Clinical trials: Primary Neoplasm
Breast Neoplasm
GenetiKiT: Evaluation of an Educational Intervention on the Delivery of Genetics Services by Family Physicians
There is an urgent need for a knowledge translation strategy to facilitate the integration of genetics into family medicine, to improve the low knowledge base of most Canadian family physicians, ensure that the needs are met of…
- Trial name
- NCT00295529
- Testing
- Multifaceted educational intervention
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Motor Competence, Physical Activity, Balance
Effects of a Structured Motor Development Program Using Traditional Games on Motor Competence, Balance, Physical Activity Self-Efficacy, and Physical Activity Enjoyment in Primary School Children: A School-Based Randomized Controlled Trial
This randomized controlled trial aims to evaluate the effects of a 10-week structured motor development program based on traditional Turkish children's games on motor competence, balance performance, physical activity…
- Trial name
- TradGamesRCT (NCT07721831)
- Testing
- Traditional Turkish Children's Games Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ozlem Sinem USLU
Childhood Cancer, Childhood Cancers
Examination of the Relationship Between Quality of Life and Caregiving Burden Among Caregivers of Pediatric Oncology Patients
Primary Aim The primary aim of this study is to determine the quality of life and caregiving burden levels of caregivers of pediatric oncology patients and to examine the relationship between these two variables.
- Conditions
- Childhood Cancer, Childhood Cancers, Caregiver Subjective Burden, Primary Caregivers of Children Newly Diagnosed With Cancer
- Trial name
- NCT07308301
- Testing
- Assessment of caregiver quality of life and burden
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Fatma Beyza Akdeniz
Headache Disorders, Primary, Migraine
Trigeminal Brainstem Mapping
To what extent the somatotopy of the 3 branches of the trigeminal nerve (V1,V2,V3) as well as the greater occipital nerve (GON) in the brainstem but also in the thalamus and the insula can be mapped using functional imaging and…
- Trial name
- NCT03999060
- Testing
- Electric Current Stimulation
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Primary Raynaud's Phenomenon (PR), Genetic Mutations Causing PR
Prospective Multicenter Study on the Identification of Genetic Abnormalities Predisposing to Vasospasm From a Privileged Model: the Primary Raynaud's Phenomenon
Vasospasm is a transient contraction causing a decrease in caliber of a vessel and thus a decrease in vascularization in a vascular territory leading to suffering of tissue in the sector concerned.
- Conditions
- Primary Raynaud's Phenomenon (PR), Genetic Mutations Causing PR, Study of Patients and Their Relatives (With or Without Primary PR)
- Trial name
- RAY-GENE (NCT02202291)
- Testing
- Demonstration of genetic mutations causing Raynaud's phenomenon
- Where
- 6 sites in France
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Chronic Obstructive Pulmonary Disease
Evaluation of an AR-Assisted System for Standardizing Spirometry
Spirometry is the gold-standard tool for diagnosing Chronic Obstructive Pulmonary Disease (COPD). However, its implementation in primary care is often limited by a shortage of qualified technicians and inconsistent testing…
- Trial name
- NCT07440420
- Testing
- AR-Assisted Spirometry Guidance System, Routine Technician-led Spirometry Guidance
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Normal Physiology, fMRI
The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans
Background: Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning.
- Trial name
- NCT01260740
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Effectiveness of an Adventure-based Training Programme
This study tested the effectiveness of an adventure-based training programme in promoting the psychological well-being of primary schoolchildren.
- Trial name
- NCT02517450
- Testing
- an adventure-based training programme
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Headache, Migraine
Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
In this study the investigators will research the hypothesis that the drug Acetazolamide induce headache and dilation of cerebral arteries and increase the cerebral blood flow in the areas of the brain supplied by these arteries.
- Trial name
- NCT01750723
- Testing
- Acetazolamide
- Where
- 2 sites in Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Diphtheria, Tetanus
Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age
This is a phase II, randomized, double-blind, active-controlled, parallel-group, multicenter study to evaluate the immunogenicity and safety of DTaP-HepB-IPV-Hib hexavalent vaccine LR20062 in healthy infants as primary series at…
- Conditions
- Diphtheria, Tetanus, Pertussis, Hepatitis B
- Trial name
- NCT06618196
- Testing
- LR20062, DTaP-HepB-IPV-Hib vaccine
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- LG Chem
Colorectal Cancer
Colorectal Cancer Screening in Chinese Rural Communities
Colorectal cancer (CRC) is one of the most common malignant neoplasms significantly impacting population health and longevity. With the transformation of lifestyle and dietary patterns among Chinese residents, coupled with an…
- Trial name
- SMART-CRC (NCT07180303)
- Testing
- Remote training courses covering the latest CRC screening guidelines, identification of high-risk individuals and their standard of care, and dietary intervention strategies. Ongoing support services,, Continuation of routine healthcare services without any additional training interventions.
- Where
- China
- Volunteers
- 20,026 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
COVID-19
Study of HS-10517 in Chinese Adult Participants
A Phase I/II, randomized, double-blind, placebo-controlled study to evaluate safety, tolerability, pharmacokinetics and primary efficacy of HS-10517 in Chinese adult participants.
- Trial name
- NCT05779579
- Testing
- HS-10517 Dose 1, HS-10517 Dose 2, HS-10517 Dose 3
- Where
- China
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Suicide and Depression, Psychological Distress
Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population
An interventional research study will be undertaken to assess the effectiveness of the promotion at the local level of an e-health tool for suicide and psychological distress prevention (the StopBlues application and website).
- Conditions
- Suicide and Depression, Psychological Distress, Anxiety Disorders, Local Authorities Promotion
- Trial name
- PRINTEMPS (NCT03565562)
- Testing
- Promotion of the e-health tool by local authorities, Promotion of the e-health tool by local authorities and GPs
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Human Immunodeficiency Virus, Substance Use
Harm Reduction in HIV Primary Care for PLWH Who Use Drugs
People living with HIV (PLWH) who use drugs experience significant health disparities including lower rates of retention in HIV care and higher rates of unsuppressed viral load, resulting in secondary infections and increased…
- Conditions
- Human Immunodeficiency Virus, Substance Use, Stigma, Social
- Trial name
- NCT05404750
- Testing
- Harm Reduction
- Where
- 3 sites in United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Infections, Risk Reduction
Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
PrEP (pre-exposure prophylaxis) is an effective prevention strategy in which HIV-negative individuals take antiretroviral drugs (tenofovir disoproxil fumarate and emtricitabine - TDF/FTC) to reduce HIV acquisition.
- Conditions
- HIV Infections, Risk Reduction, Risk Behavior, Risky Health Behavior
- Trial name
- Seroincidence (NCT05674682)
- Testing
- HIV testing
- Where
- 2 sites in Brazil
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Migraine Disorders
Trigeminal Brainstem Mapping 2: Higher Cortical Strucureas as Well as Subnuclei of the Spinal Trigeminal Nucleus
In previous studies clustering of the three branches of the trigeminal nerve in brainstem were shown, cerebellum and periaqueductal gray.
- Trial name
- NCT06535880
- Testing
- Electric Current Stimulation
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
In this study, we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression.
- Conditions
- Autoimmune Hepatitis, Primary Sclerosing Cholangitis, Non-Alcoholic Fatty Liver Disease, Liver Abscess
- Trial name
- LGAS (NCT06519162)
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital
Fibromyalgia, Fibromyalgia, Primary
Understanding Health Services Delivery for Fibromyalgia
This research study aims to: i) Explore and understand how health and social care for people with fibromyalgia living in the UK is organised and delivered.
- Conditions
- Fibromyalgia, Fibromyalgia, Primary, Fibromyalgia, Secondary
- Trial name
- NCT04771260
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
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