Clinical trials: Prescription
Programming Languages, Patients
DESIGNING A PROGRAMMING LANGUAGE FOR PATIENT-ORIENTED PRESCRIPTIONS (POP-PL)
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care
- Trial name
- NCT03837418
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Diabetes
MHealth Biometrics for Young People with Diabetes
The investigators aim to undertake a feasibility randomised controlled trial (RCT) to investigate whether mHealth technology, allowing biometric informed feedback and coaching on exercise and PA, can be effective in children with…
- Trial name
- MOTIVATE-HfH (NCT04868851)
- Testing
- Here for Health Only, mHealth technology assisted exercise counselling
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Liverpool John Moores University
Usage of Prescription Opioids
Determining Genetic Biomarkers Predictive of the Development of Prescription Opioid Addiction
This is a clinical study on patients who have been prescribed opioids (narcotic pain relievers) for the treatment of pain, to determine what genetic factors influence outcome of treatment.
- Trial name
- NCT01562353
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Analgesic Solutions
Opiate Dependence, Substance-related Disorders
Prescription Opioid Addiction Treatment Study (POATS)
The purpose of this study is to determine whether treatment outcome for subjects dependent on prescription opioid analgesics can be improved by adding individual drug counseling to the prescription of buprenorphine/naloxone with…
- Conditions
- Opiate Dependence, Substance-related Disorders, Opioid-related Disorders
- Trial name
- NCT00316277
- Testing
- Standard Medical Management (SMM) of Prescription Opiate Abuse, Enhanced Medical Management (EMM) of Prescription Opiate Abuse
- Where
- 12 sites in United States
- Volunteers
- 653 people
- Sponsor
- Mclean Hospital
Depressive Disorder, Major
A Study to Evaluate the Benefit of Opti-Me Application to Different Treatments of MDD
Major depressive disorder (MDD) is a debilitating disease characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite.
- Trial name
- NCT04148612
- Testing
- Opti-Me
- Where
- 2 sites in Israel, Switzerland
- Volunteers
- 390 people
- Sponsor
- ElMindA Ltd
Migraine, Headache
Long-term Atogepant in Real-world Practice
This prospective multicentre observational study aims to evaluate the long-term effectiveness, safety, tolerability, and treatment persistence of atogepant for migraine prevention in routine clinical practice.
- Conditions
- Migraine, Headache, Headache (Migraine), Migraine Disease
- Trial name
- GEMA PROJECT (NCT07699549)
- Testing
- Atogepant 60 mg, Headache diary, Patient-reported outcome measures
- Where
- Spain
- Volunteers
- 513 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Adult Growth Hormone Deficiency
Metabolic Endocrinology and Growth Hormone in Adults
This is a multicentric, longitudinal, observational study with the prospective follow-up of Adult subjects with Growth Hormone Deficiency (AGHD) being treated with Saizen, every six months in the first year and then annually.
- Trial name
- MEGHA FRANCE (NCT01080755)
- Volunteers
- 90 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Opioid Safety, Prescription Opioid Misuse
A Patient-Centered Intervention to Improve Opioid Safety
This is a randomized controlled trial of a multifaceted intervention designed to improve the safety of opioid prescribing. The specific aims of this study are to: (a) evaluate whether a multifaceted intervention (Improving the…
- Conditions
- Opioid Safety, Prescription Opioid Misuse, Chronic Pain
- Trial name
- ISOP (NCT02791399)
- Testing
- ISOP Intervention with the Nurse Care Manager
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- VA Office of Research and Development
Opioid Overdose
Blood Naloxone Levels Following Intradermal Injection in Humans
The main purpose of this study is to evaluate pharmacokinetics/pharmacodynamics of intradermal administration of naloxone in healthy adult subjects.
- Trial name
- NCT05876572
- Testing
- intradermal naloxone, microneedle injection
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bronchiolitis Obliterans, Acute Obliterating Bronchiolitis
Use of Erythromycin in Mustard-Induced Bronchiolitis
We looked for the effectiveness of low-dose long-term prescription of erythromycin in mustard-induced bronchiolitis obliterans
- Trial name
- NCT00367419
- Testing
- Erythromycin
- Where
- Iran
- Sponsor
- Baqiyatallah Medical Sciences University
Cardiac Rehabilitation
A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation
The purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen.
- Trial name
- NCT04555512
- Testing
- Progressive High Intensity Interval Training (PRO-HIIT), Constant High Intensity Interval Training (CON-HIIT)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Substance Use Disorder (SUD), Opioid Use Disorder
Disease Intervention Specialist (DIS) for SUD
This prospective observational study evaluates three Disease Intervention Specialist service models designed to proactively identify and support adults at risk for substance use disorder.
- Conditions
- Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use
- Trial name
- DIS-SUD (NCT07875361)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Ohio State University
Substance Use Disorders, Overdose
Smartphone Intervention for Overdose and COVID-19
This study will examine if the use of a smartphone application called Thrive4Life Connect can help people who use drugs lower their risk of overdose and learn more about COVID-19 vaccines.
- Conditions
- Substance Use Disorders, Overdose, COVID-19
- Trial name
- NCT05518461
- Testing
- iThrive WI Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Overdose
Motivational Interviewing to Increase Uptake of Drug Checking and Safe Drug Use Behaviors to Reduce Overdose
A hybrid type 1 study will be conducted to evaluate efficacy and preliminary implementation considerations for a novel intervention to promote uptake of drug checking services (DCS) and safer drug use behaviors among people who…
- Trial name
- MI-CHANCE (NCT06855836)
- Testing
- MI-CHANCE (TS + FTIR + MI), TS + FTIR + Flu and Hepatitis A Education
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Adverse Drug Effects
The Use of STOPP/START Criteria for Medication Intervention Among Elderly Population Living in a Geriatric Hospital
The purpose of this study is to determine if the use of STOPP/START criteria (STOPP-screening tool of older persons potentially inappropriate prescriptions START-screening tool to alert doctors to right treatment)for medication…
- Trial name
- STOPP (NCT01602744)
- Testing
- STOPP/START screening tools for medication intervention
- Where
- Israel
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Pseudomonas
Impact of Modifications to the Rendering of the Antibiogram on the Prescriptions of Meropenem in Pseudomonas Bacteremia
Modification of the rendering of the antibiogram at the Strasbourg University Hospital in November 2019 with the appearance of the concept of "standard dose" or "high dose" sensitivity.
- Trial name
- Mero-Pyo (NCT06113107)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Hypertension (HTN), Food Insecurity
Navigating Hypertension and Food Insecurity
This multi-site randomized controlled trial uses a community-based approach to evaluate a Food as Medicine program for Native Hawaiian and Pacific Islander (NHPI) adults in Hawaii who have high blood pressure and difficulty…
- Trial name
- NCT07544836
- Testing
- Produce Prescription Only, Community Health Worker navigated Produce Prescription
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Hawaii
Drug Overdose
A Pilot Study of the Bioavailability of Nasal Naloxone
The overall is aim of this pilot study is to give a preliminary estimation of key parameters of the pharmacokinetics of a proper formulation of intranasal naloxone.
- Trial name
- NCT01939444
- Testing
- naloxone intranasal, naloxone intravenous
- Where
- Norway
- Volunteers
- 5 people
- Sponsor
- Norwegian University of Science and Technology
Substance Withdrawal Syndrome
Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal
Prescription opioid addiction is a growing public health problem and more pharmacologic treatments are needed because current approved medications have had limited patient acceptance (naltrexone), limited availability…
- Trial name
- NCT00980044
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Michelle Lofwall
Advanced Cancers
Self Reported Deviations From Opioid Analgesic Prescription
Primary Objective: 1. To determine the frequency of self-reported over and under use of opioid analgesics in patients with advanced cancer.
- Trial name
- NCT00907192
- Testing
- Personal Interview, Questionnaire
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- M.D. Anderson Cancer Center
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