Clinical trials: Probiotic Supplement
Diarrhea, Acute Respiratory Infection
Oral Supplement for Pregnant and Lactating Mothers
To assess protection against early life infections through supplementation of mothers during pregnancy to the newborns' growth, morbidity, immune status intra and extra-uterine.
- Trial name
- NCT01073033
- Testing
- milk supplement 1, milk supplement 2
- Where
- Philippines
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
- Trial name
- NCT06794619
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Gut Microbiota
Impact of Probiotics Supplement on the Gut Microbiota in Caesarean-born Infants
The purpose of this study is to evaluate the effect of probiotics on the gut microbiota of infants born by cesarean section.
- Trial name
- NCT05086458
- Testing
- probiotics
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Premature Ovarian Failure (POF)
The Influence of Gut Microbiota on Ovarian Function: A Single-center, Randomized,Double Blind, Parallel-controlled, Exploratory Clinical Trial
In order to study the community profile of the intestinal microbiome in women with ovarian dysfunction, as well as the relationship between the changes in the intestinal microbiota and sex hormones, this study recruited 30 women…
- Trial name
- NCT07308327
- Testing
- Akk Gut Bacteria Supplement
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Songling Zhang
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Gastrointestinal Symptoms, Digestive Health
An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System
This clinical research study is being conducted to evaluate gut and digestive health before and after the use of a dietary supplement system over an eight-week period.
- Conditions
- Gastrointestinal Symptoms, Digestive Health, Gut Health
- Trial name
- NCT07421596
- Testing
- PhytoPower 1 and PhytoPower 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Gastrointestinal Symptoms
Effects of GlutenShield, a Prebiotic, Probiotic, and Enzyme Supplement, on the Gut Microbiome of Adults With GI Symptoms
This study evaluates the effects of combination probiotic, prebiotic, and enzyme supplementation on the colonic microbiome of individuals with GI symptoms (e.g. diarrhea, constipation, increased gas).
- Trial name
- NCT03403387
- Testing
- GlutenShield
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Aged, Healthy
New E-Service for a Dietary Approach to the Elderly
Ageing of the population is a major event in the world. Gerontological/geriatric literature unanimously indicate that physical exercise and diet are at present the two available fundamental approaches to contrast/prevent most of…
- Trial name
- RISTOMED (NCT01179789)
- Testing
- Optimal Diet, VSL#3®, AISA-5203-L
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy, Stress, Psychological
Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
The aim of this study is to assess whether a 5 week intake of a probiotic (Lpc-37) can modulate stress and anxiety experienced by healthy subjects during and after an acute stressor compared to placebo.
- Trial name
- NCT03494725
- Testing
- Lpc-37
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Daacro
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Gastrointestinal Discomfort
Safety and Efficacy of a Probiotic Supplement
Exercise-induced gastrointestinal dysfunction is common amongst endurance athletes and is characterized by gastrointestinal permeability, also known as "leaky gut." Probiotics have been shown to improve gut permeability through…
- Trial name
- NCT05425329
- Testing
- I3.1
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Obesity, Hyperglycemia
The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass
Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium…
- Conditions
- Obesity, Hyperglycemia, Insulin Resistance
- Trial name
- MetSProb (NCT01978691)
- Testing
- Bifidobacterium animalis ssp. lactis 420, Polydextrose
- Where
- 4 sites in Finland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Danisco
Microbiota, Constipation
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study
This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast…
- Conditions
- Microbiota, Constipation, Candida
- Trial name
- NCT05614726
- Testing
- 575mg [30 billion colony forming units] probiotic blend of Bifidobacterium breve, Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Saccharomyces boulardii, and alpha amylase
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Adverse Effects, Healthy
Effect of Probiotic Intake in Healthy Population
The main objective of this project is to evaluate the absence of adverse gastrointestinal effects following the consumption of a daily probiotic capsule during 15 days.
- Trial name
- PROBIO (NCT07165457)
- Testing
- Probiotic group
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Microbial Colonization
Effect of a Multi Strain Probiotic on the Gut Microbiota
Over recent years there has been a lot of research looking at how the bacteria in our gut affect our health. Changes to gut bacteria has been linked to several diseases.
- Trial name
- NCT04554641
- Testing
- Fasted breath samples, Daily Diary, Stool sample
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Functional Gut Clinic
Clostridium Difficile Infection Recurrence
Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
The purpose of this study is to determine whether a single strain capsulated probiotic, when used after standard C. difficile antibiotic therapy, is effective in reducing the risk of infection recurrence mediated by a decrease in…
- Trial name
- NCT05606159
- Testing
- Bacillus velezensis DSM 33864
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novozymes A/S
Probiotics, Acute Exercise
The Effect of Probiotics on Exercise Performance and Recovery
This project will involve administering a multi-strain probiotic supplement to investigate the capacity to improve exercise performance and/or recovery. This will be done by assessing physiological measures (e.g.
- Trial name
- NCT05588674
- Testing
- Probiotic Supplement
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome
Safety and Efficacy of a Probiotic Supplement in IBS-D
This study aims to assess the safety and efficacy of a single probiotic strain on symptom severity in adults with diarrhea-predominant Irritable Bowel Syndrome (IBS-D).
- Trial name
- IBIS (NCT05754177)
- Testing
- Probiotic
- Where
- Slovenia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Iron-deficiency
How Does a Synbiotic Supplement Affect Iron Status During Iron Repletion in Iron Depleted Female Athletes?
Iron deficiency (ID) affects ~30% of female athletes, and its consequences are highly relevant to athletic performance. Poor iron (Fe) uptake remains a major factor in the development of ID.
- Trial name
- NCT03793959
- Testing
- Synbiotic Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marywood University
Obesity, Food Addiction
Probiotic Intervention Study
The current standard of care for obesity is the optimal management of comorbid conditions such as diabetes and hyperlipidemia, and counseling on diet, weight loss, or increased physical activity programs.
- Trial name
- NCT06030362
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles