Clinical trials: Prevention Intervention
Sexual Violence
Pilot Study of the Ntombi Vimbela Sexual Violence Intervention Among Female Tertiary Students in South Africa
The pilot study aims to test the acceptability of content, feasibility of delivery methods and preliminary assessment of outcomes from the implementation of the Ntombi Vimbela intervention with volunteer groups of female first…
- Trial name
- NCT04607564
- Testing
- Ntombi Vimbela! intervention
- Where
- 6 sites in South Africa
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Medical Research Council, South Africa
Cognitive Decline
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Singapore's rising dementia incidence with an ageing population presents an urgent need for effective interventions that delay or prevent cognitive decline.
- Trial name
- ADL+ 2 (NCT07141160)
- Testing
- Combined: Mobile app + 6WELLS, Remote mobile based app
- Where
- Singapore
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Delivery Modality of BETTER Intervention
The Virtual BETTER Study
The focus of this project is to examine how delivering virtual care impacts health behaviour change for patients with chronic illnesses compared to in-person visits using a chronic disease prevention and screening (CDPS) program…
- Trial name
- NCT05425797
- Testing
- In-Person Prevention Practitioner Visit, Video-Call Prevention Practitioner Visit, Phone Prevention Practitioner Visit
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Aggression
Healthy Brains & Behavior: Understanding and Treating Youth Aggression
Understanding the joint neurobiological and social bases to aggression is critical to future attempts to tackle this major public health problem.
- Trial name
- HBB (NCT00842439)
- Testing
- CBI, NUT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
High Blood Pressure, Hypertension
Using Nonpharmacological Approaches in Hypertension Prevention and Management
The goal of this randomized controlled trial is to test the effectiveness of a four-module nutrition education resource promoting nonpharmacological approaches to prevent and manage hypertension.
- Trial name
- NCT06490575
- Testing
- Educational Intervention Based on Protection Motivation Theory to Improve Knowledge and Promote Nonpharmacological Approaches to Prevent and Manage Hypertension among Adults
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Mental Disorder
VIA Family 4 Year Follow-up of a Family-based Preventive Intervention
This study aims to investigate the long-term effects (2.5 years after post-intervention) of a preventive family-based intervention (VIA Family) compared with treatment as usual (TAU) for children of parents with a severe mental…
- Trial name
- NCT06218693
- Testing
- VIA Family, Treatment As Usual (TAU)
- Where
- Denmark
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Behavior Change Interventions
Monocular-Camera-Based Mobile Exergame for Type 2 Diabetes Prevention
Exergames have demonstrated potential as effective interventions for promoting physical activity and preventing type 2 diabetes (T2D), particularly among older adults.
- Trial name
- NCT06950528
- Testing
- Control group, Kinect group, Monocular group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Use Cessation, Addiction
An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use.
- Trial name
- NCT06483412
- Testing
- Healthy Futures: Alternative-to-Suspension Curriculum
- Where
- United States
- Volunteers
- 2,540 people, healthy volunteers welcome
- Sponsor
- Stanford University
HIV Infections, Sexually Transmitted Diseases
Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM
The purpose of this program evaluation is to determine whether the "Many Men, Many Voices" HIV/STD prevention intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing among African-American men who…
- Trial name
- 3MV (NCT00137631)
- Testing
- Many Men, Many Voices (3MV)
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Perimenopausal Depression, Depressive Symptoms
Testing the Efficacy of Mindfulness-based Stress Reduction in the Prevention of Perimenopausal Depression
Depression is the leading cause of disability worldwide and a risk factor for other diseases. While women are at elevated risk for depression in general, the menopause transition is a particularly vulnerable time for many women…
- Trial name
- NCT03526523
- Testing
- Mindfulness-based stress reduction
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Regina
Substance Use Disorders, Health Promotion
Preventing Problem Behavior Among Middle School Students
Problem behaviors such as drug use, violence, and school misconduct increase during adolescence. This study evaluated a program designed to prevent problem behaviors in middle school students; the program includes classroom…
- Trial name
- NCT00062959
- Testing
- Going Places: School program to prevent problem behavior
- Volunteers
- 2,768 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Women's Health, Annual Visit
Precision Nudging Drives Wellness Visit Attendance at Scale
The purpose of the present randomized controlled trial is to explore the effectiveness of a 12-month well woman digital health intervention leveraging Precision Nudging - the application of behavioral science and reinforcement…
- Conditions
- Women's Health, Annual Visit, Well Visit, Health Behavior
- Trial name
- NCT05509049
- Testing
- Precision nudging, Standard of care
- Where
- United States
- Volunteers
- 30,068 people, healthy volunteers welcome
- Sponsor
- Lirio
Cancer
Selenium in the Prevention of Cancer
This is a pilot study proceeding an intended international trial. Hypothesis: Daily intake of selenium supplementation in the form of selenium-enriched yeast tablets will reduce the risk of cancer in healthy individuals.
- Trial name
- DK PRECISE (NCT01819649)
- Testing
- SelenoPRECISE selenium-enriched yeast tablet, Pharma Nord Denmark A/S
- Where
- Denmark
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Alcohol Abuse
Alcohol Early Intervention for Freshmen
Alcohol abuse among college students is a significant and long-standing public health issue. The transition into college is marked by substantial increases in alcohol abuse and problems, suggesting the importance of interventions…
- Trial name
- Transitions (NCT00852033)
- Testing
- Brief Motivational Intervention (BMI), Parent Based Intervention plus booster, Combined brief motivational intervention and parent based intervention plus boosters for both interventions
- Where
- United States
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Mother to Child Transmission, Pregnancy in Adolescence
Digital Intervention to Address Stigma Among Pregnant Adolescents Living With HIV
Pregnant adolescents living with HIV (ALHIV) in Kenya frequently experience stigma and difficulty telling a family member about their HIV and pregnancy status.
- Conditions
- Mother to Child Transmission, Pregnancy in Adolescence, Social Stigma, Self Disclosure
- Trial name
- NCT05383755
- Testing
- Digital intervention for pregnant adolescents living with HIV
- Where
- Kenya
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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