Clinical trials: Preterm Contractions, active
Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation
A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter
The purpose of this study is to assess the safety and feasibility of the investigational catheter for mapping the atrial and ventricular regions of the heart.
- Conditions
- Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- FEATHER (NCT07116525)
- Testing
- Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 90 people
- Sponsor
- Biosense Webster, Inc.
Premature Ventricular Complexes, Premature Ventricular Contraction (PVC)
Catheter Ablation Versus Anti-arrhythmic Drugs for Premature Ventricular Complexes
Premature ventricular complexes (PVCs) are extra, abnormal heart beats arising from the ventricles of the heart and are the most common ventricular arrhythmia.
- Conditions
- Premature Ventricular Complexes, Premature Ventricular Contraction (PVC), Premature Ventricular Beats
- Trial name
- CAAD-PVC (NCT07445334)
- Testing
- Catheter ablation, Medical therapy: Anti-arrhythmic drugs (AAD) and/or beta-adrenergic blocking agents (BB)
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Western Sydney Local Health District
Ventricular Arrhythmia, Ventricular Tachycardia
IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry
This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular…
- Conditions
- Ventricular Arrhythmia, Ventricular Tachycardia, Premature Ventricular Contraction (PVC), Cardiomyopathy
- Trial name
- IVTCC (NCT04520347)
- Where
- 41 sites in United States, Canada and 5 more
- Volunteers
- 10,000 people
- Sponsor
- University of California, Los Angeles
Focal Ventricular Arrhythmias, Premature Ventricular Contractions
Treatment of Focal Ventricular Tachycardias Using a Pulsed Field Ablation From a Point Ablation Catheter Short Title FOCUS-PFA
The purpose of this study is to examine the use of a point ablation catheter (Farapoint, Boston Scientific) in the mapping and ablation of focal ventricular arrhythmias (premature ventricular contractions or ventricular…
- Conditions
- Focal Ventricular Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardias
- Trial name
- FOCUS PFA (NCT06747013)
- Testing
- Point Ablation Catheter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vivek Reddy
Andersen Tawil Syndrome, Multifocal Ectopic Purkinje-related Premature Contractions
N-of-1 in ATS and MEPPC
Rationale: Andersen-Tawil syndrome (ATS) is a very rare heritable cardiac arrhythmia syndrome that is characterized by the triad of periodic paralysis, physical dysmorphisms, and ventricular arrhythmias, including bidirectional…
- Trial name
- NCT06205550
- Testing
- Flecainide, Flecainide + beta-blocker
- Volunteers
- 10 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ablation of Arrhythmias, Premature Ventricular Contractions
Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation
This study is investigating whether using ultrasound directly inside the heart during ablation of heart rhythm disorders in the ventricles can reduce radiation exposure for patients.
- Conditions
- Ablation of Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardia, Ventricular Arrhythmia
- Trial name
- REAL-ICE (NCT07201506)
- Testing
- PVC and VT ablation with ICE, PVC and VT ablation without ICE
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Premature Ventricular Contraction (PVC)
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine.
- Trial name
- NCT03218137
- Testing
- Adenosine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Atrial Fibrillation, Ventricular Tachycardia
Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathies
The goal of this observational study is to determine if electrophysiologic mapping and cardiac MRI can help identify patients that have genetic forms of cardiomyopathy that are at high risk for development of dangerous…
- Conditions
- Atrial Fibrillation, Ventricular Tachycardia, Premature Ventricular Contraction
- Trial name
- NCT06575881
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Vanderbilt University Medical Center
Premature Ventricular Contractions
Concealed Myocardial Abnormalities by Cardiac Magnetic Resonance Imaging in Idiopathic VT
Idiopathic Ventricular arrhythmia (VAs) refers to VAs that occur in the absence of clinically apparent structural heart disease.
