Clinical trials: Preventive Intervention
Cancer and Chronic Disease Prevention
BETTER HEALTH: Durham
The BETTER intervention consists of supportive meetings between a specially trained prevention practitioner nurse and individuals aged 40-64 years to review recommended chronic disease prevention and screening activities (CDPS).
- Trial name
- NCT03052959
- Testing
- Immediate Intervention, Wait List Intervention
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Tobacco Cessation, Media Use
Adolescent Smoking Cessation in Pediatric Primary Care
This is a study of the effectiveness of adolescent smoking cessation interventions in pediatric primary care settings. Our specific aims are to: 1.
- Trial name
- Smokebusters (NCT01312480)
- Testing
- 5A's Model, Media Use Assessment
- Where
- United States
- Volunteers
- 10,967 people, healthy volunteers welcome
- Sponsor
- American Academy of Pediatrics
Physical Performance, Fear of Falling
Falls Prevention Evaluation and Development for Older Adults in the Community
Exercise-based fall prevention programmes with strength and balance components have been shown to reduce the rate of falls, risk of falling, fractures and injuries.
- Trial name
- FREDA (NCT04788251)
- Testing
- Exercise-based fall prevention intervention (Modified Otago Exercise Programme and Modified Stepping On Programme), Wait-list control
- Where
- 2 sites in Singapore
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Geriatric Education and Research Institute
Cerebrovascular Disease
Individualized Antithrombotic Therapy for Patients With Ischemic Cerebrovascular Disease
To investigate the therapeutic effect of individualized treatment of antiplatelet in secondary prevention of ischemic stroke.
- Trial name
- NCT03471169
- Testing
- Desirable TEG, Undesirable TEG
- Where
- China
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Healthy
A 4-week Study of Mifepristone in the Prevention of Risperidone-induced Weight Gain in Healthy Male Volunteers
This is a 28-day, single-center, double-blind, placebo-controlled inpatient study of the administration of risperidone alone or in combination with mifepristone in healthy adult male volunteers to determine the average change in…
- Trial name
- NCT00698022
- Testing
- Risperidone, Mifepristone
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Sleep-Disordered Breathing
HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men
Randomized clinical trial evaluating the effect of acetazolamide on sleep disordered breathing in women compared to men travelling to 3600 m.
- Trial name
- NCT06498531
- Testing
- Acetazolamide
- Where
- Kyrgyzstan
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Opioid Overdose
UnityPhilly Response App for Overdose Reversal
The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app.
- Trial name
- NCT06466005
- Testing
- UnityPhilly app
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Drexel University
HIV, Pre-exposure Prophylaxis
Life Steps for PrEP for Youth
This is a formative study, designed to provide information required to tailor Life-Steps for Pre-Exposure Prophylaxis (PrEP), an evidence-based cognitive behavioral adherence intervention, to enhance PrEP uptake and adherence in…
- Conditions
- HIV, Pre-exposure Prophylaxis, Medication Adherence
- Trial name
- LSPY (NCT03805451)
- Testing
- Life Steps for PrEP for Youth
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Breast Cancer
Vitamin D and Mammographic Breast Density
There is some evidence that vitamin D could be used to reduce breast cancer risk. Randomized controlled trials would provide definitive evidence about this effect.
- Trial name
- EVIDENSE (NCT01747720)
- Testing
- Vitamin D3
- Where
- Canada
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Education, Nursing
The Effect of Mobile Augmented Reality Application on Nursing Students' Knowledge Skills and Motivation
The aim of this study was to examine the effects of a mobile augmented reality application on nursing students' knowledge, skills, and motivation regarding pressure injuries.
- Trial name
- NCT06675760
- Testing
- The intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Adherence to Medication Regime
Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin
In the last few years, early treatment of HIV-infected individuals, or "treatment as prevention (TasP), and pre-exposure prophylaxis with antiretroviral drugs among HIV-negative people at very high-risk of acquiring the infection…
- Trial name
- TasP/PrEP (NCT02237027)
- Testing
- TasP using ART regimen as per Benin guidelines, PrEP using Truvada
- Where
- Benin
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Injury of Hip and Thigh
Analysis of Different Hip Adductors Exercises
Groin injuries present a major problem in sports due to its high frequency, long-lasting symptoms and high risk of re-injury. The most common groin injury is the adductor strain (around two thirds of all groin injuries), while…
- Trial name
- NCT04101786
- Testing
- Hip adductors exercise variations
- Where
- Slovenia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Suicide Prevention, User Experience
User Evaluation of Zelfmoord1813.be and Its Related Websites
Monitoring the availability and accessibility of suicide prevention information in Flanders remains crucial. In 2022, 1,024 people died by suicide in Flanders, and approximately 10,000 individuals required emergency care…
- Trial name
- NCT07071922
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cocaine Abuse, Cocaine-Related Disorders
Medications for Stopping Cocaine Dependence and Preventing Relapse
Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found.
- Trial name
- NCT00218023
- Testing
- Modafinil, Levodopa/Carbidopa, Naltrexone HCl
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anaesthesia, Toxicity
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
The purpose of this prospective randomised study is to investigate electrocardiographic alterations after intravascular injection of three different test solutions of bupivacaine and epinephrine in anaesthetised children up to 16…
- Trial name
- NCT01091766
- Testing
- intravenous injection of test solution
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Role, Nurses
Clarification of Nurses' Expected Role in Health Promotion
The purpose of this study is to implement and evaluate ROLE-AP, a multi-component program to clarify primary care nurses' expected role in health promotion.
- Trial name
- ROLE-AP (NCT04726696)
- Testing
- ROLE-AP programme
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Radius Fractures
Young Goalkeeper's Fracture: Radiographic Findings
The aim of this project is to evaluate retrospectively goalkeeper's fractures in children using the children fracture classification and to evaluate the distal radius tilt angle of the growth plate on plain radiographs of the…
- Trial name
- Goalkeeper (NCT02840188)
- Testing
- Radius tilt angle
- Where
- Switzerland
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Accidental Fall, Fall Injury
The Impact of Specifically Adapted Judo-based Training Program on Risk Factors for Falls Among Adults
This is a control study with a 2-group pretest-posttest design investigating the effects of a 10-week judo-inspired exercise program (Judo4Balance) for physical functions, self-efficacy, activity level, and fall techniques among…
- Conditions
- Accidental Fall, Fall Injury, Work-related Injury, Work Accident
- Trial name
- J4BA (NCT04294342)
- Testing
- Active Comparator: Participants in 10 week Judo Inspired Exercise program
- Where
- Sweden
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Dalarna University
HIV Infections
ADAPT-POL: Planned Parenthood Center of El Paso Adopting and Demonstrating the Adaptation of Prevention Techniques
This study will look at the following questions: Was there a significant difference in HIV prevention knowledge, risk reduction attitudes, norms, intentions, self efficacy, number of sexual partners, and incidence of unprotected…
- Trial name
- NCT00252083
- Testing
- Popular Opinion Leader
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cervix Cancer, Cervical Intraepithelial Neoplasia
Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial
The goal of the ScreenUrSelf trial is to increase cervical cancer screening attendance and compliance to follow-up by offering a first-void urine self-sampling alternative to women who are currently not participating in the…
- Conditions
- Cervix Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- ScreenUrSelf (NCT05996783)
- Testing
- Colli-Pee Small Volumes, Evalyn Brush
- Where
- Belgium
- Volunteers
- 48,000 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
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