underlying conditions, ranging from benign laboratory abnormalities to clinically relevant hemostatic…
- Trial name
- APTTO-EXT (NCT07418099)
- Testing
- Clot waveform analysis-based risk stratification (APTTO models)
- Where
- 16 sites in Spain
- Volunteers
- 1,500 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Obstructive Sleep Apnea Risk Management, Postoperative Complications
OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia
Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide.
- Conditions
- Obstructive Sleep Apnea Risk Management, Postoperative Complications, Dental Caries Under General Anesthesia, Obstructive Sleep Apnea of Adult
- Trial name
- NCT06430957
- Testing
- The STOP-BANG questionnaire for determining OSA risk level., ASA recommended criteria for determining OSA risk level., Record of postoperative complications
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kırıkkale University
Surgery, Cardiovascular
BNP Evaluation Before Surgery Study: an Observational Study of Natriuretic Peptide Levels Prior to Surgery.
A prospective, multi-centre, observational study of preoperative natriuretic peptide testing for patients undergoing non-cardiac surgery conducted over four weeks.
- Trial name
- EPIC-2 (NCT04114032)
- Where
- South Africa
- Volunteers
- 174 people
- Sponsor
- University of Cape Town
Nausea, Postoperative, Vomiting, Postoperative
Evaluation of the Effect of APFEL Risk Score and Fasting Periods on Postoperative Nausea and/or Vomiting
This study, it is aimed to determine the effect of Apfel risk score and fasting times on postoperative nausea and vomiting (PONV).
- Conditions
- Nausea, Postoperative, Vomiting, Postoperative, APFEL RİSK SCORE
- Trial name
- NCT06022705
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people
- Sponsor
- Cukurova University
Preoperative Nutritional Status and the Postoperative Outcome
Preoperative Nutritional Assessment of The Patients Undergoing Major Gastrointestinal Surgery and Their Immediate Postoperative Outcome
It was a prospective observational study, where preoperative nutritional status and early postoperative complications <30 days (infectious or noninfectious) were studied.
- Trial name
- NCT04039035
- Where
- Nepal
- Volunteers
- 134 people
- Sponsor
- National Academy of Medical Sciences, Nepal
Prostate Cancer
Diagnostic Performance of PSMA PET/CT for Pre-operative Lymph Node Assessment in Intermediate and High-risk Non-metastasic Prostate Cancer (PREOP-PSMA ).
In France, prostate cancer is the most common cancer in men over 50 years of age (nearly 50,000 new cases per year) and is the second most common cause of cancer death in men (approximately 9,000 deaths per year).
- Trial name
- PREOP-PSMA (NCT04745871)
- Testing
- PSMA PET/CT
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Brest
Gastric Residual Volume, Aspiration Risk
Gastric Residual Volume and Aspiration Risk Following Intravenous Metoclopramide in Fasted Diabetic Patients Undergoing Elective Surgery
This study aimed to evaluate the effect of metoclopramide on preoperative gastric emptying in diabetic patients.
- Conditions
- Gastric Residual Volume, Aspiration Risk, Metoclopramide, Fasted Diabetic Patients
- Trial name
- NCT07519447
- Testing
- Metoclopramide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Patient Fall
Evaluation of Balance and Movement in Order to Prevent the Risk of Falling in the Post-operative Period
This study aims to identify, in patients undergoing hip and knee joint replacement, the functional evaluation tools predictive of the risk of falling upon admission to the orthopedic department and to correlate the results…
- Trial name
- NOCADINRIAB (NCT05879315)
- Testing
- Fall risk prevention in hospital
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Abdominal Surgery
Preoperative Nutritional Assessment for Predicting Complications Risk in Patients Undergoing Abdominal Surgery
Predictive Value of Various Nutritional Screening and Assesment Tools and a Surgery Scoring System (POSSUM Score) for Predicting Postoperative Complications in Patients Scheduled for Abdominal Surgery.
- Trial name
- NCT03719508
- Where
- Greece
- Volunteers
- 450 people
- Sponsor
- Evangelismos Hospital
Preoperative Risk Assessment
Preoperative Risk Assessment in the Elderly
PrepTAB aims to determine whether elderly patients are able to complete 4 preoperative risk assessment questionnaires within a web-based survey.
- Trial name
- PrepTAB (NCT04160234)
- Testing
- web-based questionnaires
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Hip Fractures, Albumin
Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations
Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality.
- Conditions
- Hip Fractures, Albumin, Fibrinogen, Scoring Systems
- Trial name
- NCT05272072
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Istanbul University