Clinical trials: Prostate Biopsy
Carcinoma Prostate
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of investigation for prostate cancer in current urology practice.
- Trial name
- NCT01939743
- Testing
- Diclofenac suppository plus lidocaine gel, Lidocaine gel only
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Prostate Cancer
Immuno-molecular Approaches for Non-invasive Diagnosis of Prostate Cancer
The purpose of this study is to isolate and characterize tumor cells non-invasively from biological samples in patients with prostate cancer and demonstrate the ability to identify the presence and number of tumor cells before…
- Trial name
- PROSTA-PAP (NCT04702633)
- Testing
- Results obtained by biopsy and MRI results., Clinical data
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer XXX
The Effect of TENS on Pain, Complications and Comfort in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal Ultrasound Guided Prostate Biopsy (TRUSG-PBx) is considered the gold standard method.
- Trial name
- NCT06414421
- Testing
- Transcuten Electriacal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pain, Anxiety
Effectiveness of the Music With Structured Verbal Training During Prostate Biopsy
Transrectal ultrasound (TRUS) guided prostate biopsy is a gold standard method widely used in the diagnosis of prostate cancer. This procedure can be very painful and anxious for men.
- Conditions
- Pain, Anxiety, Satisfaction, Urological Nursing
- Trial name
- NCT04466202
- Testing
- Music with Structured Verbal Training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Prostate Cancer
Non-inferiority Randomized Controlled Trial of Cognitive Targeted Biopsy Versus Software Targeted Biopsy
This is a randomized controlled and non-inferiority trial in comparison of the cognitive fusion targeted biopsy between the software-based fusion targeted biopsy in the detection rate of clinically significant cancer in men…
- Trial name
- NCT04271527
- Testing
- cognitive fusion targeted biopsy
- Where
- China
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Prostate Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Prostate Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for prostate cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP2 (NCT05454371)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novosanis NV
Prostate Cancer
the Beijing Randomized Study Of Prostate Cancer Screening
BROPCS is a randomized trial study comparing the effectiveness of traditional systematic biopsies and bpMRI followed targeted biopsies with PSA > 4ng/ml in initial screening.
- Trial name
- BROPCS (NCT05961514)
- Testing
- Target biopsies, systemic biopsies
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Prostate
The Effect of Virtual Reality Glasses Application on Pain, Anxiety, and Patient Satisfaction
The study was conducted in a randomized controlled manner to determine the effect of applying virtual reality glasses during transrectal prostate biopsy on pain, anxiety and patient satisfaction.The study was completed with a…
- Trial name
- NCT05509114
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
PCA, Prostate Cancer
PSMA PET Combined With MRI for the Detection of PCa
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection…
- Conditions
- PCA, Prostate Cancer, Prostatic Neoplasm, PSMA PET
- Trial name
- BiPASS (NCT07052214)
- Testing
- 68Ga-PSMA-11
- Where
- 18 sites in United States, Australia
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Cancer of the Prostate
Decision Impact Trial of the ExoDx Prostate (IntelliScore)
The purpose of this research study is to investigate the utility of a validated urine test which predicts the likelihood of high grade prostate cancer on an initial prostate biopsy.
- Trial name
- NCT03235687
- Testing
- ExoDx Prostate (IntelliScore)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
Prostate Cancer XXX, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Effect of Lidocaine Gel and Cold Lidocaine Gel on Pain in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal ultrasound-guided prostate biopsy (TRUSG-PBx) is considered the current gold standard method in the diagnosis of prostate cancer.
- Trial name
- NCT06429046
- Testing
- LIDOCAINE GEL, COLD LIDOCAINE GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Prostatic Neoplasm of Uncertain Behavior
Combining High-frequency Micro-ultrasound and Multiparametric MRI Target Biopsy for Detecting Prostate Cancer
Study Goal: The purpose of this clinical trial is to determine if combining high-frequency micro-ultrasound with multiparametric MRI biopsy and a systematic biopsy can better detect clinically significant prostate cancer compared…
- Trial name
- Biopsy29 (NCT06579911)
- Testing
- High-frequency micro-ultrasound target biopsy, conventional Multiparametric MRT target biopsy
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Salzburger Landeskliniken
Aromatherapy, Prostate Cancer
Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
The study included 120 male patients who would undergo a prostate biopsy. Patients were divided into 3 groups as placebo group (n = 40), Levander group (N = 40), and Frankincense group (n = 40).
- Conditions
- Aromatherapy, Prostate Cancer, Anxiety
- Trial name
- NCT06119438
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin Training and Research Hospital
Prostatic Neoplasms, PSA
Prostate Impendance Test Project
Impedance-based analysis could provide an adequate response to the need to identify a safe and reliable tool alternative to bioptic diagnosis.
- Conditions
- Prostatic Neoplasms, PSA, Prostatic Biopsy, Impedance Test
- Trial name
- PROSIT (NCT03428087)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Prostate Cancer
Comparison of MRI Fusion Biopsy Techniques in Men With Elevated PSA and Prior Negative Prostate Biopsy
Men with elevated prostate specific antigen bloodtest and prior negative prostate biopsy have a 30-60% of harboring occult prostate cancer.
- Trial name
- NCT02138760
- Testing
- MRI UroNav fusion biopsy
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Prostate Cancer
Sulphate Accumulation in Prostate
This study evaluates whether a broccoli intervention (≥ 4 weeks) will result in differences in tissue sulphate levels in men scheduled for prostate biopsies.
- Trial name
- SAP (NCT02821728)
- Testing
- Dietary intervention, Normal diet
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Prostate Cancer, Healthy Donors
Comparative Study of Diagnostic and Prognosis Biomarkers of Prostate Cancer in Liquid Biopsy (HOPE)
Constitution of a biological collection within the framework of the establishment of a diagnostic, prognostic and active surveillance test for prostate cancer from long non-coding RNA biomarkers, in 3 cohorts of patients, with…
- Trial name
- HOPE (NCT05141383)
- Testing
- Urine sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Prostate Cancer
Study Comparing MRI/Ultrasound Fusion-guided Prostate Biopsy Versus Systematic Transrectal Ultrasound-guided Biopsy
Patients will be submitted to a multiparametric MRI examination of the prostate. Subsequently, all participants will be randomized (1:1) into both study arms.
- Trial name
- PROFUSE (NCT02450266)
- Testing
- Systematic transrectal ultrasound-guided prostate biopsy, MRI/ultrasound fusion-guided prostate biopsy
- Where
- 3 sites in Germany
- Volunteers
- 586 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Prostate Cancer
A Prospective Study to Evaluate MRI Guided Biopsy Compared With Transrectal Ultrasound Guided Biopsy of the Prostate in Men With Increased PSA Values
The purpose of this study is to determine whether MRI guided prostate biopsy achieves higher prostate cancer detection rates compared with transrectal ultrasound guided prostate biopsy in patients with increased PSA values > 4.0…
- Trial name
- NCT01553838
- Testing
- MRI guided prostate biopsy and TRUS guided biopsy
- Where
- Germany
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Prostate Cancer
Prostate Cancer Detection Rate of Targeted Biopsies With PCaVision
The primary objective is to demonstrate non-inferiority of the detection rate of clinically significant prostate cancer (csPCa) in targeted biopsies based on PCaVision imaging (PCaVision pathway) in comparison with the detection…
- Trial name
- NCT06281769
- Testing
- 3D multi-parametric ultrasound targeted biopsy pathway using PcaVision, MRI targeted biopsy pathway
- Where
- 5 sites in Netherlands
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)