Clinical trials: Prevention
Pregnancy Related, Diet Modification
Motivational Interviewing for Getting Healthy TodaY Study
The present study aims to test and rigorously evaluate the effectiveness of a computer-assisted motivational interviewing (CAMI) intervention that has already been shown to be successful with young women by reducing the risk of…
- Trial name
- MIGHTY (NCT03410225)
- Testing
- CAMI-TPP, CAMI-Fitness
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cervical Cancer, Cervical Dysplasia
Self-sampling for Non-attenders to Cervical Cancer Screening
The trial will evaluate whether self-sampling and human papillomavirus (HPV) testing may increase cervical cancer screening attendance among under-screened women in Czech Republic.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- KOPRETINA (NCT04226313)
- Testing
- Self-sampling by Evalyn Brush, Self sampling by Evalyn Brush home or in GP´s clinic
- Where
- Czechia
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Malaria
School Based Malaria Control in Ugandan Schoolchildren
The investigators hypothesize that schoolchildren treated with IPT using DP over one year of follow-up will have a different risk of clinical malaria compared to those treated with placebo.
- Trial name
- SBMC (NCT01231880)
- Testing
- Four monthly IPT with dihydroartemisinin Piperaquine (DP), Monthly IPT using DP
- Where
- Uganda
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Makerere University
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Assessing the Impact of a Plant-Based Diet for Diabetes Prevention
The primary purpose of this study is to determine the sex-specific metabolic and molecular response, among adults with prediabetes, when moving from a Western Diet to plant-based diet.
- Trial name
- NCT06571279
- Testing
- Plant-based diet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Jean L. Fry
Cervical Cancer Prevention
Study on the Safety, Humoral Immune Response, and Memory B Cell Response Characteristics of Sequential 9-Valent HPV Vaccination
This is a single-center, prospective, open-label, partially randomized, matched-controlled trial designed as a cohort study. The study plans to enroll 360 healthy female participants aged 18 to 45 years, divided into three…
- Trial name
- NCT07530679
- Testing
- 9-valent HPV vaccination at months 0 and 6, 9-valent HPV vaccination at months 0 , 1 and 6
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
HIV Infections
A Behavioral Intervention to Reduce Sexual Risk Among African-American Men Who Have Sex With Men
The purpose of this project is to test the efficacy of an HIV prevention behavioral intervention to reduce sexual risk among African-American men who have sex with men (MSM).
- Trial name
- NCT00691496
- Testing
- Behavioral intervention to reduce sexual risk among African-American men who have sex with men
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Teenage Pregnancy
Girl2Girl: Harnessing Text Messaging to Reduce Teenage Pregnancy Among LGB Girls
The purpose of this study is to finalize and rigorously evaluate Girl2Girl, a novel text messaging-based teenage pregnancy prevention (TPP) program designed specifically for LGB women ages 14-18 years, nation-wide.
- Trial name
- Girl2Girl (NCT03029962)
- Testing
- Girl2Girl
- Where
- United States
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Sars-CoV2, COVID19
A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
A multicenter randomized clinical trial aiming to assess the efficacy of hydroxychloroquine associated to Zinc compared to hydroxychloroquine, in the prevention of Military Health Professionals Exposed to SARS CoV2 in Tunisia
- Trial name
- COVID-Milit (NCT04377646)
- Testing
- Hydroxychloroquine, Zinc
- Where
- Tunisia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Military Hospital of Tunis
Injury;Sports
Post-exercise Recovery of DOMS in Recreational Athletes
The main goal of this study was to investigate the effectiveness of cryo-sauna in preventing the development of DOMS in the lower extremity.
- Trial name
- NCT05757518
- Testing
- Cryosauna
- Where
- Poland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sports Injury
Epidemiology of Roller Hockey Related Injuries.
Roller Hockey is a sport played on a 40*20 metres rink characterized by combined periods of high intensity and short breaks, there´s a lack of epidemiological studies in this field.
- Trial name
- NCT05006820
- Where
- Spain
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Ebola Hemorrhagic Fever
Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus
The purpose of this study is to characterize the safety and pharmacology of single administrations of AVI-6002, a post-exposure prophylaxis candidate treatment for Ebolavirus.
- Trial name
- NCT01353027
- Testing
- AVI-6002
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sarepta Therapeutics, Inc.
Post Exposure Prophylaxis, Occupational Exposure HIV Infections Hepatitis B Hepatitis C Post-Exposure Prophylaxis
Impact of Health Education on Knowledge, Attitude and Practice of Post-exposure Prophylaxis
The goal of this study is to learn whether a short education programme helps healthcare workers know more about post-exposure prophylaxis (PEP).
- Trial name
- NCT07330427
- Testing
- Health Education
- Where
- Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aswan University
HIV
SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension
The overall purpose of this SEARCH CAB-LA (Cabotegravir Injectable Suspension) randomized extension study is to determine if adding the option of CAB-LA as a prevention choice using a person-centered dynamic choice HIV (human…
- Trial name
- NCT05549726
- Testing
- Cabotegravir Injectable Suspension, Dynamic Choice Delivery Model, Standard of Care
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ventilator-Associated Pneumonia Prevention and Intensive Care Nursing Care
Theory-Based Educational Program for VAP Prevention and Nursing Care in Intensive Care Units
Ventilator-associated pneumonia (VAP) is an important challenge in intensive care and requires nurses to apply evidence-based preventive practices consistently in mechanically ventilated patients.
- Trial name
- TSEP-VAP-2026 (NCT07820826)
- Testing
- Theory-Based Structured Educational Program, Usual Care
- Where
- Jordan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- JAWAD AHMAD ABU-SHENNAR
Postural Stability, Dynamic Knee Valgus
The Effect Subtalar Joint Pronation on Postural Stability and Lower Extremity Alignment
The lower extremity consists of sequent columns. The deviation of one segment from its normal alignment in the lower extremity also affects the alignment of the other segments.
- Conditions
- Postural Stability, Dynamic Knee Valgus, Injury Prevention
- Trial name
- NCT05606835
- Testing
- Postural stability assessment, Frontal plan prjection angle, Foot and Ankle Ability Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Substance Abuse
Preventing Drug Abuse Among Sexual Minority Youth
The planned randomized clinical trial will longitudinally test a tailored, web-based drug abuse prevention program with a nationwide sample of 15- to 17-year-old sexual minority youth (youth who identify as gay, lesbian…
- Trial name
- NCT03954535
- Testing
- Free2b
- Where
- United States
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Septic Acute Kidney Injury
KDIGO Bundle to Prevent AKI in Sepsis
Summary: Controlled, prospective, randomized and randomized clinical trial of two intervention groups (standard care vs. preventive recommendations the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines for AKI) of…
- Trial name
- NCT04222361
- Testing
- Preventive recommendations for kidney disease: guidelines for improving overall outcomes (KDIGO) for AKI
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital General Universitario Elche
Thromboembolic Stroke, Aspirin
The Prevention of Thromboembolic Complications Associated With Coil Embolization
Clopidogrel has been to be reported to be superior to aspirin for the prevention of thromboembolic complications associated with coil embolization in patients with ruptured aneurysms.
- Conditions
- Thromboembolic Stroke, Aspirin, Clopidogrel, Coil Embolization
- Trial name
- NCT05512546
- Testing
- Aspir-Low Pill
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Muhammad Hassan
Developmental Delay
Bright by Three (BB3) Effectiveness Study
The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting…
- Trial name
- NCT02717390
- Testing
- Bright By Three (BB3), Texts for Child Safety (TCS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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