Clinical trials: Prostheses and Implants, active
Dental Implant
Safety and Effectiveness of DSP Dental Implant Systems: Prospective Study Multicenter Involving Real-world Data
Studies on facial trauma are essential to establish an appropriate treatment approach, assess the ability to restore functions and seek ways of prevention.
- Trial name
- NCT05986669
- Where
- 2 sites in Brazil
- Volunteers
- 700 people
- Sponsor
- DSP Industrial Ltda
Prosthetic Joint Infection, Debridement With Prosthesis Retention
Antibiotic-coated Braided Suture Study
The purpose of this study is to evaluate whether the use of antibiotic-coated (triclosan) braided sutures is non-inferior or potentially superior to standard monofilament sutures in patients with prosthetic joint infections…
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
- Trial name
- NCT07322289
- Testing
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Miami
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Amputation, Prostheses and Implants
Regenerative Peripheral Nerve Interface for Control of Lower Limb Prostheses
Individuals with an above-knee lower limb amputation are known to walk more slowly, expend more energy, have a greater risk of falling, and have reduced quality of life compared to individuals without amputation and those with…
- Trial name
- NCT06275282
- Testing
- Intramuscular electrodes
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Prosthesis User
Clinical Performance of 3D-Printed Resin and Zirconia Implant Restorations
This randomized controlled clinical trial evaluates the clinical performance of 3D-printed resin restorations compared with milled monolithic zirconia in implant-supported single crowns and short-span fixed partial dentures…
- Trial name
- NCT07522671
- Testing
- 3D-Printed Resin Restoration (CROWNTEC)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb
Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
This study supports Spanish data collection and analysis on Periprosthetic and Peri-implant fractures of the upper and lower limb. Treatment and clinical management of this fractures are complex and goes along with complications.
- Conditions
- Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb, Periprosthetic Fractures, Peri-implant Fracture
- Trial name
- PIPPAS (NCT04663893)
- Where
- 7 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Tooth Loss and Rehabilitation With Telescopic Crown Prostheses
Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis
This study aims to compare the clinical and patient satisfaction outcomes of rigid versus non-rigid digitally fabricated telescopic double crown prostheses supported by teeth and implants.
- Trial name
- NCT07682623
- Testing
- Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Complication, Prosthesis Durability
SEBBIN Silicone Gel-filled Testicular Implants
This study is part of the clinical evaluation of SEBBIN silicone gel-filled testicular implants, included in the technical file of the device.
- Trial name
- NCT04968470
- Where
- 2 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Groupe SEBBIN
Glenohumeral Osteoarthritis
Poly vs Hybrid Glenoid in Stemless aTSA
Participants are randomized 1:1 to receive either a cemented all-polyethylene pegged glenoid or a hybrid trabecular titanium-pegged glenoid during anatomic total shoulder arthroplasty.
- Trial name
- Poly vs hybrid (NCT07520721)
- Testing
- Anatomic total shoulder arthroplasty with cemented all-polyethylene pegged glenoid, Anatomic total shoulder arthroplasty with hybrid trabecular titanium central-peg glenoid
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- Spaarne Gasthuis
Edentulism, Biological Aging
Biological Aging Following Full-Arch Implant-Supported Fixed Rehabilitation in Edentulous Patients
This study aims to investigate the association between full-arch implant-supported fixed dental rehabilitation and changes in biological aging among adults with complete tooth loss (edentulism).
- Trial name
- NCT07890753
- Testing
- Full-Arch Implant-Supported Fixed Dental Rehabilitation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Junyu Shi
Peri-Implant Health
Plaque and Bleeding on Probing Around Implants Supporting Fixed Full-Arch Dental Prostheses
This observational study examines plaque, hard deposits (calculus), and gum bleeding around dental implants supporting fixed full-arch dental prostheses.
- Trial name
- NCT07898956
- Testing
- Prosthetic Maintenance History
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Bone Loss, Hip Prosthesis Infection
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
In this prospective multicenter study, a population of adult individuals consecutively treated for revision hips, requiring a custom-made acetabular implant for non-oncological reasons, will be included.
- Conditions
- Bone Loss, Hip Prosthesis Infection, Arthroplasty Complications
- Trial name
- CustomPN (NCT06527664)
- Testing
- custom-made acetabular implant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Amputation of Upper Limb
A Multicenter, Multinational, Cohort Long-term Post-market Clinical Follow-up (PMCF) of the Safety and Efficacy of the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant System When Used for Transhumeral Implantation in Amputee Patients
This non-interventional clinical investigation is initiated for the purpose of long-term Post-Market Clinical Follow-up (PMCF) and the follow-up time of patients is expected to span from 6 months to >20 years in function.
- Trial name
- ReTHro (NCT06753110)
- Testing
- OPRA transhumeral
- Where
- 6 sites in Australia, Austria and 3 more
- Volunteers
- 70 people
- Sponsor
- Integrum
Failure, Prosthesis, Dental Prosthesis, Implant-Supported
Clinical Performance of All-on-4 PEEK and Conventional Prostheses
The all-on-4 treatment approach for completely edentulous mandible is a proven concept. However, there are still issues regarding the use of metal substructure to support the prostheses such as allergy, metallic taste, and…
- Conditions
- Failure, Prosthesis, Dental Prosthesis, Implant-Supported, Survival, Prosthesis, Complete Edentulism
- Trial name
- NCT06388395
- Testing
- Accuracy of full-arch surgical guides, Survival and complications of the prostheses, Survival and complications of the implants
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Edentulism, Complete Maxillary Edentulism
Jaw Tracking Impact on Occlusion and Patient Outcomes in Maxillary Implant Restorations
This randomized clinical trial aims to evaluate the effect of integrating digital jaw tracking into the workflow for fabrication of full-arch maxillary implant-supported screw-retained restorations.
- Trial name
- NCT07693946
- Testing
- Conventional Prosthetic Workflow, Digital Jaw-Tracking Workflow
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Complete Edentulism
Microbial Adhesion and Peri-Implant Tissue Health in All-on-Four Hybrid Prostheses Supported by Zantex or Zirconia Frameworks
This study compares two materials (Zantex and Zirconia) used to make fixed full-arch dental prostheses supported by four dental implants (the "All-on-Four" technique) in patients who have no natural teeth in the lower jaw.
- Trial name
- NCT07811661
- Testing
- Zirconia Framework, Zantex Framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Kafrelsheikh University
Dental Implants, Dental Prosthesis, Implant-Supported
Clinical Evaluation of a Hyperbolic Paraboloid Triple-Abutment on Morse Taper Dental Implants
This prospective clinical study aims to evaluate the clinical and radiographic outcomes of a novel triple-abutment system with hyperbolic paraboloid geometry installed on Morse taper dental implants.
- Trial name
- NCT07310979
- Testing
- Triple-Abutment System with Hyperbolic Paraboloid Geometry
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Abdominal Aortic Aneurysms (AAA)
Use of Artificial Intelligence to Predict Complications Following Abdominal Aortic Surgery
Abdominal aortic aneurysm, a condition characterised by an increase in the diameter of the aorta, can be treated either surgically or endovascularly.
- Trial name
- AORTAPREDICT (NCT06884397)
- Testing
- Abdominal aortic endoprosthesis
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Completely Edentulous, Implant Assesment
Fully Versus Partially Guided Implants Placement: Measurement of Accuracy of Implant Position and Passivity of Superstructures.
compare fully versus partially guided all on four implants placement immediately loaded by maxillary and mandibular screw retained overdentures: A radiographic and photogrammetric measurement of accuracy of implant position and…
- Trial name
- NCT07174791
- Testing
- cone beam computed tomography, photogrammetric scan using elite scanner (shining 3d)
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Peri-Implant Health, Implant Complication
Influence of Zirconia Abutments on Peri-Implant Tissues in Single-Tooth Restorations
Objectives: To compare the influence of pre-fabricated titanium abutments and customized milled zirconia abutments on implant biocompatibility and the peri-implant region, as well as on radiographic bone loss and oral…
- Conditions
- Peri-Implant Health, Implant Complication, Prosthesis and Implants
- Trial name
- NCT07456163
- Testing
- Pre-fabricated standardized titanium abutments, Customized anatomical zirconia abutments
- Where
- Brazil
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil