Clinical trials: Preterm Birth Complication
Fetal Membranes, Premature Rupture
Myometrial Thickness as a Predictor for the Latency Interval in PPROM
100 women divided into 3 groups: Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks.
- Trial name
- NCT02380560
- Testing
- Ultrasonographic examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Preterm Labor, Periodontitis
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery
Investigators have shown the presence of elevated proinflammatory cytokines in amniotic fluid in patients in preterm labor.However, there is limited and mostly negative evidence that the elevation of these mediators in gingival…
- Trial name
- NCT02521688
- Testing
- incisional biopsy from placenta and GCF sample
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Preterm Birth, Artificial Intelligence (AI) in Diagnosis
Does AI Make Clinicians More Appropriately Confident? A Randomized Study in Preterm Birth Prediction
The goal of this randomized questionnaire-based study is to evaluate how different presentations of artificial intelligence (AI) decision support influence clinical judgment among medical doctors working in obstetrics and…
- Trial name
- NCT07402668
- Testing
- AI prediction (binary), AI risk estimate (%)
- Where
- 18 sites in Denmark
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Premature Birth, Preeclampsia
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
This study evaluates the effectiveness of maternal supplementation with Docosahexaenoic acid (DHA) early in pregnancy to reduce the incidence of deep placentation disorders: preterm birth, preterm labor, preterm premature rupture…
- Conditions
- Premature Birth, Preeclampsia, Fetal Growth Retardation, Stillbirth
- Trial name
- NCT02336243
- Testing
- Docosahexaenoic acid (DHA)
- Where
- 5 sites in Chile
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Milk Collection, Breast Pumping
Breast Massage and Hot Compress Application to Mothers With Premature Babies at Newborn Intensive Care University Effect on Milk Release and Anxiety
This research was carried out in order to determine the effect of breast massage and hot compresses on milk release and anxiety to mothers with premature babies in YYBU (Neonatal Intensive Care Unit)
- Conditions
- Breast Milk Collection, Breast Pumping, Massage Therapy
- Trial name
- NCT05420389
- Testing
- breast massage, hot compress, breast massage-hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seyma Ertugral
Preterm Labor
UTEROCERVİCAL ANGLE MEASUREMENT IN SPONTANEOUS PRETERM BIRTH (UAMSPB)
İn this study Study; Between August 2018 and August 2019, the Ministry of Health, Medeniyet University, Göztepe Training and Research Hospital, Gynecology and Obstetrics Clinic Will be Included for Routine Control Purposes…
- Trial name
- UAMSPB (NCT03623685)
- Testing
- measurement of uterocervical angle
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Pregnancy Complications, Obstetric Labor, Premature
Interest of Measuring Lung Elasticity ELASTOgraphy in the Fetus in the Case of PreMAture Childbirth Threat
The objective of the study was to evaluated the feasibility and reproducibility of the measurement of lung elasticity report / fetal liver according to gestational age in a group of patients with a normal course of pregnancy and…
- Trial name
- ELASTOMAP (NCT02870608)
- Testing
- lung and liver elastography measurement of fetus
- Where
- France
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Face, Newborn
Fitting of Commonly Available Face Masks for Late Preterm and Term Infants
Around ten percent of newborn infants require positive pressure ventilation (PPV) in the delivery room. This is most commonly delivered using a round or anatomically shaped face mask attached to a T-piece device, self-inflating…
- Conditions
- Face, Newborn, Preterm Infant
- Trial name
- CAFF (NCT03369028)
- Testing
- 2D and 3D image of infants´ faces
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Premature Birth of Newborn
Enteral Feeding and Early Gut Colonization of Preterm Infants
The aim of this study is to evaluate the potential role of the enteral feeding systems on the bacterial colonization of premature infants during their NICU admittance and its evolution after 2 years, which is the age when the…
- Trial name
- PRECOL (NCT02502916)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gestational Hypertension, Prematurity
Effects of Exercise During Pregnancy on Maternal and Child Health: a Randomized Clinical Trial
The Pamela Study is a clinical trial carried out during pregnancy to assess the potential effects of physical activity during pregnancy among previously inactive women.
