Clinical trials: Pressor Response
Healthy Aging, Cardiovascular Risk Factor
Exercise Pressor Reflex and Lifelong Training
Cardiovascular diseases represent the first mortality cause in the world. Ageing is considered as the most prominent risk factor for this kind of diseases. Also, hypertension represents one of the modifiable risk factors.
- Trial name
- LEaSTCaRe (NCT04013022)
- Testing
- Exercise History
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Blood Pressure, Stress, Physiological
Cardiovascular Reactivity to Physical Stress
It is well-accepted that an exaggerated blood pressure (BP) response to physical stress has a prognostic value, indicating a higher cardiovascular risk (e.g., sudden cardiac death, myocardial infarction, future hypertension, and…
- Trial name
- REACT (NCT06319001)
- Testing
- Low-volume high intensity exercise, Combined intermittent sauna and cold water bath (sauna+cold bath).
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Western Norway University of Applied Sciences
Shock, Septic
Comparison of Vasopressin and Other Pressors in Septic Shock
The purpose of this study is to compare the classical tactics in the treatment of septic shock (dopamine, noradrenalin and dobutamine) to the use of vasopressin as first choice pressor.
- Trial name
- NCT00269685
- Testing
- vasopressin
- Volunteers
- 20 people
- Sponsor
- Université de Sherbrooke
Septic Shock
Hemodynamics Effects of Fludrocortisone on the Pressor Response to Noradrenaline Septic Shock Patients
The benefit of low-dose steroids in septic shock is still debated today, especially with mineralocorticoids. Fludrocortisone is a synthetic mineralocorticoid, an analogue of aldosterone, which has shown, in combination with…
- Trial name
- FLUDROSEPSIS (NCT05001854)
- Testing
- Fludrocortisone
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Rennes University Hospital
Septic Shock
Hemodynamic Effects of Dexmedetomidine in Septic Shock
The current treatment regimen of patients with septic shock requires a sufficient hemodynamic support aiming to preserve tissue oxygen requirements and perfusion.
- Trial name
- NCT02638545
- Testing
- Dexmedetomidine
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- University of Roma La Sapienza
Intubation Complication
Block Pressor Response to Intubation
Laryngoscopy and endotracheal intubation are necessary for effective control of airway and ventilation, but it has deleterious effects such as hypertension and disrhythmia
- Trial name
- NCT05659212
- Testing
- Dexmedetomidine, Magnesium sulphate, Lidocaine
- Volunteers
- 102 people
- Sponsor
- Assiut University
High Blood Pressure
Immediate Pressor Response to Oral Salt
The goal of this study is to establish a diagnostic accuracy of an immediate pressor response to oral salt (IPROS) to identify salt sensitivity of blood pressure (SSBP)
- Trial name
- IPROS (NCT06226636)
- Testing
- salt
- Where
- 2 sites in Zambia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mulungushi University
Pressor Response
Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients
Dexmedetomidine nebulization in sever preeclamptic patients
- Trial name
- NCT07164326
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Septic Shock
Upregulation of Alpha-1 Receptors Upon Septic Shock?
The hallmarks of septic shock are hypovolemia and reduced pressor response to endogenous noradrenaline. The working hypothesis is that the higher the plasma concentration of endogenous noradrenaline will be, the lower the pressor…
- Trial name
- CATACHOC (NCT01856517)
- Testing
- Clonidine
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hypertension, Laparoscopic Cholecystectomy
Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy
Dexmedetomidine provides better hemodynamic stability to the patients with hypertension undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04646317
- Testing
- Dexmedetomidine injection, Normal Saline
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Dr. Ruth K.M. Pfau Civil Hospital, Karachi
Stress, Acute Stress
Neurophysiological and Autonomic Responses to Acute Physical and Emotional Stress: An EEG Study
This study aims to investigate neurophysiological, autonomic, and subjective responses to different acute physical and emotional stress-inducing conditions using a within-subject repeated-measures design.
- Trial name
- NCT07781670
- Testing
- Cold Pressor Test, Negative Autobiographical Memory Recall, Affective Picture-Viewing Task
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Healthy Volunteer
Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response
The purpose of this study is to evaluate the potential effect of ozanimod on pressor response when co-administered with oral tyramine in healthy adult subjects.
- Trial name
- NCT03694119
- Testing
- Phenelzine, Tyramine, ozanimod
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Celgene
Pressor Response, Baroreflex Sensitivity
High Resolution Phenotyping in Healthy Humans
Baroreflex sensitivity is integral to blood pressure regulation, and varies among healthy, normotensive individuals. A reduced compensatory ability of baroreflex buffering in patients with carotid denervation results in blood…
- Conditions
- Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability
- Trial name
- NCT00943774
- Testing
- Physiological maneuvers
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Blood Pressure
Effects of Yoga on Sodium-induced Pressor Responses in African American Adults
This investigation aims to determine the effects of a 4-week yoga intervention on sodium-induced pressor and endothelial function responses as well as markers of renal sodium handling in African American adults.
- Trial name
- NCT05353270
- Testing
- Yoga, Waitlist control
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Texas State University