Clinical trials: Prilocaine
Premature Ejaculation
A Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment of Premature Ejaculation
A phase I, single-center, double-blind, randomized, placebo-controlled, safety and pharmacokinetic study to evaluate systemic and local vaginal exposure to lidocaine and prilocaine and the metabolites, 2,6-dimethylaniline…
- Trial name
- NCT01184105
- Testing
- Intervention A, Intervention B
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Pain
EMLA Cream as Analgesic for Outpatient Gynecological Procedures
The goal of this clinical trial is to compare pain perception in the study participant population undergoing the following gynecological procedures: Intra Uterine Device (IUD) insertion, hysteroscopy, and endometrial biopsy and…
- Trial name
- NCT05970354
- Testing
- EMLA Cream, VersaPro Cream Base for Compounding
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Methemoglobinemia
Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics
To establish and compare maximum methemoglobin blood levels and times to maximum methemoglobin blood levels following the administration of the injectable local anesthetics prilocaine and lidocaine when used for dental treatment…
- Trial name
- NCT01402869
- Testing
- 4% prilocaine plain, 2% Lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Contraception
Comparative Safety and Efficacy of Vaginal Misoprostol Versus Lidocaine-prilocaine Cream in Levonorgestrel IUD Insertion
the aim of the present study is to compare the safety and Efficacy of vaginal misoprostol versus Lidocaine-prilocaine cream in reducing pain during levonorgestrel IUD Insertion in women delivered only by cesarean deliveries
- Trial name
- NCT04339348
- Testing
- vaginal misoprostol, Lidocaine-Prilocaine Topical cream
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anesthesia Efficacy
Anesthetic Efficacy of Liposomal Prilocaine in Maxillary Infiltration Anesthesia
This blinded randomized, crossover, three period study aim to evaluate the anesthetic efficacy of liposome-encapsulated 3% prilocaine compared to 3% plain prilocaine and 3% prilocaine with 0,03IU/mL felypressin, after 1.8mL…
- Trial name
- NCT01073371
- Testing
- Prilocaine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Anesthetic Effectiveness
Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to the tooth as a supplemental injection, works very well following a…
- Trial name
- NCT01567839
- Testing
- Mandibular buccal Infiltration injection
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Topical Anesthesia
Pharmacokinetic Study of Nanoencapsulated Gel of Lidocaine, Prilocaine and Combination of Lidocaine and Prilocaine
This trial evaluated the pharmacokinetic interaction between fixed doses of lidocaine (2.5%), prilocaine (2.5%) or the association of both (Nanorap®) in healthy volunteers. The drug safety and tolerability was also evaluated.
- Trial name
- NCT03441841
- Testing
- Lidocaine + Prilocaine, Lidocaine, Prilocaine
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galeno Desenvolvimento de Pesquisas Clínicas
IUD, Endometrial Biopsy
2.5% Lidocaine/2.5% Prilocaine Cream for IUD Insertion and Endometrial Biopsy
The aim of this study is to determine if 5g of self-administered topical 2.5% lidocaine/2.5% prilocaine cream, reduces pain during IUD insertion and/or endometrial biopsy.
- Trial name
- NCT07768059
- Testing
- 2.5% lidocaine/2.5% prilocaine topical cream, VersaPro Cream Base for Compounding
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Lidocaine Adverse Reaction, Prilocaine Adverse Reaction
Efficacy of a Topical Anesthetic Containing Lidocaine and Prilocaine in Treatment With CO2 Fractional Laser
This is a study aimed at evaluating the efficacy of a topical anesthesia (test product) compared to placebo in adult patients of phototypes I to III, with indication of treatment of CO2 fractional laser in the forehead.
- Trial name
- CO2 (NCT03366246)
- Testing
- Lidocaine / Prilocaine Cream
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Galeno Desenvolvimento de Pesquisas Clínicas
Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl
A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries.
To compare the effects of using different doses of intrathecal hyperbaric prilocaine 2% combined with fentanyl 25 µg in patients scheduled for a day-case lower abdominal and urologic surgery in the geriatric patient population.
- Trial name
- NCT05726968
- Testing
- Pilocaine 2% (1.5 ml) and 25 ug fentany
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Itch
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens
With this experiment, we want to use to investigate whether repeated application of EMLA cream as a tool to modulate non-histaminergic itching, which is produced using small needles from the plant mucuna pruriens (it is known…
- Trial name
- NCT04858360
- Testing
- Emla 1 hour, EMLA 3 hours, Vehicle cream for 1 hour
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aalborg University