Clinical trials: Primary Teeth
Dental Caries
Use of Fissure Sealants on Primary Molars
Sealants have been shown to be the most effective caries preventive measure in permanent dentition. Sealants of the primary molars soon after they erupt would reduce the total caries experience of the primary teeth of the…
- Trial name
- NCT01438866
- Testing
- Fissure sealant, Fissure sealants and fluoride varnish
- Where
- Kuwait
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Primary Dental Caries
Effects of Partical Excavation in One Versus Two Procedures of Primary Deep Caries (PAPRICA)
Background: Deep caries is the most frequent reason for performing root canal treatments. Minimally invasive methods for the treatment of deep carious lesions might therefore be relevant to avoid pulp exposures and consequently…
- Trial name
- PAPRICA (NCT03696498)
- Testing
- Resin restoration (1 step), Resin restoration (2 steps)
- Where
- 11 sites in Denmark, Lithuania and 2 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
White Spot Lesion
Remineralization Effect Of Egg Shell Versus Fluoride Varnish On Early Carious White Spot Lesions In Primary Teeth
The goal of this clinical trial is to to assess the remineralization potential of Egg shell hydrogel versus fluoride varnish in early carious white spot lesions in anterior primary teeth.
- Trial name
- NCT06932926
- Testing
- Egg shell hydrogel, Fluoride varnish
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities
The study is a randomized controlled trial aiming to compare the effectiveness of Silver modified atraumatic restorative technique and (SMART) and conventional atraumatic restorative technique (ART) regarding their caries…
- Trial name
- NCT03881020
- Testing
- Silver diamine Fluoride 38%, Conventional atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries in Children
Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish
To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.
- Trial name
- NCT03557996
- Testing
- Silver Diamine Fluoride, Sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Dental Caries
Primary Care Beverage Study
This is a pilot randomized clinical trial of a brief educational intervention offered in primary care for Latino parents that promotes healthy beverage consumption by infants and toddlers.
- Trial name
- NCT02257203
- Testing
- Sugar Sweetened Beverage Education, Reading Education
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars
Dental caries is one of the most prevalent chronic diseases in people worldwide. Traditional clinical treatment of dental decay has developed on the basis of the removal of carious tissues with high-speed handpieces and…
- Trial name
- NCT05427591
- Testing
- The chemomechanical caries removal agent "BRIX3000®" in group (1A), The traditional surgical treatment in group (1C), The chemomechanical caries removal agent "Carie-CareTM" in group (2B)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Preschool Children, Dental Caries in Primary Teeth
A Comparison of Teledentistry vs Clinical Examination for Treatment Needs Assesment
Dental caries is one of the most common chronic diseases in children and may require complex dental treatment, especially in preschool-aged children.
- Trial name
- NCT07625982
- Testing
- Tele- dentistry intraoral exam
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Irrigation Activation, Endodontic Disease
Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction
This in-vivo study aim to evaluate effect of different irrigation activating techniques on Irrigant Penetration Depth and Microbial Reduction in root Canals
- Trial name
- NCT06660797
- Testing
- Group1: A matching gutta-percha master cones will be used in up and down motion 2mm amplitude at a frequency of 100 strokes during approximately 1 min in each prepared canal., Group2: XP-endo Finisher activation: The XP-endo Finisher instrument will be used in continuous rotation for 1 mintute, Group 3:EasyClean system activation : EC instrument coupled to the countrangle handpiece and operated with a micromotor at approximately 20,000 rotations per minute in continuous rotation.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Endodontically Treated Teeth
Influence of Working Length Methods in the Performance of Pulpectomies in Primary Teeth
Verify, through a randomized double-blinded clinical trial, the influence in the performance of pulpectomies in primary teeth, based on two working length methods, electronic and radiographic.
- Trial name
- NCT03161639
- Testing
- Pulpectomies
- Where
- 2 sites in Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Pulpitis - Irreversible, Ozone
Zinc Oxide Ozonated Olive Oil in LSTR
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair…
- Conditions
- Pulpitis - Irreversible, Ozone, Pulp Disease, Dental, Primary Teeth
- Trial name
- Zn-OO/MTAP (NCT06854744)
- Testing
- lesion sterlization and tissue repair, Zinc Oxide Ozonated Oil, Modified Triple Antibiotic Paste
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Fissure Sealant
The Effect of Different Deproteinizing Agents on the Clinical Success of Fissure Sealants in Primary Teeth
Investigation of the effect of deproteinization agents on the clinical success of non-invasive fissure sealant application, which is a non-invasive method used to prevent caries formation or to stop the progression of initial…
- Trial name
- NCT07003958
- Testing
- application of deproteinization agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Dental Caries in Children, Wound Heal
Biostimulation After Tooth Extraction
This study evaluated the effect of low-level laser therapy on postoperative pain and wound healing in children undergoing primary molar extractions 40children, 6-10 years of age, systemically healthy, and had atraumatic…
- Trial name
- NCT06018584
- Testing
- Tooth extraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hazal Özer
Tooth Decay, Tooth Restoration
Clinical and Radiographic Evaluation of Two Matrix Systems for Restoration of Class II Cavities in Primary Molars
this study aims to evaluate and compare the clinical and radiographical efficacy, operator ease, satisfaction and patient comfort in restoring class II cavities in primary molars using Fender Mate system with T-band system.
- Trial name
- NCT06447324
- Testing
- Fender Mate matrix system, T-band matrix
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aswan University
Periapical Abscess
Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy
The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy…
- Trial name
- NCT02943759
- Testing
- Neem leaf extract, Chlorhexidine gluconate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Primary Tooth Pulpotomy, Vital Pulp Therapy
Evaluation of the Success of TheraCal PT in Pulpotomy Treatment of Primary Teeth Using Low-Level Laser Therapy
This randomized clinical study aimed to compare the clinical and radiographic outcomes of TheraCal PT and Biodentine in pulpotomy treatment of primary teeth and to evaluate the influence of low-level laser therapy (LLLT) on…
- Trial name
- NCT07276685
- Testing
- Biodentine Pulpotomy, Low-Level Laser Therapy + Biodentine, TheraCal PT Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NECIBE DAMLA ŞAHIN
Dentist's Role
Two Preventive Measures on Caries Progression in Mixed Dentition Patients.
Primary Objective: Assessing the clinical effect of SDF and Laser on the prevention of initial caries progression with and without pits and fissure sealants in both permanent and primary molars.
- Trial name
- NCT06119126
- Testing
- SDF1, Diode Laser, Pit Fissure Sealant
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Dental Caries
Clinical and Radiographic Evaluation of Silver Diamine Fluoride Versus Light-Cured Silver Diamine Fluoride in Carious Primary Molars
This randomized clinical trial aims to evaluate and compare the clinical and radiographic performance of 38% silver diamine fluoride (SDF) with 38% silver diamine fluoride followed by light curing in children with carious primary…
- Trial name
- NCT07903155
- Testing
- Silver diamine Fluoride 38%, LED light curing
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Displaced Tooth
Assessment of Extraction of Primary Canines in Treating Mesioangular Displaced Permanent Canines
This research project is important because there is no gold standard to rely on regarding the effect of the extraction of primary canines as an interceptive treatment for children with mesioangular displaced canines.
- Trial name
- NCT03684525
- Testing
- Extraction of primary canines
- Where
- Saudi Arabia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University