Clinical trials: Prolapse
Pelvic Organ Prolapse
Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse
This study is being done to evaluate the safety and feasibility of using flat polypropylene Restorelle® mesh, an ultra-lightweight mesh, for transvaginal use in surgically correcting certain specific cases of pelvic organ…
- Trial name
- NCT06225375
- Testing
- Restorelle® Flat Mesh
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Orbital Fat Prolapse
Safety and Efficacy Evaluation of UltheraTM in Treatment of Baggy Eyelid
Study title Safety and Efficacy Evaluation of UltheraTM in Treatment of Baggy Eyelid Study design single arm and Investigator Initiative pilot study
- Trial name
- NCT01693055
- Testing
- UltheraTM 100 shots
- Where
- South Korea
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pelvic Organ Prolapse, Sexual Dysfunction
The Association of Pelvic Organ Prolapse Severity and Urinary Symptoms and Sexual Function
Women with pelvic organ prolapse often accompany with urinary symptoms or sexual dysfunction, and analyzing the association will be helpful to identify the indication of proper management.
- Conditions
- Pelvic Organ Prolapse, Sexual Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- NCT01776580
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stress Urinary Incontinence, Genital Prolapse
Dynamic MRI of the Behaviour of Female Pelvic Floor
The purpose of this study was to test the suitability of dynamic magnetic resonance imaging for the pelvic floor floor, bladder neck and urethra in healthy volunteers, in stress incontinent patient and in women with genital…
- Trial name
- NCT00747370
- Testing
- movement of midurethra, bladder neck, cervix and rectum
- Where
- Finland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Pelvic Organ Prolapse
Tranexamic Acid in Vaginal Reconstructive Surgery
Tranexamic acid (TXA) has been demonstrated to reduce blood loss in trauma, orthopedic, cardiac, and plastic surgeries in numerous well-designed and adequately powered studies.
- Trial name
- TEXAS (NCT06419075)
- Testing
- Tranexamic acid, Vasopressin, NaCl 0.9%
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Pelvic Organ Prolapse, Surgery
Comparison of Two Apical Repair Methods in Women Undergoing Repairs for Prolapse
To date no study has determined prospectively which technique is superior to prevent recurrent Pelvic Organ Prolapse (POP) after vaginal hysterectomy- a major unmet clinical need.
- Conditions
- Pelvic Organ Prolapse, Surgery, Quality of Life, Complication
- Trial name
- NCT03113513
- Testing
- fixation of the vaginal apex
- Where
- Austria
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Stress Urinary Incontinence
Concurrent Surgery for Prolapse and Stress Urinary Incontinence to Reduce Further Surgery for Incontinence
Urinary incontinence is a common and distressing medical condition which affects 26% of women in developing countries.Globally upto 54% women suffer from pelvic organ prolapse and stress urinary incontinence concomitantly.Women…
- Trial name
- NCT06521450
- Testing
- anti incontinence surgery
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Pelvic Organ Prolapse
Predictors of Post Operative Morbidity in Older Women With Pelvic Organ Prolapse
The Investigators hypothesize that functional status scores in elderly women undergoing surgery for pelvic organ prolapse will be lower at 6 weeks post-operatively but will have returned to baseline at 12 weeks post-operatively.
- Trial name
- NCT01967446
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pelvic Organ Prolapse
The Purpose of This Study is to Look at Pelvic Support Problems, Also Commonly Known as Pelvic Organ Prolapse
FemmeJock is a pelvic floor support system developed by pelvic floor physiotherapists for patients with pelvic organ prolapse in order to ameliorate symptoms of pelvic floor pressure and discomfort.
- Trial name
- NCT00964197
- Testing
- FemmeJock
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pelvic Organ Prolapse
Pectopexy Surgery Without Mesh
it is aimed to examine the effect of laparoscopic pectopexy surgery without mesh on Pelvic Organ Prolapse Measurement (POP-Q) and quality of life of the patient.
- Trial name
- NCT05715489
- Testing
- Comparison of pre and postoperative POP-Q values of the patients, Comparison of pre and postoperative PISQ-12 scores of the patients
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ptosis, Eyelid
Effect of Eyelid Patching After Ptosis Surgery
The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery.
- Trial name
- NCT05770973
- Testing
- Compression dressing (build by Kompressen, gauze swabs, Nobamed Paul Danz AG, Wetter, Germany and NOBALUMENAL® - steril, eye pad, Nobamed Paul Danz AG, Wetter, Germany
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augenklinik LMU
Vaginal Vault Prolapse
Study of Cytrix Use in Pelvic Floor Prolapse Treatment
To evaluate safety and effectiveness of using the fetal bovine dermis (Cytrix) in the treatment of pelvic organ prolapse.
- Trial name
- NCT01244165
- Testing
- Cytrix, Other treatments for pelvic organ prolapse
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Anterior Vaginal Wall Prolapse, Cystocele
Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
The purpose of this study is to evaluate the success rate of cystocele repair using polypropylene mesh or porcine dermis compared to that of anterior colporrhaphy in a prospective randomized fashion.
- Conditions
- Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- OARS (NCT01393171)
- Testing
- Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
the Indications and Clinical Efficacy of Pelvic Organ Prolapse Surgery
One thousand patients with stage>2 POP are recruited. The patients are all received surgeries,such as transvaginal synthetic mesh surgery, the sacral fixation, tissue repair surgery and colpocleisis.
- Trial name
- NCT02599311
- Testing
- transvaginal synthetic mesh, Tolterodine
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Pelvic Organ Prolapse
Sacro-Spinous Ligaments Anterior Apical Anchoring
Anterior-apical compartment mesh implants for pelvic floor reconstruction are anchored here to the Sacro-Spinous ligaments and evaluated being a feasible and effective method.
- Trial name
- NCT01842464
- Testing
- Anterior Sacro-Spinous
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Pelvic Floor Dysfunction, Postpartum Care
Comparison of Outpatient Rehabilitation Versus Self-training for the Treatment and Prevention of Postpartum Pelvic Floor Dysfunction
The main goal of this study to compare self-training postpartum and training with a specialist support (physiotherapist and physical medicine and rehabilitation doctor) effect on pelvic floor dysfunction prevention and treatment…
- Conditions
- Pelvic Floor Dysfunction, Postpartum Care, Postpartum Comfort, Female Urinary Incontinence and Pelvic Organ Prolapse
- Trial name
- DDDPREV (NCT07426770)
- Testing
- Rehabilitation postpartum, Self-training
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vilnius University