Clinical trials: Prescription
Drug Overdose, Overdose of Beta-adrenergic Blocking Drug
Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
This trial investigates effects of a glucagon bolus injection on heart rate, blood pressure and cardiac output during beta-blocker-induced cardiodepression.
- Trial name
- GLUCAGON (NCT03533179)
- Testing
- Glucagon, Esmolol, Physiologic saline - glucagon dummy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Pregnant Women Participating in a Supervised Multicomponent Exercise Intervention
Impact of In-Person Versus Online Supervised Multicenter Multicomponent Prenatal Exercise Program on Maternal Physical Activity, Fitness, and Healthy Lifestyle
Many studies have been supporting the positive effects of an active lifestyle concerning the prevention and treatment of pregnancy-related complications and health problems, such as gestational diabetes, gestational hypertension…
- Trial name
- ActivePregnanc (NCT06954454)
- Testing
- prenatal physical exercise intervention
- Where
- 3 sites in Portugal
- Volunteers
- 250 people
- Sponsor
- Polytechnic University of Santarém
Overweight, Obesity
Effects of Nutrition Meal Replacement and Individualized Exercise Prescription on Type 2 Diabetes
This study evaluates the nutritional meal replacement and individualized exercise prescription intervention on overweight and obese type 2 diabetes mellitus.
- Conditions
- Overweight, Obesity, Type2 Diabetes
- Trial name
- NCT02984605
- Testing
- nutritional meal replacement
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Compliance, Emergency Department Aftercare
Using Point-of-Care Video Prescriptions to Improve Aftercare Following Discharge From a Pediatric Emergency Department
The goal of this project is to develop the content and delivery platform that electronically distributes mobile video discharge education for underserved populations and to demonstrate utilization, satisfaction, and improved…
- Conditions
- Compliance, Emergency Department Aftercare, Emergency Department Utilization
- Trial name
- NCT01543438
- Testing
- Video Prescription (additional education)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- healthEworks LLC
Prescription Stimulants, Expectations
The Role of Expectancy for Cognitive Enhancement in College Students Using Prescription Stimulants Nonmedically
We propose to evaluate the interaction between expectations of receiving stimulants, neurophysiological activity and enhancement of cognitive performance using fMRI.
- Conditions
- Prescription Stimulants, Expectations, Deception
- Trial name
- NCT04635826
- Testing
- Adderall 10Mg Tablet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Drug Overdose
A Usability Assessment of Naloxone by Community Members
This will be a usability trial to assess administration of naloxone via intramuscular, atomized intranasal, and nasal spray routes by nonmedical community members.
- Trial name
- NCT03309449
- Testing
- Syringe and needle, Intranasal mucosal atomization device, Nasal spray
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Caregiver, Patient
Patient and Caregiver Attitudes and Beliefs Regarding Prescription of Intranasal Naloxone Spray for Opioid Overdose
This trial studies the attitudes and beliefs of high risk patients and caregivers regarding the prescription of intranasal naloxone spray for opioid overdose.
- Trial name
- NCT04129138
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prescription Medication Understanding
Writing: a Factor That Can Influence Understanding of Prescriptions in the Geriatric Population
Understanding prescriptions is a key factor in the therapeutic education and compliance of elderly patients with multiple medications.
- Trial name
- ROSA (NCT06855017)
- Testing
- create a pillbox day
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Communicating Uncertainties Associated With the Benefits and Risks of New Cancer Drugs
This nationally representative randomized survey of US adults will evaluate the effect of using brief statements to communicate different sources of uncertainty about the benefits and harms of new cancer drugs on participants'…
- Trial name
- NCT06997185
- Testing
- Statement communicating uncertainty with a single arm trial, Statement communicating uncertainty with limited study duration, Statement communicating uncertainty with a limited study population
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Oral Surgeries
Evaluation of Pharmacogenomics Testing to Precision Prescriptions in Periodontal Patients
The different patients responses to medications vary from dose effectiveness to adverse drug reaction (ADRs). ADRs affect outpatient settings as it account for estimated 1 million emergency department visits and over 3.5 million…
- Trial name
- NCT05467436
- Testing
- Local anesthetics, IV sedation drugs and analgesics.
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Augusta University
Opioid Use Disorder, Alcohol Use Disorder
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age.
- Conditions
- Opioid Use Disorder, Alcohol Use Disorder, Health Risk Behaviors, Criminal Behavior
- Trial name
- RB (NCT05665179)
- Testing
- Removing Barriers to Recovery
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Michigan
Surgery, Antibiotic
Antibiotic Prescription Relevance Indicators: Calculation From Electronic Health Records
This research focuses on the development and validation of indicators on the relevance of antibiotic prescriptions. The investigators want to propose transferable tools to other healthcare institutions to allow automated…
- Trial name
- ARIPPA (NCT05420168)
- Testing
- Automatic tool to identify inappropriate antibiotic prescriptions
- Where
- 8 sites in France
- Volunteers
- 2,115 people
- Sponsor
- University Hospital, Bordeaux
Substance Use, Substance-Related Disorders
Clinician Practice Companion to Address Youth Substance Use
Substance use, including the use of opioids, cannabis, and other drugs, is common among adolescents and young adults, and overdose has become a leading cause of death among youth in Canada and the United States.
- Conditions
- Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use
- Trial name
- NCT07725289
- Testing
- Practice Companion
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Knee Arthroscopy, Shoulder Arthroscopy
Non-Opioid Prescriptions After Arthroscopic Surgery in Canada (NO PAin)
This is a randomized controlled trial of 200 patients between the ages of 18 and 65 years undergoing outpatient knee or shoulder arthroscopy. Patients will be evaluated clinically at 2 and 6 weeks post-operatively.
- Trial name
- NO PAin (NCT04566250)
- Testing
- Non-Opioid Prescription and Infographic
- Where
- 3 sites in Canada
- Volunteers
- 200 people
- Sponsor
- McMaster University
Inappropriate Drug Prescription and Use
Educational and Informative Interventions to Tackle Inappropriate Use of Drugs in Italy
Pharmacological intervention is an essential step in health promotion. However, lots of drugs are often used in inappropriate ways, especially in elderly patients.
- Trial name
- EDUREDRUG (NCT04030468)
- Testing
- Educational intervention addressed to general practitioners, Informative intervention addressed to patients
- Where
- Italy
- Volunteers
- 4,840 people, healthy volunteers welcome
- Sponsor
- University of Milan
Opioid-Related Disorders, Hepatitis C (HCV)
Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk
This study will test the effectiveness, implementation outcomes, and cost effectiveness of a locally-tailored, health kiosk to reduce overdose, hepatitis C, and HIV risk behavior and improve linkage to care in rural Appalachia.
- Conditions
- Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose
- Trial name
- NCT05657106
- Testing
- Health kiosk
- Where
- United States
- Volunteers
- 752 people, healthy volunteers welcome
- Sponsor
- April M Young
General Practice (GP), Primary Care Settings
Trial to Assess Implementation of New Research in a Primary Care Setting (TRAINS)
In England and Wales, unscheduled care for school-aged children with asthma significantly increases after their return to school in September, a trend linked with decreased asthma preventer prescriptions during the summer…
- Trial name
- (TRAINS) (NCT05226091)
- Testing
- Letter
- Where
- United Kingdom
- Volunteers
- 1,389 people
- Sponsor
- University of Sheffield
Compliance, Patient, Treatment Adherence
Treatment Adherence With Twin-Blocks for Correction of Class II Malocclusion
To compare the effect of two control intervals (once every 4th week or once every 6th week) on the wear time of a Twin Block removable appliance.
- Trial name
- NCT05155774
- Testing
- Twin block
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Region Jönköping County
Medically Unexplained Symptoms
Impact of Humor Prescription on the Emotional Well-being of Patients With Medically Unexplained Symptoms: A Quasi-experimental Study
This study aims to study the effectiveness of the intervention for medically unexplained symptoms(MUS) in terms of changes in emotional well-being before and after the intervention (humor therapy)
- Trial name
- NCT07007013
- Testing
- Humor therapy
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Healthy Participants
Nature Based Therapy With Mindful Walks in Urban Coastal Setting - Barcelona (Spain)
The main objective of the NATURE-MET-B (Barcelona) study is to analyze the effects of a Nature-based Therapy (NbT) on the biopsychological resilience of adults general population through changes in: i) health-related quality of…
- Trial name
- NATURE-MET-B (NCT06622629)
- Testing
- Nature based Therapy (NbT): Planned therapeutic techniques performed in natural settings and based on nature-human active participation and connection, Waiting List
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
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