Clinical trials: Prevention Program, open to volunteers
Ageing
Effectiveness of the WHO ICOPE (Integrated Care for Older People) Program in Preventing Age-related Functional Decline (ICOPE Trial.Fr)
The World Health Organization (WHO) has designed an integrated care program (ICOPE) aimed at maintaining the functions of elderly people to preserve their autonomy.
- Trial name
- ICOPE Fr (NCT06676839)
- Testing
- the complete ICOPE program
- Where
- 6 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Toulouse
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Rheumatic Heart Disease in Children
School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions
The overall objective of the PREVENT trial is to evaluate the effectiveness of an integrated, school-based program for the prevention of rheumatic heart disease (RHD) in regions with an endemic pattern of RHD.
- Trial name
- PREVENT (NCT06720272)
- Testing
- School nurse program
- Where
- 2 sites in Nepal, Zambia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Thomas Pilgrim
Substance Use, Harm Reduction
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
The primary goal of this study is to test the effectiveness of the iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment) curriculum, a novel drug education and diversion program, in approximately 300…
- Conditions
- Substance Use, Harm Reduction, Adolescent Behavior
- Trial name
- NCT06115746
- Testing
- iDECIDE
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Hospital-based Violence Intervention, Community Firearm Violence
The HVIP+ Community Model
The present study will use an optimization randomized control trial design to test the preliminary efficacy of a Hospital-based Violence Intervention Program (HVIP) in Central Arkansas.
- Conditions
- Hospital-based Violence Intervention, Community Firearm Violence, Firearm Behaviors
- Trial name
- NCT07539142
- Testing
- Brief Bedside, Peer Support, Case Management + Voucher
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Arkansas
Cancer
SUNRISE Aims to Create a Comprehensive, Engaging, and Sustainable Digital Health Promotion Program That Not Only Addresses Immediate Health Behaviours But Also Instils Lifelong Healthy Habits Among Adolescents. It is a Unique, Digitally Enhanced Program Combining Different Digital Solutions With New
SUNRISE aims to create a comprehensive, engaging, and sustainable digital health promotion program that not only addresses immediate health behaviours but also instills lifelong healthy habits among adolescents.
- Trial name
- SUNRISE_2 (NCT06931847)
- Testing
- SUNRISE program
- Where
- 8 sites in Belgium, Cyprus and 6 more
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Biobizkaia Health Research Institute
Substance Use, Self Esteem
Native Spirit: Significant Aim 3: Intervention
The proposed research will used community-based participatory research methods in an urban-based American Indian (AI) community to adapt, implement, and evaluate an after-school program, called Native Spirit (NS), that seeks to…
- Conditions
- Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
- Trial name
- NCT06785311
- Testing
- Native Spirit After-School Program
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Colorectal Cancer Screening, Colorectal Cancer Prevention
Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may…
- Conditions
- Colorectal Cancer Screening, Colorectal Cancer Prevention, Colorectal Cancer
- Trial name
- LIFE-SCREEN (NCT06827366)
- Testing
- Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Leon Berard
Aggression Childhood, Teen Dating Violence
Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services
The goal of this clinical trial is to learn if this intervention (Social Skills, Problem Solving, emotion Regulation, and psycho-Education on Trauma: A Trauma-Informed Peer Aggression and Teen Dating Violence Prevention Program…
- Trial name
- SPARE (NCT06769282)
- Testing
- Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Rhode Island Hospital
Suicide Prevention
HAVEN-Connect Youth Suicide Prevention
HAVEN=CONNECT is a comprehensive depression and suicide prevention intervention that is designed to be integrated into predominantly Black churches, a strategically ideal location for mental health intervention for Black youth.
- Trial name
- HAVEN (NCT07401940)
- Testing
- HAVEN-Connect, HAVEN Suicide Prevention
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- George Washington University
Skin Cancer, Skin Cancer Prevention
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
Skin cancer is a significant public health concern, even in an Asian society like Singapore where it ranks among the top 10 cancers.
- Conditions
- Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
- Trial name
- NCT07247123
- Testing
- Skin Cancer Self-Detection Educational Program with gain-framing, Skin Cancer Self-Detection Educational Program with loss-framing, Wait-list Control
- Where
- Singapore
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Traumatic Brain Injury, Spinal Cord Injuries
Continuous Passive Motion Versus Heterotopic Ossification
The investigators hypothesize that Heterotopic Ossification (HO) formation can be suppressed if the application of a Continuous Passive Motion (CPM) device can be performed for a substantial amount of time.
- Conditions
- Traumatic Brain Injury, Spinal Cord Injuries, Stroke
- Trial name
- CPMversusHO (NCT05906056)
- Testing
- Continuous Passive Motion (CPM), Conventional physiotherapy (PT), Zoledronic Acid Injection
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- University of Ioannina
Mental Health, Well-being
A Mentalization Based Prevention Program to Foster Well-Being and Mental Health in Pre-Adolescent Children and Their Families
The FLOW project involves the implementation and rigorous evaluation of an evidence-based, multi-level mentalization prevention program targeting social and psychological determinants of well-being in four European countries…
- Trial name
- FLOW (NCT07494929)
- Testing
- Lighthouse Program, Mentalization Based Skills Training, Lighthouse program parenting guidebook
- Where
- 4 sites in Germany, Lithuania and 2 more
- Volunteers
- 15,200 people, healthy volunteers welcome
- Sponsor
- Svenja Taubner
Substance-Related Disorders, Adverse Childhood Experiences
Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program
Primary Objective: Conduct a rigorous evaluation of a prevention-based intervention designed to mitigate the harms of adverse childhood experiences (ACEs) exposure and prevent future ACEs, substance use, and overdose within 36…
- Trial name
- NCT06236100
- Testing
- Strengthening Families Program + Family Advocate, Strengthening Families Program
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- RTI International
Hypertension
Team Lifestyle Immersion Hypertension Control Project
This project is focuses on reducing the risk and progression of hypertension among a population that records high incidence of hypertension and other chronic ailments such as heart disease, diabetes, kidney failure, and obesity…
- Trial name
- TLIP (NCT07201948)
- Testing
- Lifestyle Immersion Intervention that will address Nutrition, Physical Fitness, and BP Self-Monitoring3 Elements:
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Alzheimer Disease
GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype
The purpose of the Alzheimer's Prevention Registry GeneMatch program is to identify a large group of people interested in participating in research studies or clinical trials based in part on their genetic background.
- Trial name
- NCT02564692
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Banner Health
PreDiabetes
Small Steps for Big Changes - Healthy Cities Implementation Science
Small Steps for Big Changes (SSBC) is a diet and exercise counselling program that significantly reduces the risk of developing Type 2 Diabetes (T2D).
- Trial name
- HCIS (NCT06440395)
- Testing
- Behavioural: Small Steps for Big Changes Diabetes Prevention Program
- Where
- 12 sites in Canada
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Carcinoma
Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers
This clinical trial studies whether home-based respiratory muscle training (RMT) and aerobic exercise (AE) programs can be used to improve lung health in current and former cigarette smokers.
- Trial name
- NCT07553819
- Testing
- Accelerometry, Aerobic Exercise, Biospecimen Collection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Deglutition Disorders in Infants, Chronic Tube Feeding in Hospitalized Infants
Parent Implemented Oral Nutrition, Eating, and Esophageal Reflexes Reintegration Protocol: RCT
Feeding dysfunction remains a major unmet challenge among neonatal ICU survivors, frequently leading to prolonged tube feeding or gastrostomy at discharge, increased healthcare utilization, substantial socioeconomic burden, and…
- Trial name
- PIONEER (NCT07035912)
- Testing
- PIONEER Protocol
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital