Clinical trials: Presymptomatic Disease
Asymptomatic Condition
Influence of Muscle Stretching and Neural Mobilizations on Lower Limbs Range of Motion in Asymptomatic Subjects.
First, this study aims to use the straight leg raising test (SLR) and the knee angle extension test (KEA) test associated to a structural differentiation to determine the limitation of the lower limb (muscular or nervous) in…
- Trial name
- NCT05899244
- Testing
- muscle streching exercice, Slider, Tensioner
- Where
- Belgium
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Liege
Asymptomatic Conditions
Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men
Background. The prevalence of obesity has increased in the last two decades. To maintain body weight energy expenditure (EE) should be equal to energy intake (EI).
- Trial name
- RMR (NCT02751840)
- Testing
- Caffeine, Coffee, Decaffeinated
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Aged, Asymptomatic Condition
Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects
Principal aim The main purpose of the study is to describe the distribution of the sagittal profile in elderly subjects in order to bridge the gap present in this type of screening, evaluated in the literature for adults only…
- Trial name
- EOS60 (NCT03237039)
- Testing
- X-ray examination, fall-risk assessment, gait cycle analysis
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Malaria,Falciparum
Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya
This study is a cluster-randomized controlled trial to evaluate the efficacy of community-based mass screening with a malaria rapid diagnostic test, and treatment of participants with positive tests with an appropriate…
- Trial name
- MSaT (NCT02987270)
- Testing
- Dihydroartemisinin-piperaquine
- Volunteers
- 90,000 people, healthy volunteers welcome
- Sponsor
- Simon Kariuki
Asymptomatic Condition
Effect of Osteopathic Technique on Maximum Mouth Opening Width, Masseter Muscle Tone and Stiffness
The purpose of this study is to assess the effect of compression and decompression thecnique on the temporomandibular joint on maximum mouth opening width, masseter muscle tone and stiffness in asymptomatic adults, compared with…
- Trial name
- NCT07670832
- Testing
- Osteopathic Intervention Techniques
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Huntington Disease, White Matter Alterations
Decoding Presymptomatic White Matter Changes in Huntington Disease
WIN-HD is a monocentric longitudinal study comparing premanifest Huntingtin (HTT) mutation carriers and non HTT mutation carriers to determine that white-matter atrophy occurs far earlier than clinical onset in HD using…
- Trial name
- Win-HD (NCT03193099)
- Testing
- Brain imaging, Neurological assessments, Psychological assessments
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Choledocholithiasis, Asymptomatic Condition
The Treatment Effect for Asymptomatic Common Bile Duct Stone
This study is prospective, multicenter study for identify the characteristics of asymptomatic common bile duct stones and effectiveness of treatment.
- Conditions
- Choledocholithiasis, Asymptomatic Condition, Quality of Life
- Trial name
- NCT06215040
- Testing
- Endoscopic retrograde cholangiopancratography
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Asymptomatic Condition
Forces and Translation Distance During an Inferior Glide of the Shoulder
This study evaluates the force and translation distance in the GH joint during a manual inferior glide of the humerus.
- Trial name
- NCT04775628
- Testing
- Inferior glide humerus in GH joint
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Dr. Rob Sillevis,
Asymptomatic Condition
Effects of Different Stretching Techniques on Extensibility, Strength and Range of Motion in Football Athletes
To compare the effects dynamic stretching, passive stretching and self-stretching of the quadriceps muscle on muscle extensibility, hip strength and hip range of motion
- Trial name
- NCT04863976
- Testing
- Dynamic stretching, Passive stretching, Self-stretching
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Colonization, Asymptomatic
A Clinical Simulation Study of a Test Material on the Anterior Nares
The objective of this study is simulate the clinical use of a test material within a 24h window. Efficacy will be simulated as the capacity of the material to reduce or clear the anterior nares bacterial population from…
- Trial name
- NCT05617729
- Testing
- Saline applied via swab, Povidone-iodine based gel
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Center for Innovation and Research Organization
COVID, SARS-CoV 2
COVID-19: Herd Immunity Study in the Czech Republic
The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on…
- Trial name
- SARSCoV2CZPrev (NCT04401085)
- Testing
- SARS-CoV-2 diagnostic rapid test, Quantitative analysis of SARS-CoV-2 antibodies
- Where
- Czechia
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Asymptomatic Condition
Effects of Transcranial Direct Current Stimulation (tDCS) on Rotator Cuff Fatigue.
The aim of this study will be to determine the effects of active tDCS on rotator cuff fatigue. This study will be a randomized, double-blind, sham-controlled, cross-over clinical trial based on non-probabilistic sampling for…
- Trial name
- NCT05210231
- Testing
- Transcranial Direct Current Stimulation
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Pregnancy Complications
Early PrEgnancy Complications Testing
The aim of this study is the early (presymptomatic) detection of pregnancy complications, which could contribute to a preventive treatment.
- Trial name
- ExPECT (NCT04079361)
- Testing
- Blood samples
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Asymptomatic State
Effect of Massage Therapy in Cortisol Level
This study evaluates the effect of a single session of Massage Therapy in salivary cortisol level. All participants were assessed on three conditions: Massage session, rest in supine position listening music, and under normal…
- Trial name
- MTCL (NCT02440412)
- Testing
- Massage Therapy, Rest in supine
- Where
- Chile
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chile
Alzheimer Disease, Mild Cognitive Impairment
Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)
The proposed study is designed to evaluate the performance of the ALTOIDA™ System as a tool to assist physicians in diagnosing Alzheimer's Disease (AD) in real-world clinical settings.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Memory Disorders, Cognitive Impairment
- Trial name
- AltoidaML (NCT02843529)
- Testing
- Altoida: neuropsychological, MRI, EEG and CSF biomarkers
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Altoida
Asymptomatic Condition
The Immediate Effects of Spinal Manipulative Therapy on Kinetic and Kinematic Symmetry.
Athletes have been exposed to an ever increasing training load and subsequent biomechanical overload due to a constant demand for performance enhancement.
- Trial name
- NCT03361592
- Testing
- Spinal Manipulative Therapy
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Asymptomatic Condition
Effects of Mulligan Bent Leg Raise With and Without Bowen Therapy on Hamstring Tightness in Asymptomatic Adults
Hamstring tightness is a common problem caused by a sedentary lifestyle and can have negative effects on posture and musculoskeletal function.
- Trial name
- NCT06197945
- Testing
- Mulligan bent leg raise, Mulligan bent leg raise with Bowen therapy
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Asymptomatic Diseases
The Effects of Valsalva Maneuver on Head, Neck and Upper Extremity Arterial Systems
The aim of this study is to determine the relation between arterial diameter and flow of carotis interna, brachial artery and radial artery before and after valsalva maneuver.
- Trial name
- NCT02832310
- Testing
- valsalva maneuver
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Faecal Incontinence, Asymptomatic Condition
Anal Canal Functional Assessment Using EndoFLIP
Faecal incontinence (FI) is characterized by involuntary loss of rectal content through the anal canal. FI is psychologically and socially debilitating problem that can dramatically affect patient's quality of life, often in…
- Trial name
- NCT04741893
- Testing
- EndoFLIP
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Asymptomatic Conditions
Assessing the Effect of Lettuce on Intestinal Water Content Through Magnetic Resonance Imaging of the Small Bowel
When patients have bowel surgery they are sometimes left with a stoma, where the small bowel exits onto the wall of the abdomen, not into the colon.
- Trial name
- LETIS (NCT02939716)
- Testing
- Rhubarb, Bread, Lettuce
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham