Clinical trials: Presbyacusis
Hearing Loss, Age-Related
Hearing-physical Activity Intervention
Background By 2050, approximately 2.5 billion people are expected to experience some degree of age-related hearing loss (ARHL). Greater ARHL is associated with decreased communication, reduced physical activity and social…
- Trial name
- NCT07071168
- Testing
- hearing-physical activity training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hearing Loss, Sensorineural
PC-Based Rehabilitation of Auditory Function
Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds.
- Trial name
- CINT (NCT00724347)
- Testing
- Consonant Identification Training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dementia, Hearing Loss
Evaluation of the Impact of Cochlear Implants on Cognition in Older Adults
The subjects will be age 65 years and older, with no upper limit of age range with hearing loss that are candidates for standard-of-care cochlear implant.
- Conditions
- Dementia, Hearing Loss, Presbycusis
- Trial name
- NCT02729402
- Testing
- Cognitive Testing
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Utah
Presbycusis
Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss
Hearing loss, especially for speech perception in the presence of noise, may lead older individuals to withdraw from social situations.
- Trial name
- NCT07192757
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hearing Loss, Hearing Impairment
HEARS Maryland: Extending Capacity for Affordable, Accessible Hearing Care Through Older Adult Peer Mentorship
This study aims to assess the effectiveness of a Community Health Worker (CHW) delivered hearing loss intervention program (HEARS) for older adults in Maryland in collaboration with community organizations.
- Conditions
- Hearing Loss, Hearing Impairment, Age Related Hearing Loss, Age-related Hearing Impairment
- Trial name
- HEARS MD (NCT07699146)
- Testing
- HEARS MD Device, HEARS MD Program
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Age-related Hearing Loss
Hearing Loss and Communication Needs in a Group Care Setting for Older Adults
The purpose of this study is to develop and test a multicomponent hearing care intervention for the PACE staff members in order to learn more about communication and engagement.
- Trial name
- NCT04659967
- Testing
- Virtual Training
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Age-related Hearing Loss, Hearing Loss, Sensorineural
A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing Aids
Background: Deafness is one of the nine potentially modifiable risk factors for dementia simulated by the Lancet dementia Prevention, intervention and Care Committee in 2017.
- Conditions
- Age-related Hearing Loss, Hearing Loss, Sensorineural, Hearing Aid, Cognitive Function Abnormal
- Trial name
- NCT05694039
- Testing
- Hearing Aids
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Normal Hearing
The RBANS-H in Older Adults With Normal Hearing or Age-related Hearing Loss
The present cross-sectional study aims to examine the cognitive capabilities of older adults, aged 50 to 89, with normal hearing or age-related hearing loss by means of the Repeatable Battery for the Assessment of…
- Trial name
- RBANS-H_ARHL (NCT03208608)
- Testing
- RBANS-H
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors)
Hearing Screening in Adults Over 50 Years Old
The goal of this single-arm quasi-experimental study is to evaluate the feasibility, effectiveness, and management of three different hearing screening methods in adults aged 50 years and older in the Czech Republic.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors), Hearing Loss, Bilateral or Unilateral, Presbyacusis
- Trial name
- HSA50+ (NCT06894927)
- Testing
- Screening HHIA questionnaire, Whispered voice test, Screening pure tone audiometry
- Where
- 2 sites in Czechia
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
Age-related Hearing Loss, Presbycusis
Genetic Study of Age Related Hearing Loss
Age-related hearing loss, or presbyacusis, is one of the most common chronically handicapped conditions for the elderly. Many factors including genetics, diet, diseases, drugs, socioeconomic factors and environmental variables…
- Trial name
- ARHL (NCT01732289)
- Testing
- genes
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Progesterone, Estrogens
Neural Changes in the Aging Auditory System
The purpose of this study was to determine the effects of hormone replacement therapy (HRT) on hearing in post-menopausal women.
- Conditions
- Progesterone, Estrogens, Hearing, Psychoacoustics
- Trial name
- NCT00264407
- Testing
- Hormone Replacement Therapy - HRT
- Where
- 2 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Frailty, Malnutrition
Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)
Background. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly.
- Conditions
- Frailty, Malnutrition, Anorexia, Presbycusis
- Trial name
- EDERE 2021 (NCT04923087)
- Testing
- Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hearing Loss, Presbycusis
Predicting Success With Hearing Aids
The primary complaint of individuals with hearing loss is difficulty understanding speech in the presence of background noise. Although hearing aids help individuals understand speech in background noise better, there is a high…
- Trial name
- NCT00371449
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Presbycusis, Frailty Syndrome
Study of the Association Between Presbycusis With the Incidence of Frailty
The objective of the project is to establish the association between presbycusis and the incidence of frailty in humans in order to establish hearing loss with age as another index for the diagnosis of frailty; As well as…
- Conditions
- Presbycusis, Frailty Syndrome, Oxidative Stress
- Trial name
- NCT04360109
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Presbyacusis
Development of a Battery of Audiological Tests for the Precision Diagnosis of Age-related Hearing Loss
Age-related hearing loss, or presbycusis, is caused by many genetic and environmental factors. Its prevalence poses a public health challenge of early identification and effective hearing aid treatment.
- Trial name
- AUDIOGENAGE (NCT05312983)
- Testing
- Audiological and vestibular tests, Blood sampling, neurocognitive self-questionnaire
- Where
- 2 sites in France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Age-related Hearing Loss, Cognitive Decline
Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing Loss
Background: Age-related hearing loss (ARHL) is a common and irreversible condition that has been recently associated with cognitive decline and dementia. Hence, if ARHL is treated earlier, the risk of dementia might decrease.
- Conditions
- Age-related Hearing Loss, Cognitive Decline, Loneliness, Social Isolation
- Trial name
- NCT06486285
- Testing
- Auditory-cognitive dual-task training (ACDT)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hearing Loss, Age-Related
Early Identification of Age-related Hearing Impairment
The need for future hearing rehabilitation is enormous. World Health Organization (WHO 2021) has estimated that by 2050, 2.5 billion people will have some degree of hearing loss, and 1/4 of them will require hearing…
- Trial name
- NCT06418321
- Testing
- Investigational device, Audiometer, Otomicroscopy
- Where
- 2 sites in Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Aalto University
Hearing Loss, Age-Related
Hearing for Communication and Resident Engagement
Amplification is a well-established, evidence-based front-line treatment for those with impaired communication secondary to Age Related Hearing Loss (ARHL).
- Trial name
- HearCARE (NCT04575051)
- Testing
- Consult Model, Engage Model
- Where
- United States
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Age-related Hearing Loss, Dementia
Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring Dementia
Against the backdrop of global population aging, age-related hearing loss (ARHL) has reached epidemic proportions and is increasingly recognized as an independent risk factor for cognitive decline and other major…
- Trial name
- AHEAD (NCT07608640)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital