Clinical trials: Prevention of Suicidal Behavior
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Children and Adolescents with Suicidal Thoughts And/or Behaviour
Evidence shows that there are very few evidence-based tools or interventions specifically targeting suicidality in children and adolescents.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviors
- Trial name
- Co-crea K&J (NCT06776328)
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Suicidal Ideation, Suicidal Behavior
Intravenous Ketamine for Acute Suicidal Crisis and Psychiatric Hospital Length of Stay
This randomized, double-blind, active placebo-controlled superiority trial will evaluate whether intravenous esketamine reduces time to psychiatric hospital discharge in adults hospitalized because of acute suicide risk.
- Trial name
- NCT07888933
- Testing
- Esketamine, Midazolam (Intravenous)
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Suicide Risk
MIN PLAN VS CBT for Suicide Prevention
1. To investigate the effectiveness of Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP) in University students with Suicide Risk 2.
- Trial name
- NCT05095233
- Testing
- Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP), Min Plan Tool
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Syeda AYAT E ZAINAB Ali
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Suicidal Behaviour Disorder
Prevention of Suicidal Behavior Through the VIGILANS Protocol: the Restoration of Social Connection Hypothesis
The World Health Organization (WHO) estimates, with 800,000 annual deaths, that suicide is the second leading cause of death in people aged 10 to 44 and thus recognizes suicide prevention as a public health priority.
- Trial name
- RECONEX (NCT05227183)
- Testing
- The virtual version of the Social stress task : V-TSST
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Suicide and Self-harm
Suicide Prevention for Criminal Legal Involved Managed Care Subscribers
The goal of this clinical trial is to test the effects of a suicide prevention intervention for individuals released from jail. The main question it aims to answer is: Does the use of Caring Contacts improve subscriber engagement…
- Trial name
- NCT05579600
- Testing
- Caring Contacts letters
- Where
- United States
- Volunteers
- 45,155 people
- Sponsor
- Butler Hospital
Suicide, Suicide Prevention
Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial
Pragmatic randomized controlled trial to compare the effectiveness of two-way Caring Contacts text messages vs. one-way Caring Contacts text messages vs. enhanced usual care for suicide prevention in adults and adolescents.
- Conditions
- Suicide, Suicide Prevention, Suicide and Self-harm
- Trial name
- SPRING (NCT06128239)
- Testing
- Caring Contacts
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Female, Borderline Personality Disorder
DIalectical Behavior Therapy and Acceptance Commitment Therapy Short Program for BOrderLine persOnality Disorder
According to the World Health Organization 1 death by suicide occurs every 40 seconds, leading suicide prevention to one of the public health priority.
- Trial name
- DIABOLO (NCT03880071)
- Testing
- DBT+ACT, DBT
- Where
- France
- Sponsor
- University Hospital, Montpellier
Suicide, Suicidal Ideation
ReliefLink: A Preventative Mobile Toolkit for Follow-Up Care of Psychiatric Patients
The purpose of this study is to increase use and availability, as well as assess the feasibility of the ReliefLink (RL) application for use in conjunction with standard care to promote psychological health and prevent suicidal…
- Trial name
- NCT02691221
- Testing
- Relief Link Application Daily Tasks
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Emory University
Suicide Prevention, Informal Caregivers
Needs Assessment Among Carers of Someone With Suicidal Thoughts
With this study the investigators would like to gain insight into the experienced needs carers of individuals with suicidal thoughts, who attempted suicide or who died by suicide.
- Trial name
- NCT06611956
- Testing
- No intervention (observational study)
- Where
- Belgium
- Volunteers
- 2,255 people
- Sponsor
- University Ghent
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Psychiatric Hospitalization
Implementation of Caring Contacts
This quality improvement (QI) project will adapt and improve an evidence-based suicide-prevention initiative for Sunnybrook patients at high risk of suicide following psychiatric inpatient discharge, targeting one of Sunnybrook's…
- Trial name
- NCT05294549
- Testing
- Caring Contact
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Sunnybrook Health Sciences Centre
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Depression, Major Depressive Disorder
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional…
- Conditions
- Depression, Major Depressive Disorder, Suicidal Ideation
- Trial name
- NCT05977439
- Testing
- Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Suicide Prevention
Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap . Hospitalization offers a crucial opportunity for life-preserving intervention .
- Trial name
- HOPAIR (NCT07119671)
- Testing
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hôpital le Vinatier
Suicidal Ideation, Suicide Attempts
A Feasibility Study of a Suicide Prevention Video
This initial study is a pilot feasibility study with a primary objective of assessing the feasibility of a larger study by evaluating the procedures and methodology, as well as collecting pilot data.
- Conditions
- Suicidal Ideation, Suicide Attempts, Psychiatric Illness
- Trial name
- NCT05119946
- Testing
- Suicide prevention video, Standard suicide treatment
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Fraser Health