Clinical trials: Prognostic
Coronary Artery Disease (CAD)
Prognostic Value of High Dose Dobutamine Stress Magnetic Resonance Imaging
High-dose dobutamine/atropine stress cardiac magnetic resonance imaging (DS-MRI) has been incorporated in daily clinical practice for the detection of ischemic heart disease.
- Trial name
- DS-Prognosis (NCT00837005)
- Where
- Germany
- Volunteers
- 2,500 people
- Sponsor
- Heidelberg University
Sepsis, Severe Infection
Mechanisms of Prognostic Regulation andPrecision Phenotype Ldentification in Severe Infections Driven by SpecializedPro-Resolving Mediators
This is a prospective observational study involving adult patients with severe infection who are admitted to the intensive care unit (ICU). Severe infection and sepsis are major causes of death worldwide.
- Conditions
- Sepsis, Severe Infection, Multiple Organ Dysfunction Syndrome, Critical Illness
- Trial name
- MPR-PPI-SPMs (NCT07353970)
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
ABPA, Allergic Bronchopulmonary Aspergillosis
Fungal Status and Prognosis in ABPA
This multicenter bidirectional cohort study aims to investigate the clinical characteristics and prognostic outcomes of patients with allergic bronchopulmonary aspergillosis (ABPA) stratified by fungal microbiological status in…
- Conditions
- ABPA, Allergic Bronchopulmonary Aspergillosis, Allergic Bronchopulmonary Aspergillosis (ABPA), Colonization
- Trial name
- ABPAFUNGAL (NCT07690345)
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Qianfoshan Hospital
Invasive Pulmonary Aspergillosis
PCR for Aspergillus Fumigatus in Blood and Bronchoalveolar Lavage Fluid for Monitoring Cases of Invasive Aspergillosis: What is Its Prognostic Value
Aspergillus fumigatus PCR is currently used in conjunction with serum galactomannan to support the diagnosis of invasive aspergillosis or for monitoring at-risk patients not receiving antifungal prophylaxis.
- Trial name
- ASP (NCT07313527)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Carcinoma, Renal Cell, Pathology
Prognostic Significance of Preoperative Hemoglobin A1c (HbA1c) in Renal Cell Carcinoma
The effect of preoperative glycemic control measured by HbA1c on renal cell carcinoma (RCC) outcome remains controversial. Thus, the investigators aim to examine the association of preoperative glycemic control with oncologic…
- Conditions
- Carcinoma, Renal Cell, Pathology, Treatment Outcome, Hemoglobin A1c Protein, Human
- Trial name
- NCT02417194
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Ultra-low-dose CACS in a Large Population
Radiation exposure to patients from CT for CAC scoring has steadily decreased in recent years. This is mainly achieved through lowering tube currents alongside with the introduction of iterative reconstruction algorithms which…
- Trial name
- ULDCACSLARGE (NCT03637231)
- Testing
- Ultra low-dose CTAC
- Where
- Switzerland
- Volunteers
- 301 people
- Sponsor
- University of Zurich
Acute Chest Pain, Acute Coronary Syndrome
Prognostic Value of Cardiovascular Risk of sST2 and Troponin I-hs in Patients With Acute Chest Pain
The role of the sST2 biomarker has been widely explored in heart failure, so much so that it was included in the AHA guidelines in 2013 and 2017.
- Trial name
- sST2 (NCT05752188)
- Testing
- Multimarker approach in acute coronary syndrome
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sepsis, Shock
Studies of Blood DNA in Patients With Severe Infection DYNAMICS
Severe sepsis (ie. life-threatening infections) is triggered by harmful microorganisms or their toxins in the blood or tissues. These harmful agents damage the lining of blood vessels which can lead to inflammation, blood clot…
- Conditions
- Sepsis, Shock, Trauma
- Trial name
- DYNAMICS (NCT01355042)
- Where
- 6 sites in Canada
- Volunteers
- 792 people
- Sponsor
- Alison Fox-Robichaud
Acute Coronary Syndromes, Geriatric Patients
Prognostic Importance of Physical Activity in Geriatric Patients With Acute Coronary Syndrome
This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS).
- Conditions
- Acute Coronary Syndromes, Geriatric Patients, Physical Activity Levels
- Trial name
- NCT07203924
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Balikesir University
Liver Cirrhosis
Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF)
Patients with acute on chronic liver failure have a risk of developing multiorgan failure and a high mortality. The current scoring systems defining the outcome of patients with acute decompensation of cirrhosis fail to identify…
- Trial name
- DASIMAR (NCT01071746)
- Where
- United Kingdom
- Volunteers
- 700 people
- Sponsor
- University College London Hospitals
Patients
Prognostic Biomarkers of Pancreatic Cancer Based on Proteomics Techniques
In this study, we will use high-throughput proteomics techniques to search for biomarkers of post-operative prognosis of pancreatic cancer in samples of patients who have been diagnosed with pancreatic cancer through…
- Trial name
- NCT05088161
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Non Small Cell Lung Carcinoma
Prognostic Role of Primary Non Small Cell Lung Carcinoma Standardized F18-FDG Uptake Values (SUV and TLG) Measured With F18-fluorodeoxyglucose Positron Emission Tomography (F18-FDG-PET): a Non Interventional Study.
The primary aim of this non interventional study is to assess the independent prognostic role on overall survival of primary tumour 18F-FDG uptake value (SUVmax) measured on 18fluorodeoxyglucose positron emission tomography…
- Trial name
- NCT00759382
- Where
- 6 sites in Belgium
- Volunteers
- 340 people
- Sponsor
- European Lung Cancer Working Party
Sickle Cell Disease
Dense Red Blood Cells in Sickle Cell Children
Quantitative and prognostic evaluation of dense red blood cells in sickle cell children: preliminary single center study from the Creteil pediatric cohort.
- Trial name
- DREPADENSE (NCT02887118)
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Autoimmune Hemolytic Anemia, Immune Thrombocytopenia
Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia
The goal of this observational study is to characterize the diagnostic and therapeutic management of autoimmune cytopenias including autoimmune hemolytic anemia, immune thrombocytopenia, and chronic idiopathic/autoimmune…
- Conditions
- Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, Chronic Idiopathic Neutropenia, Autoimmune Neutropenia
- Trial name
- AIHA ITP CIN (NCT05931718)
- Testing
- cytokine essays, NGS, Fecal microbiome
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lymphoma
S9704-S0014-S0313A Studying Genes in Samples From Patients With Limited or Advanced Diffuse Large B-Cell Lymphoma
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors find better ways to treat cancer.
- Trial name
- NCT01563861
- Testing
- RNA analysis, gene expression analysis, immunohistochemistry staining method
- Volunteers
- 397 people
- Sponsor
- SWOG Cancer Research Network
Endophthalmitis
Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 Months
OZURDEX endophthalmitis is a rare and potentially very serious pathology. Different treatments can be carried out early and change the functional prognosis of the patient.
- Trial name
- NCT06268561
- Testing
- Visual acuity analysis, Intraocular pressure analysis, Analysis of optical coherence tomography (OCT) images
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infertility
The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization
This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.
- Trial name
- NCT06319573
- Testing
- Counseling Supported by Univfy® Report, Standard Counseling
- Where
- 2 sites in Spain
- Volunteers
- 366 people
- Sponsor
- Ginefiv
Pancreatic Tumor
Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors
Pancreatic cancer is among the most serious human neoplasia and the most difficult to treat. Most patients present at diagnosis a non resectable, locally advanced or metastatic disease, with a median survival of 12 month.
- Trial name
- PACAomics (NCT01692873)
- Testing
- suspected pancreatic tumor
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Institut Paoli-Calmettes
Severe Sepsis, Septic Shock
Prognostic Evaluation Of Severe Sepsis And Septic Shock. Procalcitonin Versus Delta Sofa
The purpose of this study is to compare the tendency of plasma concentration and clearance of procalcitonin in the first 24 and 48 hours of management of patients with severe sepsis and septic shock with another marker of early…
- Trial name
- NCT01841190
- Where
- 2 sites in Brazil
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Domingos
Bariatric Surgery Candidate
Preoperative Dry Lean Body Mass as a Prognostic Factor for Excess Weight Loss After Bariatric Surgery.
Bariatric surgery is currently the only method that has proven long-term effectiveness in obesity. Although the benefit of physical activity on weight loss has been demonstrated, no correlation has ever been reported between…
- Trial name
- MMS-CB (NCT03558360)
- Testing
- Impedance measurement
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Departemental Vendee