Clinical trials: Preterm Milk
Premature Birth, Breastmilk Collection
Targeted Nutrition for Moderate to Late Preterm Infants
This study will be comparing the postnatal growth of moderate to late preterm infants in the Neonatal Intensive Care Unit (NICU) born between gestational ages of 30 weeks 0 days to 35 weeks and 6 days who are receiving enteral…
- Conditions
- Premature Birth, Breastmilk Collection, Postnatal Growth Restriction
- Trial name
- NCT05515614
- Testing
- Targeted Fortification, Enfamil Liquid Human Milk Fortifier
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Premature
Effect of Docosahexaenoic Acid (DHA)-Enriched Human Milk in Premature Newborns
Several recent publications showed a reduction in the level of DHA and/or an increase in the arachidonic acid (AA)/DHA ratio in the milk of mother.
- Trial name
- DHARMA (NCT01062373)
- Testing
- Supplementation of lactating mothers who has delivered prematurely with DHA
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pertussis
Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
Young infants are most vulnerable to severe disease and even death when infected with Bordetella Pertussis. The current vaccines and vaccination programs do not guarantee protection of neonates.
- Trial name
- MAMA (NCT02511327)
- Testing
- Infant pertussis vaccination
- Where
- Belgium
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Infant Sleep Problems, Circadian Rhythm
Chrononutrition in Preterm Infants: a Randomised Controlled Trial of Time-matched Breast Milk Feeding and Its Effects on Sleep and Circadian Development
This study investigates whether the timing of feeding expressed breast milk influences infant sleep and circadian (day-night) development in preterm infants.
- Conditions
- Infant Sleep Problems, Circadian Rhythm, Neurodevelopment
- Trial name
- NCT07533578
- Testing
- Chronobiologically Timed Feeding of Expressed Breast Milk, Usual Feeding Practice (Untimed Expressed Breast Milk)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Milk Production
A Trial Comparing Two Breast Pumps in Mothers Expressing Milk for Their Preterm Infants
This is a randomised controlled trial investigating the performance of two, 'state of the art' electric breast pumps in mothers who have delivered preterm infants.
- Trial name
- NCT00887991
- Where
- United Kingdom
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health
Breastfeeding, Postnatal Depression
Mother and Late Preterm Lactation Study
Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and…
- Conditions
- Breastfeeding, Postnatal Depression, Stress, Psychological, Preterm Infant
- Trial name
- MAPLeS (NCT03791749)
- Testing
- Breastfeeding Support
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College, London
Infant, Very Low Birth Weight
Human Milk Fortifier and Cytokine Profile
This is a research study investigating if adding human milk fortifier to a preterm babies breast milk feedings affects the baby's immune system.
- Trial name
- NCT00601081
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Low-Birth-Weight Infant, Premature Infants
Analyzer of Human Milk: Applicability in Clinical Practice in Order to Achieve the Best Nutrition for Infants
An observational and prospective study involving about 30 healthy lactating mothers whose preterm infant(s) is/are hospitalized at Neonatal Intensive Care Unit after childbirth and who can provide enough maternal milk (3mL) to be…
- Trial name
- MISTU (NCT02971904)
- Testing
- human milk collection
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Early Life Nutrition Brazil
Breast Milk
Influence of Medical Clown Activity on Milk Production of Mothers of Premature Infants
The aim of this study is to determine whether medical clown activity enables relaxation of mothers of premature infants, and as a result increases their breast milk production.
