Clinical trials: Primary Teeth
Pulp Therapy, Pulpitis - Irreversible
Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp
Preserving primary teeth until their normal exfoliation time is crucial for maintaining the child's normal function, esthetics, arch integrity, and correct eruption of permanent successors.
- Conditions
- Pulp Therapy, Pulpitis - Irreversible, Pulp Necrosis
- Trial name
- NCT07230717
- Testing
- Pulpotomy, Pulpectomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Pulpotomies Primary Teeth
Effect of Local Anesthesia Techniques on Pulp Hemostasis in Primary Molars
The goal of this clinical trial is to compare the effects of two local anesthesia techniques on pulp hemostasis time during pulpotomy treatment of mandibular primary molars in children aged 6-9 years.
- Trial name
- NCT07810452
- Testing
- Inferior Alveolar Nerve Block Anesthesia, Computer-Controlled Intraosseous Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Silver Diamine Fluoride
Clinical Effectiveness and Parental Acceptance of Silver Diamine Fluoride in Preschool Children: A Non-randomized Trial
Silver diamine fluoride (SDF) is a topical fluoride agent that has emerged in recent years and has a strong potential to arrest dentinal caries in early childhood caries.
- Trial name
- NCT06293547
- Testing
- Silver Diamine Fluoride
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pulpitis
A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies
Internal resorption in the most common cause of failure in FS pulpotomies in primary molars. This has been attributed to the release of free eugenol from the zinc and eugenol mixture of the base material over the pulp tissue.
- Trial name
- NCT05557812
- Testing
- non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies, eugenol based zinc oxide and Ferric Sulfate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pulpotomy, Tooth, Deciduous
Biodentine Partial Pulpotomy of Pulpally Exposed Primary Molars
Objective: To compare success rates of biodentine partial pulpotomy versus formocresol pulpotomy treatment of pulpally exposed lower primary molars.
- Trial name
- NCT02393326
- Testing
- partial pulpotomy with biodentine, Formocresol pulpotomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Direct Pulp Capping in Primary Teeth
DPC in Primary Molars.
To evaluate clinical and radiographical outcomes of direct pulp capping using calcium hydroxide (CH), mineral trioxide aggregate (MTA), and premedicated direct pulp capping (PDPC) with formocresol (FC) in primary teeth.
- Trial name
- NCT05222243
- Testing
- Direct pulp capping with calcium hydroxide, Direct pulp capping with MTA, Direct pulp capping with Formocresol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries
Impact of Detecting Initial and Active Caries Lesions in Primary Teeth
The present study aims to evaluate the impact of detecting active initial caries lesions in primary teeth regarding effectiveness, cost-effectiveness, applicability (acceptability and satisfaction) and quality of life.
- Trial name
- NCT02473107
- Testing
- Advanced caries lesions detection (no activity assessment), All caries lesions detection (+activity assessment)
- Where
- Brazil
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries, Tooth Decay
Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary anterior teeth.
- Trial name
- NCT06354647
- Testing
- Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Deep Caries, Indirect Pulp Capping
Pulp Capping in Primary Molars Using TheraCal (LC)
A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base…
- Conditions
- Deep Caries, Indirect Pulp Capping, Direct Pulp Capping, Reversible Pulpitis
- Trial name
- NCT05167123
- Testing
- Light cured tri-calcium silicate base material
- Where
- 3 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Primary Teeth
Clinical Evaluation of Compomer and Composite Class II Restorations in Primary Molars: 24 Months Results
It was aimed to evaluate the clinical performance of resin-hybrid composite and compomer materials in primary molars over a 2-year period.
- Trial name
- NCT04678141
- Testing
- Dyract XP (Dentsply De Trey), Kerr Herculite Classic (Kerr Corporation),R&D Series NOVA(Kuraray Medical Inc) Clearfil TM SE Bond (Kuraray Medical),Hydrocal LC (Medicept Dental)
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Sensitivity, Tooth
Efficacy of Tooth Bleaching With 35% and 6% Hydrogen Peroxide in Primary Dentition
The aesthetics of dental elements generates great psychological and social impacts, both in the deciduous and permanent dentition. One of the techniques widely used to visually improve the appearance of teeth is bleaching.
- Trial name
- NCT05789004
- Testing
- Tooth Bleaching with Whiteness HP Automixx 35%, Tooth Bleaching with Whiteness HP Automixx 6%
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pulpotomy, Dental Caries
Comparison of Biodentine and MTA Pulpotomies in the Primary Molar Teeth 3 Year Follow up
The aim of this study is to compare two pulpotomy medicaments in primary molars clinically.A total of 200 primary molars with deep caries were treated with two different pulpotomy medicaments (Mineral Trioxide Aggregate and…
- Trial name
- NCT03395496
- Testing
- Biodentine, ProRoot (Aggregate)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Apical Periodontitis, Postoperative Pain
Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic Infections
The aim of this study is to evaluate the effects of cryotherapy applications on the inflammatory cytokine and collagenase matrix metalloproteinase levels during root canal treatment and postoperative pain intensity and incidence.
- Conditions
- Apical Periodontitis, Postoperative Pain, Cytokine Levels
- Trial name
- NCT04798144
- Testing
- Distilled water irrigation kept at 2.5°C degree, Distilled water irrigation kept at room temperature
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Dental Caries in Children
Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth
A clinical trial to evaluate a filling material (ACTIVA) and compare it to a traditional filling material (compomer) to restore decayed deciduous teeth in children
- Trial name
- NCT03516838
- Testing
- ACTIVA™ BioACTIVE, Compomer
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Ghent
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial
This study is a randomized controlled clinical trial on primary anterior teeth of 3-5 year-old patients suffering from white spot lesions (ICDAS system II scores 1-2).
- Trial name
- NCT03927794
- Testing
- Self-Assembling Peptide P11-4
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cleft Palate
Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth
This study aimed to evaluate clinically the "Alveolar extension" technique for palatoplasty in cases of primary closure of cleft palate regarding its effect on: 1. Eruption of Primary dentition. 2.
- Trial name
- NCT05286398
- Testing
- Palatoplasty, Addition silicone impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Pulpotomy
BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars
The objective of this clinical study was to prospectively compare the clinical and radiographic success rates of BiodentineTM pulpotomies versus formocresol pulpotomies in children vital primary molars.
- Trial name
- NCT03779698
- Testing
- BiodentineTM, Formocresol
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Premature Loss of Primary Molars, Space Maintenance
Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning
This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years.
- Conditions
- Premature Loss of Primary Molars, Space Maintenance, Dental Arch Development, Pediatric Tooth Extraction
- Trial name
- NCT06965777
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University