Clinical trials: Prostatic Diseases
Breast Cancer, Ovarian Cancer
Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate Cancers
This study is evaluating the effect of two pre-test education methods on participants interested in genetic testing for hereditary cancer risk.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Metastatic Prostate Cancer
- Trial name
- GeneBOPP (NCT04330716)
- Testing
- Standard Genetic Counseling, Educational Video
- Where
- 6 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Neoplasms, Cancer
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
The Cancer Experience Registry®: An Online Survey Research Study to Understand the Experiences of Those Impacted By a Cancer Diagnosis. The Registry is a web-based platform to distribute cross-sectional and longitudinal surveys.
- Conditions
- Neoplasms, Cancer, Caregiver
- Trial name
- CER (NCT02333604)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Cancer Support Community, Research and Training Institute, Philadelphia
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms
Emsella for Reducing tSUI After HOLEP
This study aims to investigate the effectiveness of the Emsella chair treatments at different timepoints. Before and after the holmium laser enucleation of the prostate (HoLEP).
- Conditions
- Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
- Trial name
- NCT07580404
- Testing
- Emsella chair
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prostate Neoplasm
Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI
This study evaluates if technical improvements in MRI can be used to provide improved performance contrast-enhanced MRI as used for angiography and perfusion as well as in non-contrast MRI.
- Trial name
- NCT06315595
- Testing
- Non-Interventional Study
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
BPH With Symptomatic Lower Urinary Tract Symptoms
ProVIDE II Bridging Study
The purpose of the ProVIDE II Bridging Study is to evaluate the performance of the Generation II delivery system when deploying the ProVee expander in subjects with symptomatic urinary obstruction secondary to BPH.
- Trial name
- NCT06236802
- Testing
- ProVee device
- Where
- 8 sites in United States, Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ProVerum Medical
Prostate Cancer, Sexual Dysfunction and Infertility
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
- Trial name
- NCT01982058
- Testing
- communication intervention, counseling intervention, nutrition intervention
- Where
- 6 sites in United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Prostate Cancer
Aberrant Gene Expression Prostate Carcinoma
The goal of the study is to gain a better understanding of the molecular changes responsible for causing prostate cancer and that examination of tissue and blood samples will help in the development of improved screening and…
- Trial name
- NCT00868803
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Prostate Cancer, Sexual Dysfunctions, Psychological
Innovations in the Treatment of Sexual Health Post Prostate Cancer Treatment: Comparing Mindfulness vs. CBT
Up to 90% of men experience sexual difficulties after receiving treatment for prostate cancer (PC), which can negatively affect their intimate relationships and overall quality of life.
- Conditions
- Prostate Cancer, Sexual Dysfunctions, Psychological, Sexual Dysfunction, Physiological, Sexual Dysfunction Male
- Trial name
- INTROSPPECT (NCT03365518)
- Testing
- Cognitive Behavioural Therapy (CBT), Mindfulness-Based Therapy
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
PSA, Elevated PSA
Marker Driven Selection of Patients for Prostate Biopsy and Management
The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood and urine biomarkers is more effective…
- Conditions
- PSA, Elevated PSA, Prostate Cancer
- Trial name
- MDSelect (NCT04240327)
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Miami
Arthritis Knee, Spine Fusion
Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery
The present study is a multi-center randomized prospective non-inferiority trial. The study's primary objective is to compare the coagulation profile upon using two different TXA administration strategies: empirical TXA…
- Conditions
- Arthritis Knee, Spine Fusion, Prostate Cancer, Arthritis of Hip
- Trial name
- NCT05957822
- Testing
- TXA, TEG6
- Where
- South Korea
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Cancer of Prostate, Anxiety
Tailored, wEb-based, Psychosocial and Physical Activity Self-Management PrOgramme
Caregivers of men with prostate cancer report high physical and emotional distress, and there is an urgent need to develop cost-effective programmes to prepare them for their roles.
- Trial name
- TEMPO (NCT04304196)
- Testing
- TEMPO, Usual care
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Prostate Cancer
Preoperative PSMA PET/CT As Triage for EPLND in Patients Scheduled for RALP (PrePSMA)
Extended pelvic lymph node dissection (ePLND) is considered the gold standard for nodal staging in men with prostate cancer (PCa).
- Trial name
- PrePSMA (NCT06398613)
- Testing
- extended pelvic lymph node dissection (ePLND)
- Where
- Norway
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Cancer, Colorectal Cancer
Michigan Genetic Hereditary Testing (MiGHT)
The primary purpose of this study is to compare three interventions, two experimental and one standard of care (usual care), to see if the experimental interventions will increase the likelihood of a participant obtaining…
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- MiGHT (NCT05162846)
- Testing
- Publicly available genetic testing resources, Virtual genetics navigator, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Prostate Infection, Prostate Disease
The Relationship Between Serum PSA Levels and WBC, Delta Neutrophil Index (DNI) and Other Hematological Parameters
Purpose: To find the correlation between hemogram parameters and Delta Neutrophil Index(DNI) and Serum PSA in patients presenting with the diagnosis of acute prostatitis.
- Conditions
- Prostate Infection, Prostate Disease, Prostate Cancer
- Trial name
- NCT05399940
- Testing
- Serum PSA,Delta Neutrophil Index(DNI),WBC
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Androgen Deprivation Therapy, Prostate Cancer
Contributions to Hypertension With Androgen Deprivation Therapy
This study plans to learn more about contributors to high blood pressure in men who undergo androgen deprivation therapy (ADT) to treat prostate cancer.
- Conditions
- Androgen Deprivation Therapy, Prostate Cancer, Hypertension, Autonomic Dysfunction
- Trial name
- ARCH (NCT05700903)
- Testing
- Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prostate Cancer, Hirsutism
Relative Bioavailability Study of Bicalutamide 50 mg Tablet and Casodex Following a 50 mg Dose in Healthy Subjects Under Fed Conditions
The purpose of this study is to demonstrate the relative bioavailability of Bicalutamide 50 mg tablet and Casodex following a 50 mg dose in healthy subjects under fed conditions.
- Trial name
- NCT00960310
- Testing
- Bicalutamide 50 mg Film-Coated Tablets (Sandoz Inc., USA), Bicalutamide 50 mg Film-Coated Tablets (Casodex) (Astrazeneca Pharmaceutical LP, USA)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sandoz
Ejaculation Abnormal, BPH With Urinary Obstruction
Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT
To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group.
- Conditions
- Ejaculation Abnormal, BPH With Urinary Obstruction, Prostatic Hyperplasia, Prostate Disease
- Trial name
- EPPROSTATECT (NCT03589196)
- Testing
- Ejaculation Preserving Photoselective Vaporization, Ejaculation Preserving Plasma Kinetic Vaporization, Ejaculation Preserving Transurethral Resection Of The Prostate
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostate Cancer
Problem Solving Therapy for Prostate Cancer Spousal Caregivers
Problem-solving therapy programs have been shown to be effective among parents of children diagnosed with cancer. Efforts have been made to apply this same strategy to spouses/significant others of men diagnosed with prostate…
- Trial name
- NCT02085096
- Testing
- Problem-Solving Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Benign Prostate Hyperplasia, Healthy
Safety and Pharmacokinetic Characteristics of DKF-313
This is a randomized, open-label, single-dose, 2-treatment, 2-way, 2-period crossover study to evaluate the safety and the pharmacokinetic characteristics of DKF-313 (dutasteride and tadalafil) in healthy male volunteers.
- Trial name
- NCT02352311
- Testing
- DKF-313, AVODART, CIALIS
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Dongkook Pharmaceutical Co., Ltd.
Prostatic Hyperplasia
The Effect of Using a Motivation Card on Pain and Number of Walking Steps After Prostate Surgery
The purpose of this clinical study is to evaluate the effect of using motivational cards on pain and step counts in patients who underwent open prostate surgery due to benign prostatic hyperplasia.The main hypotheses are: H1…
- Trial name
- NCT06699563
- Testing
- Mobilization Motivation Card
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University