Clinical trials: Prolotherapy
Myofascial Pain Syndrome
Evaluation of Pain Regression in Patients With Myofascial Facial Pain Using Dextrose, Local Anaesthesia and Saline.
The aim of this study is to compare the treatment effects of dextrose prolotherapy, saline, and mepivacaine for deactivating myofascial trigger points within the jaw muscles.
- Trial name
- NCT03161210
- Testing
- Dextrose Prolotherapy, Local Anaesthesia, Saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rehabilitation, Pain, Shoulder
Precision Medicine for Nociception, Sngception and Proprioception.
Precision medicine is defined as "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person" by the Precision Medicine…
- Conditions
- Rehabilitation, Pain, Shoulder, Pain, Chronic, Idiopathic Scoliosis
- Trial name
- NCT06161038
- Testing
- LASER, Ultrasound, Prolotherapy
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Chronic Low Back Pain, Lumbar Facet Joint Osteoarthritis
Ultrasound-Guided Lumbar Facet Joint Injections for Facet-Related Pain: A Randomized Comparison of Saline, Steroid, and 5% Dextrose
This study aims to evaluate the effectiveness of prolotherapy using 5% dextrose compared to steroid and saline injections in patients with lumbar facet joint-related low back pain.
- Trial name
- NCT07528794
- Testing
- Dextrose Injection, Steroid Injection, Saline Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Osteoarthritis
Joint Injections for Osteoarthritic Knee Pain
The purpose of this study is to determine whether prolotherapy (PrT), a therapy based on injection of a sugar solution in and around the knee, can decrease pain and disability from knee osteoarthritis (OA).
- Trial name
- NCT00085722
- Testing
- Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of Wisconsin, Madison
Knee Osteoarthritis
Cost Effectiveness of Prolotherapy Injections Prior to Total Knee Arthroplasty
This study compared the cost effectiveness of two-stage algorithm (prolotherapy injections (PrT) combined with rehabilitation protocol (RP) prior to total knee arthroplasty (TKA)) and one-stage algorithm (TKA) in the management…
- Trial name
- NCT03758183
- Testing
- total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Tokat State Hospital
Myofascial Pain Syndrome of Neck
Comparison of the Efficacy of Prolotherapy Injection Therapy & Local Anesthetic Injection Therapy.
Myofascial pain syndrome is a disease characterized by pain over the trigger point in a taut muscle band. After the correct diagnosis is made, many treatment methods can be applied.
- Trial name
- NCT05239091
- Testing
- Dextrose solution, Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Knee Osteoarthritis
Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by metabolic, biochemical, and structural changes in the articular cartilage and the…
- Trial name
- NCT04006314
- Testing
- Autologous platelet rich plasma and dextrose solution.
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Sacro Iliac Joint Pain, Low Back Pain
Analgesic Effect of Sacral Submultifidus Block as an Adjunct to Sacroiliac Joint Injection
The aim of this study is to assess whether the addition of sacral submultifidus block to standard image-guided SIJ injection provides superior analgesia and functional improvement compared with SIJ injection alone in patients…
- Conditions
- Sacro Iliac Joint Pain, Low Back Pain, Sacroiliatis
- Trial name
- NCT07814729
- Testing
- SIJ Injection Alone, receive SIJ Injection & Sacral Submultifidus Block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Fayoum University Hospital
Partial-Thickness Rotator Cuff Tear
Injection Therapies for Partial Rotator Cuff Tears
This completed study compared four injection treatments in patients with painful partial tears of the rotator cuff, the tendons that help move and stabilize the shoulder.
- Trial name
- NCT07871695
- Testing
- Autologous Platelet-Rich Plasma (PRP), Dextrose 15%, Betamethasone Sodium Phosphate and Betamethasone Acetate
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01706172
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 Sterile water /0.2% lidocaine
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chisel Peak Medical Clinic
Temporomandibular Joint Disorders
Effects of Platelet-rich Plasma Prolotherapy of Temporomandibular Joint Subluxation
The aim of this study is to clinically assess the efficacy of PRP prolotherapy for treatment of TMJ subluxation
- Trial name
- NCT03655275
- Testing
- PRP prolotherapy, Saline prolotherapy
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Abdelrahman Soliman Alateyh
Knee Osteoarthritis
Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis
The purpose of this research is to learn more about treating Symptomatic Knee Osteoarthritis (OA) with an ultrasound-guided hypertonic dextrose injection.
- Trial name
- NCT05160532
- Testing
- Dextrose prolotherapy (DPT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Temporomandibular Joint Disorders, Temporomandibular Disorder
Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction
Purpose of the study is to compare clinically, radiographically and biochemically the effect of intra- articular injection of hypertonic dextrose with a stabilization appliance and the intra- articular injection of 2 ml of liquid…
- Trial name
- NCT04557878
- Testing
- Hypertonic Dextrose Solution, Liquid Phase Concentrated Growth Factor (LPCGFs)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Nourhan M.Aly
Lateral Epicondylitis
Comparison of the Efficacy of Dextrose Prolotherapy and Mesotherapy in Lateral Epicondylitis
A total of 84 patients with lateral epicondylitis were included in the study. The patients were randomly assigned to 3 treatment groups: mesotherapy (n = 28), prolotherapy (n = 28), and control (n = 28).
- Trial name
- NCT06538194
- Testing
- Mesotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Planter Fasciitis
Comparison of Platelet-Rich Plasma and Prolotherapy for Plantar Fasciitis
This randomized controlled trial evaluates the comparative effectiveness of platelet-rich plasma (PRP) therapy and prolotherapy in patients with plantar fasciitis.
- Trial name
- NCT07480967
- Testing
- platelet-rich plasma injection, Prolotherapy with 25% Dextrose
- Where
- Bangladesh
- Volunteers
- 68 people
- Sponsor
- Bangladesh Medical University
Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy
Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears
This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears.
- Conditions
- Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy, Shoulder Pain Chronic, Supraspinatus Tendon Tear
- Trial name
- NCT07688902
- Testing
- Intralesional 5% Dextrose Injection, Perilesional 5% Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Cancer Females
Dextrose Hydrodissection for Post-Breast Cancer Chest Wall and Axillary Tightness.
The goal of this clinical trial (prospective case series) is to evaluate the feasibility, safety, and preliminary clinical outcomes of ultrasound-guided dextrose prolotherapy in female breast cancer survivors with persistent…
- Trial name
- NCT07378319
- Testing
- ultrasound guided dextrose prolotherapy
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Taichung Veterans General Hospital
Low Back Pain
Comparison of Prolotherapy and Rehabilitation Treatments in Low Back Pain (CPRTLBP)
Chronic low back pain (CLBP) represents one of the leading causes of long-term disability among adults and places a substantial strain on healthcare systems globally.
- Trial name
- CPRTLBP (NCT07399145)
- Testing
- Prolotherapy, Balneotherapy plus Physiotherapy, Physiotherapy
- Where
- Romania
- Volunteers
- 84 people
- Sponsor
- Balnear and Rehabilitation Sanatorium Techirghiol
Plantar Fascitis
Evaluation of the Efficacy of Prolotherapy Treatment in Patients With Plantar Fasciitis: a Randomized Double-blind Study
Plantar fasciitis is the most common cause of heel pain and it is diagnosed by clinically. Resting, stretching exercises, weight loss, nonsteroidal anti-inflammatory drugs and physical therapy methods are used in the treatment.
- Trial name
- NCT03731897
- Testing
- 5 cc 30% dextrose + 4 cc salin + 1cc 2% lidocaine., 9 cc salin + 1cc 2% lidocaine.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Education and Research Hospital
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01617356
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 SW/0.2% lidocaine
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Frusso, Ricardo, M.D.