- Trial name
- NCT01758133
- Testing
- Exposure to medical clown activities
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Milk Expression, Breast
Efficacy of Breast Milk in Healing of Skin Damage
The population of the research will be preterm infants born 35-36 weeks of gestation, hospitalized in the Neonatal Intensive Care Unit of Karaman State Hospital, whose skin is damaged due to Intravenous (IV) vascular access…
- Trial name
- NCT05390372
- Testing
- human milk, Routine care group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Very Preterm Infant, Very Low Birthweight
LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk
The goal of the LIFT-UP randomized controlled trial is to evaluate the efficacy of feeding routinely and fortified human milk using a standardized clinical protocol to very low birthweight (VLBW) or very preterm (VPT) infants in…
- Trial name
- LIFT-UP RCT (NCT06765863)
- Testing
- Human Milk Fortifier, Volume targets
- Where
- 4 sites in India
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Breast Milk Expression, Premature Birth of Newborn
How Effect Olive Oil and Eoprotin on Immunological Parameters and Growth
This study aims to compare immunologic parameters of 60 patients who are 1-28 days-aged, below 1500-gram body weight, born before 32 weeks of gestational age and fed with eoprotin or olive-oil fortified breast milk.
- Trial name
- RDS (NCT02832011)
- Testing
- olive oil, Eoprotin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- nihat demir
Virtual Reality, Breast Milk Expression
Breast Milk Expression With Virtual Reality
The study is a randomized controlled study planned to determine the effect of the VRBaby-Pump application applied to mothers who gave birth preterm, on the mother's breast milk expression experience, transition process, and milk…
- Trial name
- NCT06164223
- Testing
- VR Baby Pump
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Pain, Acute, Preterm Infant
Olfactive Stimulation Interventions With Mothers' Milk on Preterm Pain Response
Repeated and untreated pain can lead to long-term consequences in preterm infants, such as pain hypersensitivity and impaired motor and intellectual development.
- Conditions
- Pain, Acute, Preterm Infant, Breast Milk
- Trial name
- NCT04062513
- Testing
- Olfactive stimulation intervention with familiarization, Olfactive stimulation intervention, Standard care
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Breast Milk Expression
Early Initiation of Milk Expression in Mothers of Very Low Birth Weight Infants
Compelling evidence exists that breast milk helps protect very premature infants from prematurity-specific morbidities. Unfortunately, mothers of premature infants often exhibit delayed lactogenesis stage II (when the milk "comes…
- Trial name
- NCT01892085
- Testing
- Early initiation, Intermediate expression, Late initiation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Florida
Breast Milk Collection, Breast Pumping
Breast Massage and Hot Compress Application to Mothers With Premature Babies at Newborn Intensive Care University Effect on Milk Release and Anxiety
This research was carried out in order to determine the effect of breast massage and hot compresses on milk release and anxiety to mothers with premature babies in YYBU (Neonatal Intensive Care Unit)
- Conditions
- Breast Milk Collection, Breast Pumping, Massage Therapy
- Trial name
- NCT05420389
- Testing
- breast massage, hot compress, breast massage-hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seyma Ertugral
Preterm Birth, Pain, Acute
Reducing Pain During Heel Blood Collection in Preterm Newborns
Pharmacological and non-pharmacological methods are used to control interventional pain in preterm newborns. Non-pharmacological methods should be preferred in the management of pain, especially during painful minor invasive…
- Trial name
- NCT05431452
- Testing
- Pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Preterm Birth, Inadequate Milk Production
Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants
This study aims to evaluate the feasibility and effects of nicotinamide riboside (NR) supplementation in lactating mothers of infants expected to be hospitalized in the neonatal intensive care unit (NICU) for at least four weeks.
- Trial name
- MOONRISE (NCT04614714)
- Testing
- Nicotinamide Riboside (NR)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Lactation
Dietary Lutein and the Retinopathy of Prematurity
The clinical trial aspect of this study is the provision of a lutein supplement to lactating women and compare the amount of lutein in the milk and blood with lactating women who do not receive the lutein supplement.
- Trial name
- NCT00672230
- Testing
- Lutein supplement
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Necrotizing Enterocolitis
Pilot Study of the Feasibility of Feeding Preterm Infants With Fresh Versus Frozen Mother's Own Breast Milk in the NICU
Necrotizing enterocolitis (NEC) is a severe inflammatory disorder of the intestine that primarily affects very low birth weight (<1,500 g)/very preterm infants (≤32 weeks' gestation); it is also the leading cause of death in the…
- Trial name
- NCT03258957
- Testing
- Fresh Milk
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiqing Sun