- Trial name
- NCT06146556
- Testing
- catheter based ablation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myocarditis, Premature Ventricular Contractions
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry
To assess potential link between unrecognized myocardial inflammation (myocarditis) and premature ventricular contractions (PVCs) associated with and without reduced Left ventricular ejection fraction (LVEF) through comprehensive…
- Conditions
- Myocarditis, Premature Ventricular Contractions, Ventricular Tachycardia (VT)
- Trial name
- MAVERIC (NCT05158751)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC)
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or…
- Conditions
- Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
- Trial name
- DISCRETE AF (NCT07220525)
- Testing
- HGNS Use Randomized Instructions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC)
Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular…
- Conditions
- Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation
- Trial name
- AI-VT (NCT06964152)
- Testing
- Computational electrocardiography and cardiac computed tomography mapping
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Premature Ventricular Contractions
Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles
This randomized, prospective, parallel, single-blind, multicenter clinical trial investigates the efficacy and safety of intracardiac echocardiography (ICE)-guided catheter ablation versus pressure-sensing catheter ablation alone…
- Trial name
- NCT06898281
- Testing
- intracardiac echocardiography (ICE)-guided catheter ablation, Pressure-sensing catheter ablation alone
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shanghai Chest Hospital
Premature Ventricular Contractions, Ventricular Tachycardia
CHU Dual-Energy Ablation in Ventricular Arrhythmia
The objective of this study is to evaluate the safety of the dual-energy ablation catheter manufactured by Shanghai MicroPort EP Medical Technology Co., Ltd. in the treatment of tachyarrhythmias.
- Trial name
- CHU-VA (NCT07503769)
- Testing
- ablation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai MicroPort EP MedTech Co., Ltd.
Premature Ventricular Beats, Premature Ventricular Complexes
Flecainide in Idiopathic Premature Ventricular Contractions and Related Cardiomyopathy
The UNIFLECA study is a prospective, single-arm, observational cohort evaluating the efficacy, safety, and tolerability of flecainide (in the form of Sanocard) in adults with frequent idiopathic premature ventricular contractions…
- Conditions
- Premature Ventricular Beats, Premature Ventricular Complexes, Premature Ventricular Contraction (PVC), Arrhythmia Ventricular
- Trial name
- UNIFLECA (NCT06949748)
- Testing
- Flecainide (monotherapy)
- Where
- 6 sites in Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Athens
PVC - Premature Ventricular Contraction, Myocarditis
Role of Novel ILR in the Management of PVCs
This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months.
- Trial name
- NCT06060548
- Testing
- Monitoring of patients presenting with PVCs
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Premature Ventricular Contractions, Ventricular Dysfunction, Left
Prophylactic Frequent Premature Ventricular complexeS sUPPression on Left ventriculaR Function impairmEnt in aSymptomatic patientS
The main objective of the study is to demonstrate that prophylactic treatment of patients with asymptomatic frequent (>10%) PVCs is superior to simple follow-up strategy with no therapy to prevent subsequent LV dysfunction at 24…
- Trial name
- SUPPRESS (NCT05784051)
- Testing
- Experimental group, Control group
- Volunteers
- 298 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ELGAN (22-28SA), Extremely Low Gestational Age Newborns
Cardiovascular Immaturity in Extremely Low Gestational Age Newborns: a Fundamental Prospective Study
Birth is a major turning point in the life of the newborn, as it moves from intrauterine life to extrauterine life. This sudden transition forces the newborn to adapt quickly.
- Conditions
- ELGAN (22-28SA), Extremely Low Gestational Age Newborns, Cardiovascular Immaturity
- Trial name
- ELGAN AMINES (NCT06737965)
- Testing
- Medical abortion, Foetopathology exam, Outcomes mesurement
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Montpellier
Tachycardia, Paroxysmal Supraventricular Tachycardia
AI-Based Differential Diagnosis and Localization of Tachycardia Using ECG: Multicenter Registry (EP-AI ASSIST)
This multicenter retrospective study aims to develop, validate, and clinically apply an artificial intelligence (AI)-powered electrocardiography (ECG) algorithm for the diagnosis and prognostic prediction of cardiovascular…
- Conditions
- Tachycardia, Paroxysmal Supraventricular Tachycardia, Wolff-Parkinson-White Syndrome, Premature Ventricular Contractions
- Trial name
- EP-AI ASSIST (NCT07859020)
- Testing
- AI-based ECG Diagnostic and Localization Algorithm
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Inha University Hospital
Arrhythmia
Comprehensive Biomarker ProfiliNg in PatieNts With VEntriCular TachyCardia, PremAtuRe VEntricular Contractions, and AVNRT
To systematically evaluate multiple biomarkers in patients ventricular tachycardia (VT), premature ventricular contractions (PVC), atrioventricular nodal reentrant tachycardia (AVNRT) undergoing catheter ablation to elucidate…
- Trial name
- CONNECT-CARE (NCT07389928)
- Volunteers
- 200 people
- Sponsor
- University of Luebeck