Clinical trials: Primary Care
Papillomavirus Vaccines
Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination
Each year the human papillomavirus (HPV) causes 30,000 cancers in the United States despite the availability of very effective and safe vaccines.
- Trial name
- NCT03501992
- Testing
- Current care, Reminder-recall, Audit-and-feedback
- Where
- United States
- Volunteers
- 9,242 people
- Sponsor
- Mayo Clinic
Autism Spectrum Disorder
Partnering With Autistic Adults to Improve Healthcare
The goal of this proposal is to develop and evaluate patient-centered care tools for autistic adults and their primary care providers (PCPs).
- Trial name
- NCT01579669
- Testing
- Use of toolkit
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Oregon Health and Science University
Chronic Pain
Digital Therapeutic for Chronic Pain Feasibility Study
The investigators will conduct a 2-arm randomized control feasibility study to evaluate: 1) the feasibility of using the mobile app and an optional activity tracker, 2) the feasibility of conducting a 2-arm trial, and 3) estimate…
- Trial name
- NCT06000007
- Testing
- 2Morrow Chronic Pain Self-Management Program - digital therapeutic mobile app, Treatment as usual
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Washington
Chronic Disease, Multi-morbidity
Minnesota Care Coordination Effectiveness Study
Medical care has improved greatly over the past 50 years. Treatments for most medical conditions can help us lead longer and healthier lives, but there are still problems.
- Conditions
- Chronic Disease, Multi-morbidity, Care Coordination
- Trial name
- MNCARES (NCT04957979)
- Testing
- Nursing/Medical Model of Care Coordination, Medical/Social Model of Care Coordination
- Where
- 3 sites in United States
- Volunteers
- 25,507 people
- Sponsor
- HealthPartners Institute
Asthma
The Electronic Asthma Action Plan System for Implementation in Primary Care
Asthma is a common and potentially fatal chronic disease. An asthma action plan (AAP) is a written plan produced by a physician for a patient with asthma, to provide education and guidelines for self-management of worsening…
- Trial name
- eAAPS (NCT01070095)
- Testing
- Electronic Asthma Action Plan System
- Where
- 3 sites in Canada
- Volunteers
- 19 people
- Sponsor
- Unity Health Toronto
Type 2 Diabetes Mellitus, Prediabetic State
Opportunistic Screening for Prediabetes and Early Diabetes in Primary Care
People who might have prediabetes or unrecognized diabetes will be screened for these problems at an outpatient visit. For screening, they will take a sugary drink containing 50 grams of glucose, and have a blood sample one hour…
- Trial name
- NCT00787839
- Testing
- Glucose challenge test, Glucose tolerance test
- Where
- United States
- Volunteers
- 1,939 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Sleep, Sleep Disturbance
Sleep Promotion Program Primary Care (SPP PC) Open Trial
Investigators developed a brief, scalable, behavioral Sleep Promotion Program (SPP) for adolescents with short sleep duration and sleep-wake irregularity, which relies on one individual session and smart phone technology to…
- Conditions
- Sleep, Sleep Disturbance, Insufficient Sleep
- Trial name
- SPP OT (NCT06239792)
- Testing
- Sleep Promotion Program
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea of Adult, Insomnia
Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study
Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study (SMART DOCS) was designed to develop and evaluate a new approach (patient-centered outcomes and coordinated-care management [PCCM]) for the…
- Conditions
- Obstructive Sleep Apnea of Adult, Insomnia, Circadian Rhythm Sleep Disorder, Sleep Related Movement Disorders
- Trial name
- SMART DOCS (NCT02037438)
- Testing
- CONV care for the diagnosis and treatment of sleep disorders, PCCM for the diagnosis and treatment of sleep disorders
- Where
- United States
- Volunteers
- 1,836 people
- Sponsor
- Stanford University
Hazardous Drinking, HIV
Brief Alcohol Intervention for HIV-Infected Men Who Have Sex With Men (MSM) in a Primary Care Setting
This is a randomized clinical trial to examine the effects of a brief counseling intervention for heavy drinking HIV-infected men who have sex with men compared to HIV care as usual.
- Trial name
- NCT01328743
- Testing
- Brief alcohol intervention
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Brown University
Acceptability of Health Care, HIV Primary Infection
A Multicomponent Intervention to Address Gender-based Violence in HIV
This project seeks to adapt and pilot a trauma-informed combination intervention named 'Kickin' it with the Gurlz' that was designed with, for, and by transgender women of color to improve HIV prevention continuum outcomes.
- Trial name
- NCT04799197
- Testing
- Kicking it with the Gurlz
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cervical Cancer, Papillomavirus Infection
HPV Self-Sampling in Somali Women (Isbaar Project)
This study plans to assess the effect of implementing HPV self-sampling in primary care on uptake of cervical cancer screening in 30-65 year old Somali women who are due for cervical cancer screening.
- Conditions
- Cervical Cancer, Papillomavirus Infection, Uterine Diseases, Uterine Cervical Disease
- Trial name
- Isbaar (NCT05453006)
- Testing
- COPAN 552c.80 FLOQSwab
- Where
- United States
- Volunteers
- 3,367 people
- Sponsor
- University of Minnesota
Opioid-use Disorder, Mental Health Disorder
Collaborating to Heal Addiction and Mental Health in Primary Care
The gold-standard intervention for Opioid Use Disorder (OUD) is Medication for Opioid Use Disorder (MOUD). Because more patients with OUD need access to MOUD in primary care, the investigators are testing whether the…
- Trial name
- CHAMP (NCT04600414)
- Testing
- Collaborative Care for Mental Health Symptoms, Collaborative Care for Opioid Use Disorder and Mental Health Symptoms
- Where
- 33 sites in United States
- Volunteers
- 254 people
- Sponsor
- University of Washington
Addiction
Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings
This study will develop a clinical decision support tool that assists primary care providers in carrying out substance use interventions, and then compare (in Phase 2) two clinical scenarios, screening only (SO) vs.
- Trial name
- NCT02893514
- Testing
- Screening Only (SO) condition, SUSIT Condition
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acute Upper Respiratory Tract Infections
Trial of Post-Dated Delayed Antibiotic Prescriptions
Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral). This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2…
- Trial name
- NCT02732847
- Testing
- A delayed prescription dated 2 days after clinical office visit, Usual Dated
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- Memorial University of Newfoundland
Child Behavior Problems
Parent Program to Improve Child Behavior Problems
The purpose of this research study is to learn whether or not a brief parenting program called Child Adult Relationship Enhancement (CARE) offered at a primary care office can help improve behavior problems in children who are…
- Trial name
- NCT02049749
- Testing
- Immediate CARE
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effectiveness of Telemedicine in Primary Care
Leveraging a natural experiment approach, the investigators will examine rapidly changing telemedicine and in-person models of care during and after the COVID-19 crisis to determine whether certain patients could safely choose to…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes
- Trial name
- NCT04684836
- Testing
- Exposure to telemedicine, after the onset of the pandemic
- Where
- 4 sites in United States
- Volunteers
- 33,100 people
- Sponsor
- Weill Medical College of Cornell University
Myocardial Infarction, Multivessel Coronary Artery Disease
Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD.
The Compare-Acute trial is a prospective randomised trial in patients with multivessel disease, who are admitted into hospital with a ST-elevation Myocardial Infarction.
- Trial name
- CompareAcute (NCT01399736)
- Testing
- FFR-guided revascularisation strategy, randomised to guidelines group
- Where
- 26 sites in Czechia, Germany and 6 more
- Volunteers
- 885 people
- Sponsor
- Maasstad Hospital
Weight Loss
Impact of Volunteer Peer-Led Intervention for Weight Control in Primary Care
The specific objective of this research proposal is to determine the short-term efficacy of a primary care-based weight control intervention in which successful volunteer peers deliver a group-based program.
- Trial name
- KL2 (NCT01850550)
- Testing
- Weight loss Groups
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking Cessation
A Text Messaging Program for Smokers in Primary Care
This study is a four arm pilot randomized controlled trial testing the effect of a 12 week text messaging intervention and a mailed nicotine medication intervention, alone and in combination to a control condition consisting of…
- Trial name
- GR2Q (NCT03174158)
- Testing
- Mailed nicotine replacement therapy, Text messaging, Brief advice
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Massachusetts General Hospital
Hypertension,Essential, White Coat Hypertension
Implementing Hypertension Screening Guidelines in Primary Care
The goal of this study is to use a cluster-randomized design (1:1 ratio) among 8 primary care clinics affiliated with New York-Presbyterian Hospital to test the effectiveness of a theory-informed multifaceted implementation…
- Trial name
- EMBRACE (NCT03480217)
- Testing
- Multifaceted Implementation Strategy, Usual care
- Where
- 2 sites in United States
- Volunteers
- 1,186 people
- Sponsor
- Columbia University