- Conditions
- Gestational Hypertension, Prematurity, Maternal Post-partum Depression, Maternal Post-partum Weight Retention
- Trial name
- PAMELA (NCT02148965)
- Testing
- Physical Exercise / Physical Activity
- Where
- Brazil
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Obstetric Labor, Premature
Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone
The aim of this study is to investigate the In Vitro and In Vivo effect of progesterone on immature myeloid cells (IMC), inflammation characteristics and maturation into dendritic cells (DC).
- Trial name
- NCT03211338
- Testing
- Culture with progesterone, Culture without progesterone, Culture with growth factors
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Newborn; Vitality, Nursing Caries
Effect of Intranasal Breast Milk Administration in Preterm Infants
The aim of the study was to investigate the effect of intranasal breast milk administration on cerebral oxygenation level, vital signs and time to full oral feeding in preterm infants.
- Conditions
- Newborn; Vitality, Nursing Caries, Breast Feeding
- Trial name
- NCT06706115
- Testing
- Intranasal human breast milk
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Preterm Birth, Small for Gestational Age (SGA)
Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries
This study, Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries (ABLE), is designed as a 2-arm randomized controlled trial (RCT) focused on pregnant individuals and newborn infants.
- Conditions
- Preterm Birth, Small for Gestational Age (SGA), Stillbirth, Bacteriuria (Asymptomatic) in Pregnancy
- Trial name
- ABLE (NCT06723392)
- Testing
- Oral nitrofurantoin monohydrate/macrocrystals
- Where
- 7 sites in Bangladesh, Democratic Republic of the Congo and 4 more
- Volunteers
- 1,134 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Sensation Disorders
Relationship Between Sensory Processing and Motor Development
The aim of this study is to analyse correlation between the sensory processing and motor development in preterm infants.
- Trial name
- NCT02889887
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Premature Newborn, Nurse
The Effect of Massage, Wipe Bathing and Tub Bathing on Physiological Measurements of Late Premature Newborns
Purpose: This randomized experimental study aimed to analyze the effect of massage, wipe bathing and tub bathing of late premature newborns on their physiological measurements. Design and Methods: .
- Conditions
- Premature Newborn, Nurse, Physiological Measurements
- Trial name
- NCT04602130
- Testing
- Control, Massage, Sponge Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Inonu University
Apnea of Newborn, Preterm Labor
Analyze Changes in Respiratory Rate When Using the Scare Respirator
Pilot study of 10 preterm, who are going to be randomly placed to 3 phases : 2 hour of basal observation of respiratory rate, heart rate, saturation, NIPS and aEEG recording, 2 hours with a 20cycles/minute with "scare…
- Trial name
- RESPSUS (NCT04584814)
- Testing
- without any device, scare ventilator at 20, scare ventilator at 40
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pre-Term, Neonatal Infection
Non-invasive Measurement of Neonatal Central and Peripheral Hemodynamics
Non-invasively neonatal cardiac output can be measured by multiple methods, but the gold standard still remains conventional echocardiography. It is accurate, but needs a long training for new users to assess cardiac function.
- Trial name
- NInHeDyNeo (NCT04200807)
- Testing
- Ultrasound Cardiac Output Monitor (USCOM 1A)
- Where
- Lithuania
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Preterm Labor, Premature Birth
Effectiveness of ACS in Extreme Preemies
This is a randomized prospective clinical study that will evaluate the effects of antenatal corticosteroid administration (ACS) vs.
- Trial name
- NCT02351310
- Testing
- Betamethasone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Preterm Birth
Effect of Immersion Bathing and Showering Applications on Comfort Level and Physiological Parameters of Newborn
Effect of immersion bathing and showering applications on comfort level and physiological parameters of Newborn
- Trial name
- NCT04811742
- Testing
- bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Okan University