Clinical trials: Prolonged Grief Disorder
Prolonged Grief Disorder, Complicated Grief
Transcranial Magnetic Stimulation to Treat Prolonged Grief Disorder
Grief is a normal response after the death of a loved one. With time, the grief response decreases and people learn to cope with their loss. However, for some, the response becomes more intense and distressing.
- Trial name
- NCT06953596
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Bruyère Health Research Institute.
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
Bereavement, Prolonged Grief Disorder
Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age
While most bereaved individuals cope adaptively with the loss of a loved one, a significant minority experiences more severe and complicated grief reactions.
- Conditions
- Bereavement, Prolonged Grief Disorder, Depression, Anxiety
- Trial name
- NCT04694807
- Testing
- Group-based Cognitive Behavioural Therapy for Complicated Grief Reactions, Individually delivered Cognitive Behavioural Therapy for Complicated Grief Reactions
- Where
- Denmark
- Volunteers
- 113 people
- Sponsor
- University of Aarhus
Prolonged Grief Disorder (PGD)
Understanding and Responding to Grief-Related Needs: A Differentiated Community Approach
The GriefDiff study is a randomized controlled trial evaluating a differentiated, community-based model of grief support for older adults.
- Trial name
- GriefDiff (NCT07433101)
- Testing
- IGLiteracy, Arm 2 - Individual Self-Help Program (ISelfHP), Arm 3 - Moderated Self-Help Groups (MSHGroups)
- Where
- Portugal
- Volunteers
- 246 people
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Naltrexone HCl 50 MG Oral Tablet, Placebo
Naltrexone for Prolonged Grief Disorder
This is a study to see how effective oral naltrexone is as treatment for prolonged grief disorder (PGD). Participants will take their assigned medication for 8 weeks, with monthly visits to assess symptom severity, social…
- Trial name
- NPGD (NCT06140420)
- Testing
- Naltrexone Oral Product
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Posttraumatic Stress Disorder, Depression
A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
In the framework of the epidemiological study, local psychologists are trained in Butare in carrying out diagnostic interviews with orphans and widows who experienced the Rwandan genocide.
- Conditions
- Posttraumatic Stress Disorder, Depression, Prolonged Grief Disorder
- Trial name
- NCT00553956
- Testing
- Narrative Exposure Therapy/Interpersonal Psychotherapy
- Where
- Rwanda
- Volunteers
- 150 people
- Sponsor
- University of Konstanz
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Grief, Mental Health
Effectiveness of an Internet-Based Self-Management Program in Treating Prolonged Grief Disorder
This study will evaluate the effectiveness of an Internet-based self-help program in treating people who are at risk for developing prolonged grief disorder following a recent loss.
- Trial name
- NCT00598884
- Testing
- Internet-Based Self-Management for Prolonged Grief Symptoms
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Boston University
Physicians' Knowledge and Diagnostic Practices for PGD in Older Adults, Effect of Brief Training on PGD Diagnosis
Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and Practice
Background: Prolonged Grief Disorder (PGD) is a psychiatric diagnosis with significant implications for individuals and society.
- Trial name
- PGD (NCT07487233)
- Testing
- PGD Informational Video, Bereavement Educational Video
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Ruppin Acdemic Center
Grief, Grief Disorder, Prolonged
Families Left Behind
The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief.
- Conditions
- Grief, Grief Disorder, Prolonged, Overdose Accidental, Substance Use Disorders
- Trial name
- NCT06854757
- Testing
- RIVER, Enhanced care as usual
- Where
- 4 sites in United States
- Volunteers
- 340 people
- Sponsor
- RAND
Prolonged Grief Disorder, Bereavement
Oxytocin and Approach-avoid in Grief
This is a completed project which was initiated prior to January 18,2017 Background: Theoretical models of complicated grief (CG) suggest that maladaptive approach (e.g., perseverative proximity-seeking of the deceased) or…
- Trial name
- NCT04505904
- Testing
- Syntocinon
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Arizona
Prolonged Grief Disorder (PGD)
F-PGT - Prolonged Grief Treatment for Families Affected by Suicide
This pilot open trial is being done to better understand the needs of families who have lost a parent to suicide at least a year ago and who have children ages 8-14 and to develop and test Family-Prolonged Grief Treatment…
- Trial name
- F-PGT (NCT07318090)
- Testing
- F-PGT
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Complicated Grief, Prolonged Grief Disorder
Pilot Study of Behavioral Activation for Prolonged Grief
The Institute of Medicine identifies Prolonged Grief (PG) as a critical under-addressed public health problem for which are no empirically supported treatments.
- Conditions
- Complicated Grief, Prolonged Grief Disorder, Major Depressive Disorder, Posttraumatic Stress Disorder
- Trial name
- NCT01556048
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Anthony Papa
Grief Disorder, Prolonged
A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department
In France, a study has reported that about 0.2% of patients visiting the ED died in the ED. A large survey of 145 EDs in 3 French speaking countries has reported that a median of 2 patients dies each week in each ED and its…
- Trial name
- MYRIADE (NCT06733974)
- Testing
- Multi-faceted Intervention
- Where
- France
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prolonged Grief Disorder
Web Based Patient Tutorial on Prolonged Grief
The goal of this clinical trial is to learn about usefulness of the online patient grief tutorial in bereaved adults with Prolonged Grief Disorder who are receiving psychotherapy treatment for it.
- Trial name
- STTR2 (NCT05575817)
- Testing
- Web Based Patient Tutorial on Prolonged Grief Disorder Therapy
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Columbia University
Grief
Adolescent Suicide Loss Survivors Grief Intervention Group
This study will provide evidence-based recommendations for designing interventions tailored to adolescents dealing with suicide loss.
- Trial name
- NCT07151092
- Testing
- Adolescent Grief Group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Post-traumatic Stress Disorder (PTSD), Grief (Traumatic Grief and Existential Grief)
Effects of the Integrated Grief Therapy on Psychological Resilience, Post-Traumatic Growth, Traumatic Stress, and Grief Processes in Earthquake Survivors
This study evaluates the effectiveness of an Integrated Grief Therapy (IGT) group program for adults affected by the February 6, 2023 earthquake in Türkiye.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Grief (Traumatic Grief and Existential Grief), Bereavement
- Trial name
- NCT07641270
- Testing
- Integrated Grief Therapy (IGT)
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Sakarya University
Grief
An Internet-based Self Applied Treatment Program for Prolonged Grief Disorder (PGD)
The purpose os this study is examine the effect and feasibility (usability and satisfaction) of an iCBT (GROw program) for adults with PGD
- Trial name
- PGD (NCT04376385)
- Testing
- GROw: An Internet based Self Applied Treatment Program for Prolonged Grief Disorder (PGD)
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Universitat Jaume I
Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief)
P-CRP for Recent-Onset Severe Trauma
The purpose of this retrospective study was to evaluate the effectiveness of a new psychotherapy technique called Psychological Cognitive Reprocessing Procedure (P-CRP) in treating trauma symptoms.
- Conditions
- Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief), Stress Disorder - Post-traumatic (Acute)
- Trial name
- P-CRP (NCT07360990)
- Testing
- Psychological-cognitive reprocessing procedure (P-CRP)., Expressive Narrative and Symbolic Drawing (ENSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Zahide Betül Baydar