Clinical trials: Prilocaine
Dental Anesthesia Efficacy
Anesthetic Efficacy of Liposomal Prilocaine in Maxillary Infiltration Anesthesia
This blinded randomized, crossover, three period study aim to evaluate the anesthetic efficacy of liposome-encapsulated 3% prilocaine compared to 3% plain prilocaine and 3% prilocaine with 0,03IU/mL felypressin, after 1.8mL…
- Trial name
- NCT01073371
- Testing
- Prilocaine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pain, Procedural (During Sternum Dressing on Infants), Arteriovenous Fistula
Cryotherapy for Reducing Fistula Puncture Pain in Hemodialysis Patients
People on hemodialysis need their arteriovenous fistula (a blood vessel access point) punctured with a needle three times a week, which can cause pain and worry.
- Conditions
- Pain, Procedural (During Sternum Dressing on Infants), Arteriovenous Fistula, Kidney Failure, Chronic
- Trial name
- CRYO-AVF (NCT07694271)
- Testing
- Usual Care (Room-Temperature Water Bag), Cryotherapy (Ice Pack), Lidocaine/Prilocaine Gel
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Medical University
Spinal for Caesarean Section
Effect of Prilocaine on Motor Block During Caesarean Section
To compare the effects of using intrathecal prilocaine combined with fentanyl on duration of motor block versus that of intrathecal bupivacaine combined with fentanyl in elective caesarean section.
- Trial name
- NCT06133881
- Testing
- prilocaine, bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Postpartum
Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain
Postpartum perineal pain is a very common complaint. It can have negative consequences for mother and child including disability in daily functioning for the mother; for example, it can interfere in taking care of her infant and…
- Trial name
- NCT03146000
- Testing
- lidocaine-prilocaine cream, meloxicam rectal suppository
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Assiut University
Pleural Effusion
Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis
The research aims to compare the efficacy of topical Pridocaine cream (lidocaine 2.5% and prilocaine 2.5%) and the standardized local lidocaine infiltration in pain management before pleurocentesis.
- Trial name
- NCT05984264
- Testing
- lidocaine 2.5% and prilocaine 2.5% cream in pain management before pleurocentesis.
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Assiut University
Fast Track Surgery
Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous Voiding
Background: In the context of day-case surgery, the optimal spinal anesthetic should give immediate and effective anesthesia for an appropriate period, followed by rapid regression of sensory and motor blocking, rapid bladder…
- Trial name
- NCT07262398
- Testing
- Prilocaine, Bupivacain
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Theodor Bilharz Research Institute
Lentigo
The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser
This study will conduct a split-face and -body randomized control trial to compare lidocaine 2.5%/prilocaine 2.5% topical anesthetic (LPTA), lidocaine 7%/tetracaine 7% topical anesthetic (LTTA), and placebo vechicle (PV) on…
- Trial name
- NCT02427724
- Testing
- lidocaine 2.5%/prilocaine 2.5% topical anesthetic, lidocaine 7%/tetracaine 7% topical anesthetic, Q-switched 532nm Laser
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy
Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers
The main objective of the study is to determine the safety and tolerability of repeated application of PSD502 to the glans penis in healthy male volunteers
- Trial name
- NCT00483990
- Testing
- PSD502
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Episiotomy Pain
The Effect of Lidocaine - Prilocaine Cream (EMLA) Versus Mepivacaine Infiltration on Pain Relief During And After Mediolateral Episiotomies
Included women were divided randomly into two groups: Group A: (n=100): women were subjected to application of EMLA® cream "Lidocaine-prilocaine cream (EMLAcream; Astra Zeneca, Basiglio, Italy is an entectic mixture of 2.5%…
- Trial name
- NCT03264586
- Testing
- Lidocaine-prilocaine cream, mepivacaine infiltration group, mediolateral episiotomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pain
EMLA Cream as Analgesic for Outpatient Gynecological Procedures
The goal of this clinical trial is to compare pain perception in the study participant population undergoing the following gynecological procedures: Intra Uterine Device (IUD) insertion, hysteroscopy, and endometrial biopsy and…
- Trial name
- NCT05970354
- Testing
- EMLA Cream, VersaPro Cream Base for Compounding
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Intrathecal Injection, Hyperbaric Prilocaine
Intrathecal Injection of Hyperbaric Prilocaine Versus Hyperbaric Bupivacaine for Cystoscopic Procedures
This study aims to compare the intrathecal injection of hyperbaric prilocaine 2% versus hyperbaric bupivacaine 0.5% in cystoscopy procedures.
- Conditions
- Intrathecal Injection, Hyperbaric Prilocaine, Hyperbaric Bupivacaine, Cystoscopic Procedures
- Trial name
- NCT07664618
- Testing
- Bupivacaine, Prilocaine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Pain
Topical Anesthetic Use In Pessary Management
The purpose of this study is to evaluate if lidocaine-prilocaine (EMLA 5%) cream can reduce pain and discomfort at the time of vaginal pessary removal and insertion.
- Trial name
- NCT02380742
- Testing
- lidocaine-prilocaine cream
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Loyola University
Combined Spinal Epidural Anesthesia, Prilocaine
Spinal Prilocaine for Caesarian Sections
Prilocaine theoretically could provide faster onset because of its lower pKa (7,7) compared to bupivacaine (8,1). The primary objective of this prospective double blind randomized trial is to determine block onset of spinal…
- Conditions
- Combined Spinal Epidural Anesthesia, Prilocaine, Bupivacaine, Pain
- Trial name
- NCT03219086
- Testing
- combined spinal epidural anaesthesia, Prilocaine, Bupivacaine
- Where
- 3 sites in Belgium
- Volunteers
- 182 people
- Sponsor
- University Hospital, Antwerp
Anesthesia, Spinal, Ambulatory Surgical Procedures
Spinal Anesthesia for Outpatient Abdominal Wall Surgery: Comparison of Bupivacaine, 2-chloroprocaine and Prilocaine
Considering fast-track principles, an ideal spinal anesthetic should have minimal complications and above all fast recovery so reducing in-hospital stay.
- Conditions
- Anesthesia, Spinal, Ambulatory Surgical Procedures, Hernia, Inguinal, Hernia, Umbilical
- Trial name
- spinal (NCT02813382)
- Testing
- Bupivacaine, Prilocaine, Chloroprocaine
- Volunteers
- 101 people
- Sponsor
- AZ St.-Dimpna Geel
Hemodynamic Instability
Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients
Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients…
- Trial name
- NCT06165679
- Testing
- Prilocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Surgery Scheduled
Evaluating the Effectiveness of Dermal Analgesia Provided by the Application of Lidocaine and Prilocaine Cream 5% on the Puncture Site of Axillary Blocks
Prospective Study, monocentric, controlled, randomized study. Evaluating the effectiveness of dermal analgesia provided by the application of Lidocaine and Prilocaine Cream 5% on the puncture site of axillary blocks.Our study…
- Trial name
- NCT01673542
- Testing
- Lidocaine-Prilocaine 5%, DEXERYL
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Poitiers University Hospital
Anesthesia, Local, Photodamaged Skin
Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face
The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.
- Conditions
- Anesthesia, Local, Photodamaged Skin, Topical and Infiltration Anesthetic Toxicity
- Trial name
- NCT04523961
- Testing
- 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion, 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Time to First Void After Spinal Anaesthesia
Using Three Different Doses of Hyperbaric Prilocaine 2% Local Anaesthetic ( 40,50 and 60mg ),Through Spinal Anaesthesia in Knee Arthroscopy Patients to Compare Time to Void
The goal of this randomised trial is to use a short acting local anaesthetic drug (hyperbaric prilocaine 2%) which is beneficial in short operations which are performed as a day case surgery.
- Trial name
- Prilocaine (NCT06703580)
- Testing
- Hyperbaric prilocaine 2% 40 mg, hyperbaric prilocaine 2% 50 mg, hyperbaric prilocaine 2% 60 mg
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Procedural Pain Relief
Needle Procedures Success Rate After Application of Ralydan vs EMLA in Children
Needle-related procedures are among the most common sources of pain and distress for children in the health care setting. More than 50% of children reported pain during these procedures.
- Trial name
- NCT02519660
- Testing
- Lidocaine/Tetracaine patch, Lidocaine/Prilocaine cream
- Where
- 3 sites in Italy
- Volunteers
- 339 people
- Sponsor
- IRCCS Burlo Garofolo
Tattoo, Acne Keloidalis Nuchae
7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream
The purpose of this study is to compare the efficacy of 7% lidocaine / 7% tetracaine cream and 2,5% lidocaine / 2,5% prilocaine cream in reducing self-reported pain during a single laser procedure in the treatment of acne…
- Trial name
- OPTICA (NCT02372786)
- Testing
- 2,5% lidocaine / 2,5% prilocaine cream, 7% lidocaine / 7% tetracaine cream, Neodymium-doped yttrium aluminium garnet (Nd:Yag) laser
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center