Clinical trials: Prescription
Pain, Postoperative, Opioid Misuse
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.
- Conditions
- Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
- Trial name
- NCT05548582
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500 mg Tab, Ibuprofen 600 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Adherence to Personalized EBM Antihypertensive Drug Prescriptions for Patients With Hypertension and Comorbidities in Everyday Clinical Practice
Antihypertensive Therapy in Patients With Comorbidities
A retrospective analysis
- Trial name
- NCT04791046
- Testing
- antihypertensive therapy
- Where
- Russia
- Volunteers
- 100,000 people
- Sponsor
- Center of Personalized Medicine, Pirogova
Opioid-Use Disorder (OUD)
SafetyNet Program for Opioid Use Disorder (OUD)
The principal aim of this study is to determine whether a novel biopsychosocial intervention following opioid overdose (OD) affects 1) the frequency of secondary opioid OD events and 2) the proportion of individuals who remain…
- Trial name
- NCT04253782
- Testing
- Team Intervention
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Yale University
Acute Respiratory Infections
C Reactive Protein (CRP) Intervention to Reduce Inappropriate Antibiotic Prescriptions in the Primary Healthcare Setting
Many studies have showed that rapid point-of-care (POC) c-reactive protein (CRP) test can reduce inappropriate use of antibiotic at primary health care level.
- Trial name
- CRP (NCT01918579)
- Testing
- Patients will be tested by rapid POC CRP test
- Where
- Vietnam
- Volunteers
- 2,037 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Opioid Overdose
Incidence and Predictors of Opioid Overdose and Death Among Long-Term Users of Opioid Analgesics
Retrospective study to assess incidence and predictors of opioid abuse overdose and death associated with opioid overdose among patients prescribed opioid products in long-term use.
- Trial name
- NCT02662153
- Testing
- Observation only
- Where
- 4 sites in United States
- Volunteers
- 808,455 people
- Sponsor
- Member Companies of the Opioid PMR Consortium
Prescriptions, Elderly (people Aged 65 or More)
Inappropriate Prescribing in the Elderly
The management of pharmacotherapy in elderly patients is an increasingly critical aspect, as polypharmacy, combined with the pharmacokinetic and pharmacodynamic changes typical of aging, makes older adults more sensitive to the…
- Conditions
- Prescriptions, Elderly (people Aged 65 or More), Hospitalized, Prevalence
- Trial name
- STOPP&START (NCT06760728)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury
Insights Into the Continuous Renal Replacement Therapy to Critical Ill Patients
This is a multinational, prospective, observational study designed to characterize patient demographics, prescription parameters, and process measures of continuous renal replacement therapy (CRRT) in intensive care units (ICUs)…
- Conditions
- Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury, Renal Dialysis, Critical Illness
- Trial name
- iCRRT (NCT07365111)
- Testing
- continuous renal replacement therapy
- Where
- Canada
- Volunteers
- 100,000 people
- Sponsor
- University of Alberta
Chronic Pain, Behavior, Addictive
Health Outcomes From Opioid Therapy for Chronic Pain
Although the use of opioid medications has gained increasing acceptance as a treatment option for chronic pain, there is little empirical research concerning long-term outcomes with this patient population.
- Trial name
- NCT00495404
- Testing
- Physician Treatment Guidelines
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- US Department of Veterans Affairs
Alcohol Use Disorder
Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder
BACLOPHONE is a prospective multicenter cohort study, conducted in two nearby French regions (Hauts-de-France and Normandie). BACLOPHONE consists of the monthly phone-based monitoring of 792 patients during their first year of…
- Trial name
- BACLOPHONE (NCT02596763)
- Testing
- Baclofen
- Where
- 19 sites in France
- Volunteers
- 239 people
- Sponsor
- University Hospital, Lille
Cancer
Individually Tailored Training Prescriptions in Cancer Patients: The TOP Study
The TOP Study is a two-stage study on individually tailored endurance and resistance training prescriptions for breast and prostate cancer patients after the end of primary therapy in order to optimize training effects.
- Trial name
- TOP (NCT02883699)
- Testing
- Standard endurance training, Polarized endurance training, Standard resistance training
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- University Hospital Heidelberg
Stage IV Lung Cancer
Truthful Information on Chemotherapy and Its Impact on Chemotherapy at the End of Life
Patients with metastatic cancer have a substantial symptom burden and may receive aggressive care at the end of life. There is evidence that the use of chemotherapy near the end of life is not related to its likelihood of…
- Trial name
- HIPPOCRATE (NCT02606149)
- Testing
- Truthful information on chemotherapy risks, Standard of information
- Where
- France
- Volunteers
- 123 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pneumonia
Errors in Prescription Antibiotics in Ventilator-associated Pneumonia
The infection is a major risk to hospitalized patients, especially those admitted to the Intensive Care Unit (ICU) and an unfavorable factor in the outcome of critically ill patients, increasing costs and prolonging…
- Trial name
- NCT02074033
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Federal University of Uberlandia
Opioid-Related Disorders, Opiate Addiction
A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire
The purpose of this study is to evaluate the patient usability and reliability of the POMAQ survey to evaluate opioid misuse and abuse among adults with chronic moderate to severe pain, including patients who are opioid abusers…
- Conditions
- Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- POMAQ (NCT02660606)
- Testing
- Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Member Companies of the Opioid PMR Consortium
Prescription
The Third Survey of Prescription Pattern of Psychotropic Drugs in China
The investigators aimed to examine the psychotropic prescription pattern in China.
- Trial name
- NCT01668810
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Peking University
Obesity, Adolescent
mHealth Biometrics for Young People With Obesity (MOTIVATE- LOOP)
The investigators aim to undertake a feasibility randomised controlled trial (RCT) to investigate whether mHealth technology, allowing biometric informed feedback and coaching on exercise and PA, can be incorporated into the…
- Trial name
- MOTIVATE-L (NCT04854915)
- Testing
- LOOP + mHealth technology assisted exercise counselling, LOOP Only
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Gait, Medication Induced Gait Disturbances
BioButton Among Nursing Home Residents
This pilot study will explore the use of the BioIntellisense BioButton, a remote wearable multi-parameter monitor, to identify gait disturbances that occur as a side effect of polypharmacy.
- Trial name
- NCT06665685
- Testing
- BioButton Device, Providing Clinical Care with BioButton Device
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Charles Lin
Depression, Anxiety
More Individualized Care: Assessment and Recovery Through Engagement
The MI-CARE trial tests 12 months of telephone-based nurse care management for patients with depressive symptoms who take or have taken opioids at some time.
- Conditions
- Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
- Trial name
- MI-CARE (NCT05122676)
- Testing
- More Individualized Care: Assessment and Recovery through Engagement (MI-CARE)
- Where
- 2 sites in United States
- Volunteers
- 805 people
- Sponsor
- Kaiser Permanente
Cancer
Patients' Expectations About the Survival Benefits of Cancer Drugs Approved Based on Progression-Free Survival
This study of current or former cancer patients will evaluate whether communicating data on overall survival data in addition to information on progression-free improves the accuracy of cancer patients' expectations about the…
- Trial name
- NCT07731425
- Testing
- FDA explanation for progression-free survival (control), FDA explanation for progression-free survival with overall survival data, NCI explanation for progression-free survival
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- London School of Economics and Political Science
Acute Decompensated Heart Failure, Acute Myocardial Infarction
Using an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical Recommendations
Health literacy is the ability to access, understand, evaluate and apply information in order to communicate with health professionals and understand health instructions but also, promote, maintain and improve health throughout…
- Trial name
- ILIADE (NCT03951467)
- Testing
- Interventional educational toolkit specific to low Health Literacy patients, designed with patients and health professionals.
- Where
- 4 sites in France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Understanding of Medication Instructions, Recall of Medication Instructions
PictureRx: An Intervention to Reduce Latino Health Disparities (Supplement: Medical Icons)
Research shows that well-developed icons and other pictorials aid in the comprehension of medication information and are effective in improving patients' medication management.
- Trial name
- NCT01618461
- Testing
- Drug indication icons, Structured instructions
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- PictureRx, LLC
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