Clinical trials: Preventive Intervention
Unsafe Sex, Risk-Taking
Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)
The study ANRS 174 Doxyvac is a clinical trial that will use Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex with Men and using oral TDF/FTC for HIV Pre-Exposure Prophylaxis (PrEP) and…
- Trial name
- DOXYVAC (NCT04597424)
- Testing
- Experimental: doxycycline, Bexsero® vaccine
- Where
- 9 sites in France
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
COVID-19
Hydroxychloroquine and Azithromycin as Prophylaxis for Healthcare Workers Dealing With COVID19 Patients
The main objective of this study is to assess the efficacy of the combination hydroxychloroquine and Azithromycin (HCQ and AZ) in reducing the infection risk among health care professionals in direct contact with COVID-19…
- Trial name
- MOPHYDA (NCT04354597)
- Testing
- HCQ & AZ
- Where
- Jordan
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Hussein Cancer Center
HIV Infections, HIV Seronegativity
HIV Prevention Preparedness Study
The purpose of this study is to provide researchers with information that will help them prepare for a future study to test the efficacy of two anti-HIV vaginal gels.
- Trial name
- NCT00048282
- Where
- 10 sites in South Africa, Tanzania and 1 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fall, Fall Injury
Testing the SNOWDROP Intervention: Using a Clinical Decision Support System and Patient Portal for Falls Prevention Among Older Patients in Primary Care
Falls are a leading cause of injuries among older patients. Medication use is a major risk factor for falls. Because we lack tools to assess individualized risks, general practitioners (GPs) struggle with fall-related medication…
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- SNOWDROP (NCT05611008)
- Testing
- CDSS, Patient Portal
- Where
- Netherlands
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Amsterdam
Noise Exposure, Noise-induced Hearing Loss
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are: 1.
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia
- Trial name
- NCT06729632
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Restorear Devices LLC
Acute Mountain Sickness (AMS)
Safety and Efficacy of T89 in Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)
Acute mountain sickness (AMS) is one of three syndromes of altitude illness. It is very common when people venture over 2500 meters altitude.
- Trial name
- NCT03552263
- Testing
- T89 capsule
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tasly Pharmaceuticals, Inc.
Childhood Obesity
The Optimising Family Engagement in HENRY (OFTEN) Study
This study will test whether parent engagement (recruitment, attendance) in a Childhood obesity prevention programme (HENRY) can be improved in local authorities randomised to receive an Optimisation intervention (in addition to…
- Trial name
- OFTEN (NCT02675699)
- Testing
- Optimisation + HENRY, HENRY as standard
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity, Adolescent, Eating, Healthy
Prevention of Eating Habits Associated With Obesity
This study evaluates the effectiveness of a Wise Intervention based on a values alignment approach to improve obesity-related eating habits in Spanish adolescents.
- Trial name
- NCT05865444
- Testing
- Values alignment wise intervention, Educational traditional intervention
- Where
- Spain
- Volunteers
- 591 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Rabies Pre-exposure Prophylaxis
One-visit Multi-site Intradermal Rabies Vaccination - Dose Finding
To determine optimum dose level for a single visit multidose intradermal injection of rabies vaccine with the aim to induce immunological memory in all subjects.
- Trial name
- NCT02276625
- Testing
- rabies vaccine
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Fasciculation, Succinylcholine
Median Effective Dose of Cisatracurium for the Prevention of Fasciculation Caused by the Injection of Succinylcholine
Succinylcholine is currently the only depolarizing neuromuscular blocker widely used in anesthesia induction and is the drug of choice for rapid sequential anesthesia induction.
