Clinical trials: Preterm Birth
Mother-Infant Interaction, Premature Birth
The Effect Of Baby Smell On The Amount Of Breast Milk, Salivary Cortisol Level And Mother Baby Attachment
The goal of this [type of study: randomized controlled clinical trial] is to [determine the effect of applying the scent of premature newborns who cannot be breastfed to the mother on the mother's milk amount, salivary cortisol…
- Trial name
- NCT06096961
- Testing
- Baby smell
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Premature Infant, Clustered Care
Development and Effectiveness Evaluation of a Clustered Care Guideline Within Individualized Developmental Care: RCT
The Individualized Developmental Care (IDC) model was developed to minimize the negative impact of the neonatal intensive care environment and to support infants' physiological stability.
- Conditions
- Premature Infant, Clustered Care, Neonatal Intensive Care Unit, Developmental Care
- Trial name
- Guideline (NCT07052786)
- Testing
- Infants will receive group care based on individualized developmental care according to the guide., Standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Wheezing
A Phase 3 Trial of the Effect of Motavizumab Prophylaxis on Reduction of Serious Early Childhood Wheezing in Infants
The primary objective of this study is to assess the efficacy of motavizumab compared to placebo when administered monthly to preterm infants during their first RSV season for the reduction of the incidence of serious early…
- Trial name
- NCT00628303
- Testing
- Motavizumab
- Volunteers
- healthy volunteers welcome
- Sponsor
- MedImmune LLC
Low Birth Weight, Prematurity
The Impact of Extreme Environmental and Security Conditions on Prematurity and Low Birth Weight Rates
Numerous reports indicate that various extreme environmental and security-related situations during pregnancy may increase the risk of prematurity, LBW, and miscarriage, as these events increase both the incidence and intensity…
- Trial name
- NCT07531134
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Obstetric Labour, Premature
This Study Will Investigate the Effect of Single Oral Doses of Retosiban on Cardiac Repolarization, With Moxifloxacin as a Positive Control in Healthy Volunteers.
This will be a randomized, placebo-controlled, single, oral dose, four-way Williams crossover study design in healthy male and female subjects.
- Trial name
- NCT01702376
- Testing
- Retosiban 100 mg, Retosiban 800 mg, Moxifloxacin 400 mg
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fetal Membranes, Premature Rupture
Myometrial Thickness as a Predictor for the Latency Interval in PPROM
100 women divided into 3 groups: Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks.
- Trial name
- NCT02380560
- Testing
- Ultrasonographic examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Respiratory Syncytial Virus Infections
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)
The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and…
- Trial name
- MELODY (NCT03979313)
- Testing
- MEDI8897
- Where
- 198 sites in United States, Argentina and 29 more
- Volunteers
- 3,012 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Other Preterm Infants
Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.
While using the device as a cushion, the passive distribution of pressure over bony skull prominences of infants will protect against formation of pressure ulcers.
- Trial name
- INV-CS-001 (NCT02224859)
- Testing
- HCP will place the Invictus Cranial Support Device (CSD) on the patient, human intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Invictus Medical, Inc.
Preterm Labor, Periodontitis
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery
Investigators have shown the presence of elevated proinflammatory cytokines in amniotic fluid in patients in preterm labor.However, there is limited and mostly negative evidence that the elevation of these mediators in gingival…
- Trial name
- NCT02521688
- Testing
- incisional biopsy from placenta and GCF sample
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Preterm Birth, Artificial Intelligence (AI) in Diagnosis
Does AI Make Clinicians More Appropriately Confident? A Randomized Study in Preterm Birth Prediction
The goal of this randomized questionnaire-based study is to evaluate how different presentations of artificial intelligence (AI) decision support influence clinical judgment among medical doctors working in obstetrics and…
- Trial name
- NCT07402668
- Testing
- AI prediction (binary), AI risk estimate (%)
- Where
- 18 sites in Denmark
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Premature Birth, Preeclampsia
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
This study evaluates the effectiveness of maternal supplementation with Docosahexaenoic acid (DHA) early in pregnancy to reduce the incidence of deep placentation disorders: preterm birth, preterm labor, preterm premature rupture…
- Conditions
- Premature Birth, Preeclampsia, Fetal Growth Retardation, Stillbirth
- Trial name
- NCT02336243
- Testing
- Docosahexaenoic acid (DHA)
- Where
- 5 sites in Chile
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Milk Collection, Breast Pumping
Breast Massage and Hot Compress Application to Mothers With Premature Babies at Newborn Intensive Care University Effect on Milk Release and Anxiety
This research was carried out in order to determine the effect of breast massage and hot compresses on milk release and anxiety to mothers with premature babies in YYBU (Neonatal Intensive Care Unit)
- Conditions
- Breast Milk Collection, Breast Pumping, Massage Therapy
- Trial name
- NCT05420389
- Testing
- breast massage, hot compress, breast massage-hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seyma Ertugral
Preterm Labor
UTEROCERVİCAL ANGLE MEASUREMENT IN SPONTANEOUS PRETERM BIRTH (UAMSPB)
İn this study Study; Between August 2018 and August 2019, the Ministry of Health, Medeniyet University, Göztepe Training and Research Hospital, Gynecology and Obstetrics Clinic Will be Included for Routine Control Purposes…
- Trial name
- UAMSPB (NCT03623685)
- Testing
- measurement of uterocervical angle
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Pregnancy Complications, Obstetric Labor, Premature
Interest of Measuring Lung Elasticity ELASTOgraphy in the Fetus in the Case of PreMAture Childbirth Threat
The objective of the study was to evaluated the feasibility and reproducibility of the measurement of lung elasticity report / fetal liver according to gestational age in a group of patients with a normal course of pregnancy and…
- Trial name
- ELASTOMAP (NCT02870608)
- Testing
- lung and liver elastography measurement of fetus
- Where
- France
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Face, Newborn
Fitting of Commonly Available Face Masks for Late Preterm and Term Infants
Around ten percent of newborn infants require positive pressure ventilation (PPV) in the delivery room. This is most commonly delivered using a round or anatomically shaped face mask attached to a T-piece device, self-inflating…
- Conditions
- Face, Newborn, Preterm Infant
- Trial name
- CAFF (NCT03369028)
- Testing
- 2D and 3D image of infants´ faces
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Premature Birth of Newborn
Enteral Feeding and Early Gut Colonization of Preterm Infants
The aim of this study is to evaluate the potential role of the enteral feeding systems on the bacterial colonization of premature infants during their NICU admittance and its evolution after 2 years, which is the age when the…
- Trial name
- PRECOL (NCT02502916)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Thermometry
Comparison of Three Methods of Taking Temperatures in the Newborn Intensive Care Unit
Preterm infants will have their body temperature measured by three different devices in order to evaluate whether the newest device, a temporal artery scanning thermometer, is accurate for patients in the preterm period.
- Trial name
- NCT01012128
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Gestational Hypertension, Prematurity
Effects of Exercise During Pregnancy on Maternal and Child Health: a Randomized Clinical Trial
The Pamela Study is a clinical trial carried out during pregnancy to assess the potential effects of physical activity during pregnancy among previously inactive women.
- Conditions
- Gestational Hypertension, Prematurity, Maternal Post-partum Depression, Maternal Post-partum Weight Retention
- Trial name
- PAMELA (NCT02148965)
- Testing
- Physical Exercise / Physical Activity
- Where
- Brazil
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
The Primary Outcome is Preterm Delivery Before 28 Weeks Gestational Age Compared to Women With One vs Two Cerclages Placed
Single Versus Double Suture Cervical Cerclage to Prevent Preterm Birth
Cerclage placement is known to be beneficial in prevention of preterm birth when placed inn a certain subset of patients. Clinically, the number of sutures can also vary by surgeon preference to one or two sutures in one…
- Trial name
- NCT04742647
- Testing
- Double cerclage, Single cerclage
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
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