Clinical trials: Prolapse
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Organ Prolapse
Anchor for Robotic Sacrocolpopexy
1. PRIMARY OBJECTIVE: To assess the effect of absorbable anchor compared to suturing for mesh attachment to vagina in robotic assisted sacrocolpopexy on the length of surgery for this portion of the procedure. 2.
- Trial name
- ARiSe (NCT03378622)
- Testing
- Anchor, Suture
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Overactive Bladder, Pelvic Organ Prolapse
The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair
Pelvic organ prolapse (POP) is a common condition in women. Approximately 20% of women undergo surgical correction for POP in their lifetime.
- Trial name
- NCT02502838
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Colon Cleansing
Will Cleaning the Bowel With an Enema Before Vaginal Prolapse Surgery Prevent Complications?
Traditionally, many gynecologic surgeons have asked patients to perform a cleansing enema the night before a vaginal surgery done to repair pelvic organ prolapse (dropped bladder, dropped uterus).
- Trial name
- NCT00981539
- Testing
- enema
- Where
- 2 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Illinois Urogynecology, Ltd.
Pelvic Organ Prolapse
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse
Data on smoking and POP are conflicting. In a study done by Alnaif et al, smoking was found to be associated with severe POP. The authors' proposed explanation was that smoking impairs tissue and wound healing.
- Trial name
- NCT01548105
- Testing
- Blood draw for the study participants
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Pelvic Organ Prolapse
Predictors of Post Operative Morbidity in Older Women With Pelvic Organ Prolapse
The Investigators hypothesize that functional status scores in elderly women undergoing surgery for pelvic organ prolapse will be lower at 6 weeks post-operatively but will have returned to baseline at 12 weeks post-operatively.
- Trial name
- NCT01967446
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Rectocele, Pelvic Organ Prolapse
An Intervention to Improve Prolapse Using Femmeze® (v1)
The main purpose of the feasibility study is to identify the patient experience of Femmeze® which is a device aimed at improving posterior vaginal compartment prolapse (rectocele) for women with obstructive defaecation.
- Trial name
- Femmeze® (NCT02280382)
- Testing
- Femmeze®
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Pelvic Organ Prolapse
Outcomes and Patient Satisfaction After Colpocleisis for Pelvic Organ Prolapse
The purpose of this study is to evaluate the long-term success rate of the colpocleisis procedure and its effect on quality of life in women who have this surgery.
- Trial name
- NCT00714155
- Testing
- Questionnaires, Physical Examination
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cystocele
Lower Urinary Tract Symptoms Screening Questionnaire
The purpose of this study is to determine the validity of a screening tool which has been designed to detect the presence or absence of lower urinary tract symptoms in the general female population.
- Trial name
- LUTS-2 (NCT01616810)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Prolapse
Evaluation of TP US in Women With Prolapse
Many women suffers from uterine and vaginal prolapse Usually they suffer from these symotoms in menopause
- Trial name
- NCT03820089
- Testing
- Ultrasonography TP
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Post-Operative Pain, Pelvic Organ Prolapse
Post-Operative Pain Control Using Direct Continuous Bupivacaine Infusion After Pelvic Organ Prolapse Repair
This prospective randomized controlled study will determine the efficacy of continuous local anesthesia at decreasing pain scores compared to patient controlled analgesia for pelvic organ prolapse procedures including posterior…
- Trial name
- NCT00695240
- Testing
- Continuous bupivacaine analgesia infusion (ON-Q PainBuster Post-Op Pain Relief System)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Kansas City, Missouri
Urinary Retention Postoperative
Effect of Phenazopyridine on Prolapse Surgery Voiding Trials
To determine if phenazopyridine reduces the rate of postoperative urinary retention after pelvic organ prolapse surgery.
- Trial name
- EPOV (NCT03065075)
- Testing
- Phenazopyridine
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pelvic Organ Prolapse, Stress Urinary Incontinence
Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Surgery
Pelvic organ prolapse occurs with descent of one or more pelvic structures: the uterus and/or cervix, bowel, bladder, or rectum.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Satisfaction
- Trial name
- NCT02111642
- Testing
- Online risk calculator
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Cleft Palate
Pilot Study Evaluating Characteristic Closure Patterns of the Normal Velopharyngeal Portal
This prospective research study seeks to determine how the normal velopharyngeal mechanism compares, both anatomically and physiologically, with previous data obtained on subjects with submucous cleft palate (SMCP) in…
- Trial name
- NCT00773994
- Testing
- Normal Velopharyngeal Mechansim
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Congenital Ptosis
Research on Precision Diagnosis and Treatment Decision of Common Eye Diseases Based on Artificial Intelligence
The goal of this observational study is to investigate the clinical features of congenital ptosis in children by analyzing eyelid movement captured through smartphone videos.
- Trial name
- NCT07078552
- Testing
- ptosis
- Where
- China
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Urinary Incontinence, Pelvic Organ Prolapse
Promoting Effective Recovery From Labor Urinary Incontinence (PERL)
The purpose of this study is to determine whether pushing during labor that is controlled by the woman results in less birth-related injury and less postpartum urinary incontinence (UI).
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
- Trial name
- PERL (NCT00506116)
- Testing
- Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Myasthenia Gravis, Ocular Myasthenia Gravis
Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis
This study is aimed at assessing the efficacy of Apraclonidine eye drops in the treatment of ptosis secondary to myasthenia gravis.
- Trial name
- NCT05045248
- Testing
- Apraclonidine Hcl 0.5% Oph Soln
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Body Image, Urinary Incontinence
Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function
The first objective to determinate the prevalence of pelvic floor dysfunction in pregnant women and in the first year postpartum.
- Conditions
- Body Image, Urinary Incontinence, Anal Incontinence, Anorectal Disorder
- Trial name
- PFD-BI (NCT03591393)
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven