Clinical trials: Prone Positioning
Acute Respiratory Distress Syndrome (ARDS), Hypoxemia
Early Prone Positioning and Clinical Outcomes in Non-Intubated Acute Respiratory Distress Syndrome (ARDS) Patients
This study aimed to evaluate the effectiveness of early prone positioning in improving clinical outcomes among non-intubated patients with Acute Respiratory Distress Syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Hypoxemia, Respiratory Failure, Non-Intubated Patients
- Trial name
- EPP-ARDS (NCT07133022)
- Testing
- Early Prone Positioning Protocol, Standard ICU Care
- Where
- Palestinian Territories
- Volunteers
- 100 people
- Sponsor
- Loai Muawiah Zabin
Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter in Craniosynostosis
Changes of optic nerve sheath diameter after position changes
- Trial name
- ONSD (NCT03131245)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
ARDS, Human
Prone-Supine Study II: The Effect of Prone Positioning for Patients Affected by Acute Respiratory Distress Syndrome
The purpose of this study is to determine whether prone positioning is effective in improving survival in patients affected by acute respiratory distress syndrome (ARDS).
- Trial name
- NCT00159939
- Testing
- prone positioning
- Where
- 17 sites in Italy
- Volunteers
- 344 people
- Sponsor
- Policlinico Hospital
Fixation Device; Complications
Comparison of Endotracheal Tube Fixation Methods in Prone Position
In particular, prone position surgeries risk potentially life-threatening ET tube dislocation. Failure to place the plaster used for ET tube fixation correctly and adequately in this position may contaminate the patch with body…
- Trial name
- NCT05643053
- Testing
- thomas fixation, elastic band, normal fixation adhesive tape
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Breast Cancer
SuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy)
A randomised, two-arm, non-blinded crossover study investigating the impact of treatment position (prone versus supine) upon reproducibility of tumour bed position in patients undergoing breast radiotherapy following excision of…
- Trial name
- SuPr (NCT01001728)
- Testing
- Imaging investigations (with radiation)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Anesthesia
The Effect of Pressure-controlled Ventilation-volume Guaranteed Mode
The anesthetized patient is turned to the prone position during lumbar spine surgery. The dynamic compliance of lung usually decreases and peak airway pressure increases during the surgery.
- Trial name
- NCT03571854
- Testing
- Group PCV-VG, Group VCV
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Hallym University Medical Center
Prone Position, Donors
Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial
Background and justification: In Argentina, 9,650 people are on the organ transplant waiting list, including 290 who require a lung transplant.
- Conditions
- Prone Position, Donors, Lung Procurement, Tissue Donors
- Trial name
- PRODONAR (NCT07251777)
- Testing
- Prone position
- Where
- Argentina
- Volunteers
- 254 people
- Sponsor
- Hospital de Alta Complejidad del Bicentenario Esteban Echeverría
Respiratory Failure With Hypoxia, Respiratory Failure Without Hypercapnia
Prone Positioning During High Flow Oxygen Therapy in Acute Hypoxemic Respiratory Failure
Background High-flow nasal cannula (NHF) are a promising tool for administering oxygen to critically ill patients with high respiratory demand.
- Trial name
- Optiprone (NCT03095300)
- Testing
- Prone position
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Catholic University of the Sacred Heart
COVID-19, Respiratory Failure
Characteristics and Outcomes of Patients With COVID-19 Treated With HFNO and Prone Positioning
A subset of patients with COVID-19 develops acute respiratory failure and acute respiratory distress syndrome (ARDS) (1). The use of invasive mechanical ventilation for the treatment of these conditions is associated with high…
- Conditions
- COVID-19, Respiratory Failure, Prone Position, Endotracheal Intubation
- Trial name
- AW-PP_Covid (NCT05178212)
- Where
- Argentina
- Volunteers
- 600 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Kidney Stone
Modified Supine vs Prone Position Pnl
perform a comparative randomized trial comparing the efficacy and safety of percutaneous nephrolithotomy (PCNL) in the prone and modified supine positions in management of complex renal stones
- Trial name
- NCT05379894
- Testing
- Percutaneous nephrolithotripsy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Moderate to Severe Acute Respiratory Distress Syndrome
Effects on Biotrauma of NMBAs and PP Association During ARDS
The improved survival of patients with acute respiratory distress syndrome (ARDS) over the last decades is related to the use of so-called "protective" mechanical ventilation.
- Trial name
- CURA-PRONE (NCT06212492)
- Testing
- NMBAs, Prone positioning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Enteral Nutrition, Prone Position
A Questionnaire Survey on Cognition of Enteral Nutrition Implementation in Patients Requiring Mechanical Ventilation in Prone Position
Prone ventilation is an important treatment for respiratory failure with intractable hypoxia, and the Corona Virus Disease 2019(COVID-19 ) outbreak has further elevated the status of prone ventilation.
- Trial name
- NCT06375148
- Testing
- Enteral nutrition
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Respiratory Distress Syndrome, Acute Respiratory Failure With Hypoxia
Severe ARDS: Generating Evidence
An assessment of early management of moderate-severe ARDS in the United States, including ventilator management and use of rescue therapy.
- Conditions
- Acute Respiratory Distress Syndrome, Acute Respiratory Failure With Hypoxia, Acute Respiratory Failure
- Trial name
- SAGE (NCT03021824)
- Where
- 28 sites in United States
- Volunteers
- 2,400 people
- Sponsor
- Montefiore Medical Center
General Anesthesia
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference…
- Trial name
- NCT05275309
- Testing
- Exploration of optimal PEEP in supine and prone position
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Acute Respiratory Distress Syndrome, COVID-19 Respiratory Infection
Evaluation of the Efficiency and Complications of the Consequtive Proning in Covid -19 ICU
Thirty -one confirmed Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2 ) infected patients with Acute Respiratory Distress Syndrome (ARDS) and placed in prone position(PP) for 3 times (PP1, PP2, PP3)consecutively will…
- Trial name
- NCT05387356
- Testing
- prone position
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Kecioren Education and Training Hospital
Respiratory Distress Syndrome, Adult
Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS
This study evaluates the use of ultra-protective ventilation, where very low ventilation volumes are used, in patients with severe acute respiratory distress syndrome (ARDS) meeting criteria to nurse in the prone position.
- Trial name
- U-Protect (NCT02252094)
- Testing
- Prismalung, Ultra-protective ventilation, Conventional Lung Protective Ventilation
- Where
- 2 sites in Singapore
- Volunteers
- 8 people
- Sponsor
- National University Health System, Singapore
Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation
Machine Learning Prediction of Mortality After Prone Positioning in ARDS
Acute respiratory distress syndrome (ARDS) is a life-threatening condition with high mortality. Prone position ventilation (PPV) is an evidence-based therapy that improves oxygenation and survival in patients with moderate to…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation, Machine Learning, ICU
- Trial name
- NCT07445061
- Testing
- Prone Position Ventilation
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Zhongshan Hospital
Atelectases, Postoperative Pulmonary, Prone Position
ORI-Guided FiO₂ Titration in Prone Spine Surgery: Impact on Postoperative Atelectasis Assessed by Lung Ultrasound
Atelectasis is a frequent pulmonary complication after general anesthesia, often triggered by preoxygenation and intraoperative hyperoxia.
- Conditions
- Atelectases, Postoperative Pulmonary, Prone Position, Spine Surgery, Lung Ultrasound
- Trial name
- NCT07375173
- Testing
- Titrated Oxygen, Fixed oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Airway Management
Airway Changes in Patients Undergoing Elective Surgical Procedures in the Prone and Trendelenburg Positions
The goal of this study is to track the intraoperative changes that occur in the airways of patients undergoing 1) laparoscopic surgeries in the Trendelenburg position, and 2) spinal surgeries in the prone position, as well as the…
- Trial name
- NCT02738788
- Testing
- Intubation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Tufts Medical Center
COVID-19, Proning
Non-ventilated Prone Positioning in the COVID-19 Population
In the COVID-19 healthcare crisis, one possible treatment therapy that has generated the most discussion is that of proning, or the position in which the patient lays face down as opposed to face up for a period of time.
- Conditions
- COVID-19, Proning, Oxygenation, Length of Stay
- Trial name
- NCT05957588
- Testing
- Proning group, Control group
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Baylor St. Luke's Medical Center