Clinical trials: Probiotic
Healthy Young Adults
Exploring Wellbeing Outcomes in Adolescents Using Bifidobacterium Longum, 1714™
The purpose of this study is to evaluate changes in self-reported wellbeing outcomes in adolescents. Bifidobacterium longum, 1714™ has previously been associated with beneficial effects on stress-related outcomes, sleep quality…
- Trial name
- NCT07752342
- Testing
- Bifidobacterium longum, 1714™
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Novonesis
Periodontal Diseases, Smoking
Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy
It is a clinical trial conducted on smokers with chronic periodontitis in which the participants are divided into two groups and one group is provided with antibiotics while the other with probiotics as an adjunct to non-surgical…
- Trial name
- NCT04209777
- Testing
- Probiotic Blend Chewable Tablet, Antibiotics
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Healthy, Overweight
The Influence of Probiotics on Body Weight and Composition
The purpose of this study is to evaluate the addition of two different probiotic interventions to a comprehensive behavioral lifestyle intervention on body weight loss and overall health in overweight adults.
- Trial name
- WLP (NCT02465294)
- Testing
- Probiotic, Behavioral lifestyle intervention, Blood Test
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Irritable Bowel Syndrome
The Effect of Probiotics on Symptoms and Intestinal Flora in Patients With Irritable Bowel Syndrome
To demonstrate benefit of a probiotic product in adults with irritable bowel syndrome.
- Trial name
- NCT02108119
- Testing
- Probiotics
- Where
- Netherlands
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Probi AB
Healthy
Evaluation of Bacillus Subtilis R0179 in Healthy Young Adults
The purpose of this study is to evaluate the effect of three doses of the probiotic B. subtilis (Bacillus subtilis R0179) delivered in capsules on gastrointestinal and general wellness in healthy young adults, survival through…
- Trial name
- NCT01802151
- Testing
- B. subtilis R0179
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Florida
Celiac Disease in Children
Celiac Disease Prevention With Probiotics
Background/Aim: Celiac disease is a common immune-mediated disorder, and the only currently available treatment is a gluten-free diet.
- Trial name
- CiPP (NCT03176095)
- Testing
- Probiotic
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Lund University
Constipation
Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit
This randomized, double-blind, controlled clinical trial among healthy volunteers with infrequent bowel movements but not severe constipation evaluate the effects of a supplementation in "symbiotic" on intestinal transit of…
- Trial name
- NCT04304170
- Testing
- VES002
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CEN Biotech
Hypertension, Cardiovascular Diseases
Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )
Nitric Oxide (NO) is an important molecule that is produced naturally in the body and that helps maintain healthy blood flow. Low availability of NO contributes to many diseases while administration of NO is therapeutic.
- Conditions
- Hypertension, Cardiovascular Diseases, Diabetes
- Trial name
- OPEDNPN (NCT06375694)
- Testing
- Herbiotics Oral + Ent Probiotic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Healthy
Probiotics on Stress-associated Gastrointestinal Function in University Students
The purpose of this research study is to evaluate the effect of a daily supplement of probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, Bifidobacterium longum MM-2) on stress-associated gastrointestinal…
- Trial name
- SAS (NCT03056846)
- Testing
- Probiotic Combination, Bifidobacterium bifidum, Bifidobacterium longum
- Where
- United States
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University of Florida
Gut Microbiota Diversity and Composition, Gut Microbiota Modulation
Effects of Barley and Kefir on Gut Microbiota in Physically Active Adults
The purpose of this randomized controlled clinical trial is to investigate whether a four-week dietary intervention consisting of a daily meal with barley and kefir can influence gut microbiota diversity and composition in…
- Conditions
- Gut Microbiota Diversity and Composition, Gut Microbiota Modulation, Probiotic, Prebiotic
- Trial name
- GUTS (NCT07864779)
- Testing
- Barley, Kefir
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western Norway University of Applied Sciences
Gastroenteritis, Bacterial Infection
The Effect of Probiotics on E. Coli-induced Gastroenteritis
Background: The incidence of gastrointestinal infections is very high. In Western countries at least 30% of the population suffers from at least one food-borne infection per year.
- Conditions
- Gastroenteritis, Bacterial Infection, Diarrhea
- Trial name
- PROTETEC (NCT01709266)
- Testing
- Probiotics
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
Weight Loss
Use of Probiotics to Aid in Weight Loss
The purpose of this study is to evaluate the success of daily supplementation of multiple probiotic bacterial cultures over 12 weeks in increasing the percentage of excess weight loss in the RNYGB (Gastric Bypass) weight loss…
- Trial name
- Probiotics (NCT01445704)
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Gastrointestinal Symptoms
Effects of GlutenShield, a Prebiotic, Probiotic, and Enzyme Supplement, on the Gut Microbiome of Adults With GI Symptoms
This study evaluates the effects of combination probiotic, prebiotic, and enzyme supplementation on the colonic microbiome of individuals with GI symptoms (e.g. diarrhea, constipation, increased gas).
- Trial name
- NCT03403387
- Testing
- GlutenShield
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Prevention of Iron Deficiency
Efficacy of Probiotics on Iron Status During Pregnancy
Determine the effect of probiotics on improving iron status in a population of healthy, pregnant women.
- Trial name
- NCT02912416
- Testing
- Probiotics
- Where
- Sweden
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Probi AB
Aged, Healthy
New E-Service for a Dietary Approach to the Elderly
Ageing of the population is a major event in the world. Gerontological/geriatric literature unanimously indicate that physical exercise and diet are at present the two available fundamental approaches to contrast/prevent most of…
- Trial name
- RISTOMED (NCT01179789)
- Testing
- Optimal Diet, VSL#3®, AISA-5203-L
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy, Stress, Psychological
Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
The aim of this study is to assess whether a 5 week intake of a probiotic (Lpc-37) can modulate stress and anxiety experienced by healthy subjects during and after an acute stressor compared to placebo.
- Trial name
- NCT03494725
- Testing
- Lpc-37
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Daacro
Infant Colic, Atopic Dermatitis
Use of Bifidobacterium Bifidum in Formula-Fed Infants With Colic, With or Without Atopic Dermatitis
The goal of this clinical trial is to evaluate whether daily probiotic supplementation with Bifidobacterium bifidum (Bifipral® drops) can reduce crying time in formula-fed infants aged 5 months or younger diagnosed with infant…
- Trial name
- NCT07754968
- Testing
- Bifidobacterium bifidum BFP19® and BFP29® (Bifipral®)
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Mild to Moderate Levels of Stress
Psychophysiological Effects of Probiotic Supplementation
This is a pilot exploratory study to investigate the effects of a probiotic Bifidobacterium longum NCC3001 intake on physiological and psychophysiological parameters related to stress in healthy individuals with mild to moderate…
- Trial name
- NCT05226520
- Testing
- Experimental probiotic product
- Where
- Switzerland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity, Insulin Resistance
Targeting the Gut Microbiome to Investigate the Pathways of Progression From Obesity to Metabolic Diseases in an At-risk Population.
Studies of the human gut microbiome have suggested that treatment or prevention aimed at the obese microbiome could influence the development of obesity-associated metabolic disturbances.
- Trial name
- NCT01433120
- Testing
- Lactobacillus paracasei ssp paracasei F19, Flax seed fibres
- Where
- Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Oral Microbiome
The Probiotic for Oral Health (PRO Health) Study
The PRO Health Study is a single-center, prospective, double-blind, randomized, placebo-controlled trial of streptococcus-containing supplementation in healthy adults.
- Trial name
- PRO Health (NCT03748017)
- Testing
- Streptococcus-Containing Probiotic Supplement
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
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