Clinical trials: Prolapsed Intervertebral Disc
Degenerative Disc Disease, Degenerative Spondylolisthesis
The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy
The five-repetition sit-to-stand test (5R-STS) has been used in many medical disciplines, but has never been correlated with or validated in regard to degenerative spinal diseases.
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Herniated Disc, Stenosis, Spinal
- Trial name
- 5R-STS (NCT03303300)
- Where
- Netherlands
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Marc Schröder
Lumbar Disc Herniation
Intradiscal Ozone/Oxygen Injection for Treatment of Contained Lumbar Disc Herniation
This study is retrospectively designed and aims to evaluate and summarize safety and performance data in eligible participants who have undergone Intradiscal ozone-oxygen injection for treatment of lumbar disc herniation with the…
- Trial name
- NCT07910422
- Testing
- Intradiscal ozone-oxygene injection
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Beam Research, Inc.
Cervical Disc Disease, Cervical Stenosis
Is There a Risk of Perioperative Stroke Due to the Retraction Used During Anterior Cervical Discectomy?
In anterior cervical disc surgery, head and neck extansion position and, surgical retraction used while reaching the anterior surface of the cervical vertebra can be affect the carotid blood flow and constituting a risk for…
- Conditions
- Cervical Disc Disease, Cervical Stenosis, Cervical Disc Herniation
- Trial name
- NCT05717010
- Testing
- Near infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Samsun University
Cervical Disc Herniation
Impact of Cervical Parameters to Interlaminar Epidural Steroid Injection Treatment Outcomes in Patients With Cervical Disc Herniation
This study is aim to disclose the effect of cervical parameters, whether they change the outcomes of epidural steroid injection treatment in patients with cervical disc herniation.
- Trial name
- NCT05374850
- Testing
- Cervical Interlaminar Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Low Back Pain, Disk Prolapse
Effects of Physical Therapy on Improving Disc Height, Postural Stability, Pain and Function in Persons With Discogenic Low Back Pain
Lumbar degenerative disc disease and discogenic low back pain is comparatively common and disabling musculoskeletal condition, however there is no conclusive evidence regarding the positive effects of conservative physical…
- Trial name
- NCT05326594
- Testing
- Mckenzie Extension Protocol, Lumbar SNAGs, Inferential therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Disk Herniated Lumbar, Coordination Lack
The Effect of Abdominal Hallowing on Coactivation of Lower Extremity Muscles in Patients With Lumbal Disc Herniation
Intervertebral disc degenerations are the most important cause of chronic low back pain resulting in job loss and associated socio-economic problems in developed and developing industrial countries 1.
- Conditions
- Disk Herniated Lumbar, Coordination Lack, Muscle Weakness
- Trial name
- NCT05233254
- Testing
- Abdominal Hollowing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Hacettepe University
Degenerative Disc Disease
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss.
- Trial name
- VAST (NCT03709901)
- Testing
- Active Allograft
- Where
- 13 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Lumbar Disc Herniation
Tramadol vs.Tramadol With Paracetamol
This study focused on to determine postoperative analgesic efficacy of tramadol compared to tramadol with addition of paracetamol after a lumbar disc surgery.
- Trial name
- NCT03482492
- Testing
- Tramadol, Paracetamol
- Volunteers
- 60 people
- Sponsor
- Yeditepe University Hospital
Sciatica, Intervertebral Disc Displacement
Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation
This trial will evaluate the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of…
- Trial name
- NCT02384928
- Testing
- Shinbaro pharmacopuncture, Acupuncture, Conventional medicine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Jaseng Medical Foundation
Cervical Disc Herniation, Cervical Radicular Pain
Does the Presence of Cervical Facet Tropism Affect the Response to Interlaminar Epidural Steroid Injections?
Facet joints are synovial joints located on the dorsolateral side of the vertebral column. Normally, both facet joints are symmetrical.
- Conditions
- Cervical Disc Herniation, Cervical Radicular Pain, Facet Tropism
- Trial name
- NCT05638074
- Testing
- Interlaminar Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Janbubi Jandaulyet
Radiculopathy, Cervical
The Norwegian Cervical Arthroplasty Trial
The study will compare cervical arthroplasty with cervical discectomy and fusion, in the treatment of cervical radiculopathy. The 0-hypothesis is that there is no difference between the two methods, when comparing primary and…
- Trial name
- NORCAT (NCT00735176)
- Testing
- Cervical arthroplasty, Anterior cervical discectomy and fusion (ACDF)
- Where
- Norway
- Volunteers
- 136 people
- Sponsor
- Norwegian University of Science and Technology
Disk Hernisi, Visseral Manuel Terapi
The Effect of Visceral Osteopathic Manual Therapy in Lumbar Disc Herniation
This study aims to investigate the impact of adding visceral osteopathic manual therapy techniques to conservative physical therapy on the lives of individuals with lumbar disc herniation.
- Trial name
- NCT07465068
- Testing
- osteopathic manual therapy, FTR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Rumeli University
Radiculopathy, Spinal Stenosis
Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other.
Patients are being asked to participate in a research study because the patients are being treated for low back pain and the patients have decided to have an epidural steroid injection.
- Conditions
- Radiculopathy, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT02196883
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Nursing Care, Spine Surgery
Dependence, Frailty, and Kinesiophobia on Early Postoperative Mobilization and Self-Care Ability in Patients Undergoing Lumbar Disc Herniation Surgery
Lumbar disc herniation is a common condition that may impair physical functioning and reduce independence in activities of daily living.
- Conditions
- Nursing Care, Spine Surgery, Perioperative Care
- Trial name
- NCT07762183
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Aydin Adnan Menderes University
Lumbar Disc Herniation, Lumbosacral Radiculopathy
Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain
This study will compare three fluoroscopy-guided epidural steroid injection approaches for adults with unilateral lumbosacral radicular pain caused by lumbar disc herniation.
- Trial name
- NCT07813988
- Testing
- High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Benha University
Low Back Pain, Herniated Lumbar Disk
RELATIONSHIP OF LUMBOPELVIC MUSCULATURE WITH FUNCTIONAL TESTS IN NON-PROFESSIONAL ATHLETES WITH LUMBAR DISC HERNIATION
This is a control-case study. It has been designed to determine if there is a relationship between the cross sectional (thickness), through RUSI ultrasound, of the abdominal muscles, lumbar and hip muscles with the results of the…
- Conditions
- Low Back Pain, Herniated Lumbar Disk, Sciatica
- Trial name
- NCT03880370
- Testing
- Questionnaires / scales, Ultrasound imaging, FLEXIBILITY
- Volunteers
- 60 people
- Sponsor
- Universidad Complutense de Madrid
Lumbar Disc Herniation
Plane Block vs Intravenous Patient Controlled Analgesia
Acute postoperative pain begins with surgical trauma and decreases with tissue healing. Untreatable postoperative pain is one of the most important problems due to the increase in respiratory, cardiac and thromboembolic…
- Trial name
- NCT04457986
- Testing
- Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Diskapi Teaching and Research Hospital
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Motor Imagery, Neck Pain
Motor Imagery Ability and Cervical Discogenic Pain
Background: The purpose of the study was to examine the motor imagery ability and its association with pain, functional status, neck awareness and depression levels in individuals with cervical discogenic pain (CDP).
- Conditions
- Motor Imagery, Neck Pain, Disc Herniation, Functional Status
- Trial name
- NCT06502236
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University