Clinical trials: Prolotherapy
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01706172
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 Sterile water /0.2% lidocaine
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chisel Peak Medical Clinic
Prolotherapy
Combined Effect of Prolotherapy and Personalized Physical Activity on Knee Osteoarthritis Progression
The aim of this clinical trial is to assess whether prolotherapy combined with personal physical activity is effective in managing pain (measured using the VAS and WOMAC scales) and improving the quality of life in participants…
- Trial name
- NCT07355712
- Testing
- Prolotherapy Only, Prolotherapy, Personalized Physical Activity Program
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Gadjah Mada University
Chronic Plantar Fasciitis
Chronic Plantar Fasciitis: Which is More Effective? Prolotherapy/Extracorporeal Shock Wave Therapy?
The primary objective of this prospective study was to compare the effects of ESWT (extracorporeal shock wave therapy ) and prolotherapy on pain and foot function in patients with chronic plantar fasciitis.
- Trial name
- NCT06712329
- Testing
- extracorporeal shock wave therapy, Prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Coccydynia
Landmark-Guided Dextrose Prolotherapy for Coccydynia: A Retrospective Study
Coccydynia is a musculoskeletal pain condition that can lead to chronic pain and functional impairment, significantly affecting quality of life.
- Trial name
- NCT07564362
- Testing
- Dextrose prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Tennis Elbow
Efficacy of Injection Therapy for Lateral Epicondylosis
While evidence does not identify any conventional therapy as definitive for chronic lateral epicondylosis (CLE, tennis elbow), basic science and limited pilot level trials support rigorous assessment of prolotherapy (PrT) and…
- Trial name
- NCT01476605
- Testing
- Dextrose prolotherapy, PrT-DMS, Platelet Rich Plasma injection
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Partial-Thickness Rotator Cuff Tear
Injection Therapies for Partial Rotator Cuff Tears
This completed study compared four injection treatments in patients with painful partial tears of the rotator cuff, the tendons that help move and stabilize the shoulder.
- Trial name
- NCT07871695
- Testing
- Autologous Platelet-Rich Plasma (PRP), Dextrose 15%, Betamethasone Sodium Phosphate and Betamethasone Acetate
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Rehabilitation, Pain, Shoulder
Precision Medicine for Sng/Pain Control
Patients have different response to different treatment modalities, and sore/pain medicine is no exception. In our experience, low-level laser (LLL), ultrasound, and prolotherapy can reduce sore /pain through different genetic…
- Conditions
- Rehabilitation, Pain, Shoulder, Pain, Chronic
- Trial name
- SNG (NCT05154695)
- Testing
- LASER, A.therapeutic ultrasound group, B.prolotherapy group
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
The Aim of This Research is to Investigate the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Chronic Knee Pain
Examining the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Knee Pain
92 patients with a diagnosis of primary knee pain of unknown cause followed at the family medicine outpatient clinic and who met our exclusion criteria were invited to the study.
- Trial name
- NCT06345222
- Testing
- Prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Lateral Epicondylitis, Tennis Elbow
Injection Therapy in Patients With Lateral Epicondylitis
Lateral epicondylitis is a painful enthesopathy of the common extensor tendon at the lateral part of the elbow, with a prevalence of 1-3 % in the general population.
- Trial name
- NCT04395417
- Testing
- Hyaluronic Acid, Prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Knee Osteoarthritis, Platelet-rich Plasma (PRP)
Comparison of the Therapeutic Effects of Lyophilized Platelet-rich Plasma Lysate and Dextrose Prolotherapy in Knee Osteoarthritis
The goal of this clinical trial is to compare the therapeutic effects of lyophilized platelet-rich plasma lysate and dextrose prolotherapy in patients with knee osteoarthritis (OA).
- Trial name
- NCT07875543
- Testing
- Lyophilized Platelet-rich Plasma Lysate, Dextrose Prolotherapy
- Where
- Taiwan
- Volunteers
- 39 people
- Sponsor
- Taichung Veterans General Hospital
Sacro Iliac Joint Pain, Low Back Pain
Effectiveness Of Alcohol Addition In Ultrasound-Guided Periarticular Sacroiliac Joint Injection
The aim of this work is to evaluate the efficacy of adding alcohol to local anesthetics and steroids to provide pain relief in patients with sacroiliac joint pain.
- Conditions
- Sacro Iliac Joint Pain, Low Back Pain, Alcohol Induced Neurolysis
- Trial name
- NCT07151027
- Testing
- sacroiliac joint injection
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Fayoum University
Hemiplegic Shoulder Pain, Stroke
The Effects of 15% Dextrose Solution on Pain and Range of Motion in the Hemiplegic Shoulder
This study aims to investigate the effects of 15% dextrose solution on pain and range of motion in patients aged 40 to 75 years who have experienced a stroke and suffering from hemiplegic shoulder pain
- Trial name
- NCT06988228
- Testing
- 15% Dextrose Injection, izotonic saline injection
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Anterior Disk Displacement TMJ
Comparative Efficacy of Prolotherapy and Dry Needling in Management of ADD
Pain and trismus caused by Anterior disc displacement ADD of temporomandibular joint (TMJ) are one of the prime concerns for the patients.
- Trial name
- NCT04319406
- Testing
- Prolotherapy, Dry needling
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Knee Osteoarthritis
Effects of Steroid, Dextrose Prolotherapy, and Platelet-Rich Plasma Injections in Knee Joint OA Patients
The novelty of thisstudy lies in its comparative assessment of three latest intra-articular injection therapies including steroid injections, dextrose prolotherapy, and PRP, for knee OA associated impairments, with a focus on…
- Trial name
- NCT07243392
- Testing
- Intra articular steroid injection, Intra articular PRP, Intra articular dextrose prolotherapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Lincoln University College
Rehabilitation, Pain, Shoulder
Precision Medicine for Nociception, Sngception and Proprioception.
Precision medicine is defined as "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person" by the Precision Medicine…
- Conditions
- Rehabilitation, Pain, Shoulder, Pain, Chronic, Idiopathic Scoliosis
- Trial name
- NCT06161038
- Testing
- LASER, Ultrasound, Prolotherapy
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthritis, Obesity
HDP vs NS Intra-articular Injection Among KOA With Obese Patient
The aim of this randomized controlled trial study was to compare the effect of intra-articular injection of Hypertonic Dextrose Prolotherapy (HDP) with Normal Saline (NS) in the clinical improvement of knee osteoarthritis (KOA)…
- Trial name
- NCT05966948
- Testing
- Dextrose Solution, Normal Saline
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Rumah Sakit Umum Daerah Haji Provinsi Jawa Timur, Indonesia
Obstructive Sleep Apnea
Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea
This study was conducted on 26 patients with obstructive sleep apnea. The patients were divided randomly and equally into two equal groups.
- Trial name
- NCT06427161
- Testing
- LLLT application, dextrose injection
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Mansoura University
Osteoarthritis
Joint Injections for Osteoarthritic Knee Pain
The purpose of this study is to determine whether prolotherapy (PrT), a therapy based on injection of a sugar solution in and around the knee, can decrease pain and disability from knee osteoarthritis (OA).
- Trial name
- NCT00085722
- Testing
- Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of Wisconsin, Madison
Myofascial Pain Syndrome of Neck
Comparison of the Efficacy of Prolotherapy Injection Therapy & Local Anesthetic Injection Therapy.
Myofascial pain syndrome is a disease characterized by pain over the trigger point in a taut muscle band. After the correct diagnosis is made, many treatment methods can be applied.
- Trial name
- NCT05239091
- Testing
- Dextrose solution, Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Rotator Cuff Tendinosis, Supraspinatus Strain
The Effects of Platelet-Rich Plasma Versus Prolotherapy On Rotator Cuff Tendinopathy: A Randomized Controlled Trial.
Rotator cuff tendinopathy is the common cause of shoulder pain in the working-age group and the elderly (1). The condition reported takes an average of 10 months or longer to recover.
- Conditions
- Rotator Cuff Tendinosis, Supraspinatus Strain, PRP
- Trial name
- NCT04640662
- Testing
- Platelet-Rich Plasma, Prolotherapy
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya