Clinical trials: Prevention of Colorectal Cancer
Colorectal Cancer Control and Prevention
Life Expectancy-informed Colorectal Cancer Screening
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life expectancy notification to clinicians delivered via the electronic…
- Trial name
- CRC (NCT07141901)
- Testing
- Decision Tool
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Kathryn Martinez
Breast Cancer Screening, Cervical Cancer Screening
Cancer Awareness Among Syrian Migrants
This study aims to develop and evaluate a theory-based educational intervention to improve cancer screening participation among Syrian migrants in Turkey.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colorectal Cancer Screening, Cancer Prevention Behavior
- Trial name
- NCT07541105
- Testing
- PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program
- Volunteers
- 30 people
- Sponsor
- Toros University
Colorectal Cancer Prevention
The Beans to Enrich the Gut Microbiome vs. Obesity's Negative Effects (BE GONE) Trial
You are being asked to take part in this study because either you are a survivor who has a previous history of colorectal cancer or an MD Anderson patient who had a precancerous colorectal polyp or you have a previous history of…
- Trial name
- NCT02843425
- Testing
- Regular Diet, Navy Beans (Canned)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer, Prevention
A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans
African Americans face racial disparities in colorectal cancer (CRC), with lower screening rates and higher incidence and mortality rates.
- Trial name
- NCT05903885
- Testing
- On-site Fecal Immunochemical Test (FIT) Kit Distribution, On-site With Social Media Advertising Fecal Immunochemical Test (FIT) Kit Distribution
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Colorectal Cancer Control and Prevention
Self-Reported Colorectal Cancer Screening Uptake
This randomized controlled trial evaluated the effect of a Health Belief Model-based multicomponent education program on colorectal cancer screening completion, knowledge, health beliefs, and screening attitudes among adults aged…
- Trial name
- CRC-HBM (NCT07778875)
- Testing
- Health Belief Model-Based Colorectal Cancer Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Polyps Colorectal, Colonoscopy
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI.
- Conditions
- Polyps Colorectal, Colonoscopy, Optical Biopsy, Colorectal Cancer Control and Prevention
- Trial name
- FAIR (NCT07158203)
- Testing
- CADx simultaneously, CADx delayed
- Where
- 2 sites in Norway, Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Colorectal Neoplasms, Colorectal Cancer Prevention
ULTRA-high-risk Surveillance to Avoid Future Events: the ULTRA-SAFE Trial
The ULTRA-SAFE clinical trial is a prospective, randomized study designed to address the limitations of current "one-size-fits-all" colorectal cancer surveillance guidelines.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer Prevention, Surveillance Colonoscopy
- Trial name
- ULTRA-SAFE (NCT07378930)
- Testing
- Early triage using Fecal immunochemical test
- Where
- 4 sites in Taiwan
- Volunteers
- 940 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer Control and Prevention, Colorectal Cancer Screening
Use of a Colorectal Cancer Screening Decision Support Tool in Primary Care
The research question we pose is, Does a colorectal cancer (CRC) screening decision support tool offered in advance of primary care visits increase CRC screening completion rates? Our work aims to answer this question by…
- Conditions
- Colorectal Cancer Control and Prevention, Colorectal Cancer Screening, Shared Decision Making, Decision Aid
- Trial name
- NCT06625983
- Testing
- CRC decision tool
- Where
- United States
- Volunteers
- 9,205 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cascade Testing, Lynch Syndrome
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services.
- Conditions
- Cascade Testing, Lynch Syndrome, Decision Making, Colorectal Cancer
- Trial name
- NCT07106359
- Testing
- Information Letter and Booklet, Information Letter
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Colorectal Cancer Prevention, Colorectal Adenoma
BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention
This research study is a prospective, single-arm clinical trial to assess the effect of a dietary intervention for more plant-based and less animal-based food intake on secondary bile acid production, gut microbiota, circulating…
- Trial name
- BILMOD (NCT07162337)
- Testing
- Increased Plant-Based Diet and Decreased Animal-Based Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer Control and Prevention
Prediction Model of Colorectal Adenoma Recurrence-Carcinogenesis Risk With TCM-WM Multimodal Feature Fusion
This project focuses on developing a risk prediction model for the recurrence and malignant transformation of colorectal adenomas by integrating multimodal features from both Traditional Chinese Medicine (TCM) and Western…
- Trial name
- NCT07611266
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Cancer Screening, Colorectal Cancer Prevention
Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may…
- Conditions
- Colorectal Cancer Screening, Colorectal Cancer Prevention, Colorectal Cancer
- Trial name
- LIFE-SCREEN (NCT06827366)
- Testing
- Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Leon Berard
Colorectal Cancer Prevention
Colorectal Cancer Prevention Research Study: Eat Right, Screen Right
The Eat Right, Screen Right Extension program aims to help adult learners manage nutrition risks and screening options for colorectal cancer prevention.
- Trial name
- NCT07393906
- Testing
- Web-based module
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Cancer Prevention, Colorectal Adenoma
Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
This research study is an open-label Phase 1 Exploratory/Pilot clinical trial to measure the effects of the incretin mimetic, tirzepatide, on tissue, urine, blood, and microbiome biomarkers associated with colorectal cancer risk…
- Trial name
- PROSPECT (NCT07095517)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer Prevention, Colorectal Cancer (Diagnosis)
Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).
Low-residue diet (LRD) in patient improves the quality of the colon cleanliness and thus the adenoma detection rate (ADR). This is a key criterion in colonoscopy screening for colorectal cancer (CRC).
- Conditions
- Colorectal Cancer Prevention, Colorectal Cancer (Diagnosis), Colorectal Adenocarcinoma
- Trial name
- POG (NCT07361575)
- Testing
- Colonoscopy, Questionnaires, Pre-colonoscopy diet according to the investigator's oral instructions
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Clinique Paris-Bercy
Colon Cancer Prevention, Polyp Colorectal
Delayed Surveillance Colonoscopy Following Piecemeal EMR
This multicenter, prospective, randomized non inferiority trial, conducted at four Israeli hospitals, will evaluate whether a relaxed surveillance strategy after piecemeal endoscopic mucosal resection (pEMR) of large non…
- Trial name
- NCT07328308
- Testing
- Colonoscopy after bowel cleansing
- Where
- Israel
- Volunteers
- 760 people
- Sponsor
- Rambam Health Care Campus
Health Behavior, Colorectal Neoplasms
Health Behavior Change in High-Risk Colorectal Cancer Individuals
Background Colorectal cancer is a significant health concern. For individuals identified as being at high risk for developing this disease, adopting healthy lifestyle behaviors is a powerful way to lower that risk.
- Conditions
- Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods
- Trial name
- NCT07262840
- Testing
- Multi-component Health Promotion Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Colorectal Cancer Prevention
Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps
The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large…
- Trial name
- Px7 (NCT06335420)
- Testing
- Carrot juice from Yellowstone carrots cultivars
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Odense University Hospital
Breast Cancer Prevention, Colorectal Cancer Prevention
PR-CEAL: Community Outreach Engagement Group
The United States Preventive Services Task Force (USPSTF) recommends regular screenings for breast, cervical, and colorectal cancer.
- Conditions
- Breast Cancer Prevention, Colorectal Cancer Prevention, Cervical Cancer Prevention
- Trial name
- PR-CEAL:COEG (NCT07214051)
- Testing
- Cancer Screening Information
- Where
- Puerto Rico
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico Comprehensive Cancer Center
Colorectal Cancer Control and Prevention
Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial
The goal of this clinical trial is to assess whether messages generated by a large language model (LLM), including both static and conversational formats, can increase colorectal cancer (CRC) screening intentions among U.S.
- Trial name
- NCT07107152
- Testing
- single GPT generated message, AI Chatbot, Expert-Written Patient Materials
- Where
- United States
- Volunteers
- 915 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania