Clinical trials: Prescription
Plasma Cell Myeloma
Exercise Prescription for the Improvement of Quality of Life in Elderly Patients With Multiple Myeloma
This trial studies how well exercise prescription works in improving quality of life in elderly patients with multiple myeloma. Engaging and adhering to an exercise program may improve functional status and quality of life and…
- Trial name
- NCT04100044
- Testing
- Exercise Counseling, Exercise Intervention, Questionnaire administration
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Thomas Jefferson University
Naloxone
Increasing Naloxone Access for Persons Who Use Opioids
Deaths relating to opioid overdose have rapidly increased over the past two decades. Due to the serious public health concern of the opioid epidemic, federal agencies recommend employing various harm reduction interventions.
- Trial name
- NCT04303000
- Testing
- Opioid Overdose Education with Naloxone Distribution, Opioid Overdose Education
- Where
- 4 sites in United States
- Volunteers
- 111 people
- Sponsor
- University of Alabama at Birmingham
Opioid Use, Pain
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain…
- Conditions
- Opioid Use, Pain, Marijuana Use
- Trial name
- NCT04827992
- Testing
- Cannabis, Prescription Opioid Taper Support (POTS)
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhythmias
The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.
- Conditions
- Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1, Catecholaminergic Polymorphic Ventricular Tachycardia Type 2
- Trial name
- ACTIVELY (NCT06661278)
- Testing
- Exercise tolerance test, Physical activity & heart rate monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Dietary Modification
Penn State ProduceRx Feasibility Study
To provide "prescriptions" for weekly Community Supported Agriculture (CSA) boxes of fruits and vegetables to patients, accompanied by nutritional education (e.g.
- Trial name
- NCT02794818
- Testing
- Produce boxes with nutritional education
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Adult Patients Who Declare an Allergy to Penicillin During Anaesthetic Consultation Without Any Allergy Work up That Could Confirm This Declaration, Good Comprehension of French Language
Assessment of the Applicability and Acceptability of an Algorithm to Guide the Prescription of 1st and 2nd Generation Cephalosporins as Part of Intraoperative Antibiotic Prophylaxis in Patients With a Declared Allergy to Penicillin
According to the Centers for Disease Control and Prevention (CDC), a surgical site infection (SSI) is an infection that occurs after surgery at the site where the surgery was performed.
- Trial name
- PROPHYLAL (NCT06067919)
- Testing
- decision tree for the choice of intraoperative antibiotic prophylaxis
- Where
- France
- Volunteers
- 275 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Implementing Personalized Exercise Prescriptions Through Mobile Health in the Elderly Cancer Survivors
Cancer remains a vital public health concern in the U.S. Research evidence has shown that physical activity provides many physical and mental health benefits after cancer diagnosis and plays an important role in reducing…
- Trial name
- NCT05069519
- Testing
- Personalized Smartwatch, Facebook Health Education
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Minnesota
Patients at High Risk of Antibacterial Treatment Upon Admission
Impact of Prescription Quality, Infection Control and Antimicrobial Stewardship on Gut Microbiota Domination by Healthcare-Associated Pathogens
Extended-spectrum beta-lactamase producing Enterobacteriaceae (EPE), vancomycin-resistant enterococci (VRE) and Clostridium difficile have become a major threat to hospitalised patients worldwide.
- Trial name
- PILGRIM (NCT03765528)
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital of Cologne
Opioid-use Disorder, Overdose of Opiate
Patient Reported Outcomes for Opioid Use Disorder
The goal of the project is to build a clinical data research infrastructure that will begin to enhance capacity to use electronic health record (EHR) data and patient reported outcomes measures (PROs) to conduct opioid related…
- Conditions
- Opioid-use Disorder, Overdose of Opiate, Patient Participation
- Trial name
- NCT03985163
- Testing
- Patient Reported Outcomes Electronic Survey
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Yale University
Simulation Training, Anticoagulant Drugs
E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF
Atrial Fibrillation (AF) is the most common cardiac arrhythmia and the main cause of cardioembolic stroke. Oral Anticoagulation (OAC) has been shown to significantly prevent AF-related thromboembolism, however, despite convincing…
- Conditions
- Simulation Training, Anticoagulant Drugs, Elderly, Atrial Fibrillation
- Trial name
- SIM-AF (NCT03188211)
- Testing
- E-learning educational program, Control
- Where
- 20 sites in Italy
- Volunteers
- 247 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Overweight, Obesity
Fruit And Vegetable Or Recreation Prescriptions for UW-Madison Students
This research will use randomized controlled trial (RCT) methodology to assess the feasibility of a prescription for fruit/vegetable CSA shares or exercise by bikeshare on obesity-related outcomes.
- Trial name
- FAVORx (NCT02870322)
- Testing
- Fruit and Vegetable CSA Prescription, Bikeshare Prescription
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Retroperitoneal Sarcoma
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
This phase II trial studies how well a repeat or single liposomal bupivacaine injection (quadratus lumborum block) works in reducing opioid prescriptions after surgery in patients with retroperitoneal sarcoma.
- Trial name
- NCT04189783
- Testing
- Liposomal Bupivacaine, Quadratus Lumborum Block, Questionnaire Administration
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- M.D. Anderson Cancer Center
Acute Pain
Reducing Pain From Wisdom Molar Extractions
This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third…
- Trial name
- NCT05335070
- Testing
- Temporo-masseteric Nerve Block
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Frailty, Emergency Department Visit
Association Between Geriatric Frailty and Medication Related Problems in the Emergency Department to Help Clinical Pharmacists Prioritise Patients
The healthcare systems are under increasing pressure due to a rise in emergency consultations, staff shortages, an ageing population and rising costs.
- Conditions
- Frailty, Emergency Department Visit, Elderly, Drug Drug Interaction
- Trial name
- DISARMED (NCT07282379)
- Testing
- Pharmaceutical analysis based on the Electronic Patient Record
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Pharmacie des Hopitaux de l'Est Lemanique
Substance Use Disorder (SUD), Drug Overdose
Justice Community Overdose Innovation Network II TCU Hub
The current study proposes to use a Hybrid Type 3 implementation research strategy to: 1) Significantly enhance our understanding of public health outcomes [e.g., overdose incidents and substance-use (SU)-related Emergency…
- Conditions
- Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
- Trial name
- JCOIN II TCU (NCT07528846)
- Testing
- Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
- Where
- United States
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Bipolar I Disorder
An Observational Modified Prescription-event Monitoring Study of Asenapine (Sycrest)
This post-marketing Modified Prescription-Event Monitoring (M-PEM) safety study of asenapine (SYCREST®) is to be carried out by the Drug Safety Research Unit (DSRU) as part of the Risk Management Plan required by the Committee…
- Trial name
- NCT01765127
- Where
- United Kingdom
- Volunteers
- 122 people
- Sponsor
- Professor Saad Shakir
Rheumatoid Arthritis
IL-6 as a Biomarker for Personalized Treatment of PR
Several studies have shown the relevance of the IL6 level before treatment or after 6 months, as a predictive biomarker for the persistence of remission.
- Trial name
- REMISIX (NCT04779983)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Sepsis, Septic Shock
A STUDY BEFORE/AFTER THE IMPLEMENTATION OF AN ANTI-INFECTIOUS PRESCRIPTION AID
Anti-infective strategy is a major public health problem. This is a before-and-after study of an anti-infectious prescription tool with a comparison of mortality at 30 days (then 3 and 6 months) between the two inclusion phases…
- Trial name
- NCT05140213
- Testing
- Anti-infectious prescription support tool
- Where
- France
- Volunteers
- 371 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Type 2
Food As Medicine Study
The investigators are conducting a pre-randomized controlled trial to assess the effect of a 6 month Produce Prescription intervention for patients enrolled in Medicaid who experience consistently uncontrolled Hemoglobin A1c…
- Trial name
- NCT05407376
- Testing
- Produce prescription (weekly produce delivery)
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Kaiser Permanente
Opiate Overdose, Opioid-Related Disorders
Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care
This clinical trial aims to evaluate the pilot implementation of a machine-learning (ML)-driven clinical decision support (CDS) tool designed to predict opioid overdose risk within the electronic health record (EHR) system at UF…
- Conditions
- Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders
- Trial name
- DEMONSTRATE (NCT06810076)
- Testing
- Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
- Where
- United States
- Volunteers
- 674 people
- Sponsor
- University of Pittsburgh
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