- Trial name
- NCT05760976
- Testing
- Cisatracurium
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Sexual Violence
Effectiveness of an Online Intervention Using a Feminist Approach on Gender Equality Promotion and Sexual Violence Prevention in China
This paper presents the findings of a clustered randomized controlled trial (cRCT) that evaluated the effectiveness of an online feminist sexual health intervention among Chinese young adults, providing insights into the impacts…
- Trial name
- NCT06353308
- Testing
- Sexual Violence Prevention, Sexual health intervention
- Where
- Hong Kong
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sports Physical Therapy
Effect of Injury Prevention Program on Cricketers
The main aim of the study is to prevent the injuries during cricket.Total 60 players were included in the study. 20 players were in warm up group,20 players were in cool down group and 20 players in control group.Base line…
- Trial name
- NCT04017715
- Testing
- Experimental: warm up, Experimental: cool down, No intervention: control
- Where
- Pakistan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Riphah International University
HIV-1
Investigation of the Safety of an HIV-1 Vaccine Given Intra-muscularly and Intra-nasally to Healthy Female Subjects
This study is designed to investigate the safety and efficacy of a newly developed vaccine against HIV-1 in female healthy subjects.
- Trial name
- NCT01084343
- Testing
- MYM-V101
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mymetics Corporation
Postoperative Shivering, Cesarean Delivery
Intravenous Dexmeditomidine for Prevention of Spinal Anesthesia Induced Shivering.
Intraoperative and post operative shivering is a common problem encountered in operating rooms and recovery suites. Shivering under spinal anesthesia has an incidence of 40-60%.
- Trial name
- NCT05342376
- Testing
- Dexmedetomidine Hydrochloride, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
HIV, HIV Infections
Evaluation of an Integrated Economic Strengthening and HIV Prevention Program for Vulnerable Youth in South Africa
This study evaluates whether the integration of an Economic Strengthening program with an HIV-prevention education program produce synergistic effects on economic and health outcomes for South African youth ages 14-17 years old.
- Trial name
- ASPIRES (NCT02888678)
- Testing
- Economic Strengthening (Impumelelo), HIV Prevention Education (Vhutshilo 2.2)
- Where
- South Africa
- Volunteers
- 1,773 people, healthy volunteers welcome
- Sponsor
- FHI 360
Tooth Diseases, Tooth Wear
Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening
The goal of this clinical trial is to test the effects of prophylactic antibiotics in healthy individuals who are in need of surgical crown lengthening.
- Trial name
- SCLABP (NCT05925179)
- Testing
- Surgical crown lengthening, Augmentin
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biruni University
Knowledge, Attitudes, Practice, Risk Behavior
The Effect of a Safety Video on Ski and Snowboard School Program Participants in Calgary, Alberta
The main objective of the study is to investigate if a video intervention can help increase knowledge, decrease risky behaviours on the hill, and reduce injury risk in students who participate in ski and snowboard school…
- Conditions
- Knowledge, Attitudes, Practice, Risk Behavior, Injuries
- Trial name
- NCT03184779
- Testing
- Ski and Snowboard Safety Video
- Volunteers
- 2,348 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Influenza
Incidence of Influenza, Downstream Complications of Influenza & Hospitalizations in Elderly Vaccinated With Fluarix™
This study will investigate the incidence of influenza, disease and various possible downstream complications and hospitalizations or emergency room visits after routine annual vaccination of the elderly population with Fluarix™.
- Trial name
- NCT00306982
- Testing
- Fluarix
- Where
- 12 sites in Australia, Brazil
- Volunteers
- 1,524 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pre-Exposure Prophylaxis, Hiv
Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)
The aim of this study is to examine the effect of social media intervention on the use of pre-exposure prophylaxis (PrEP) by young men who have sex with men (YMSM) in the greater New Haven area.
- Conditions
- Pre-Exposure Prophylaxis, Hiv, Men
- Trial name
- NCT04417946
- Testing
- PrEP messages, Heath messages
- Where
- 2 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Yale University
Long-acting Injectable Cabotegravir for PrEP, Oral Pre-Exposure Prophylaxis (PrEP)
BetterInfo on Women's PrEP Choices and Outcomes in Malawi
The purpose of this study is to understand PrEP user choices, preferences and implementation impact of the roll-out of long-acting injectable PrEP alongside oral PrEP among women in Blantyre, Malawi.
- Trial name
- NCT07579754
- Testing
- Tracing Strategy
- Where
- Malawi
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.