Clinical trials: Prosthetic
Amputation Stump
Computational Design, Fabrication, and Evaluation of Optimized Patient-Specific Transtibial Prosthetic Sockets
The overall goal of this study is to further develop and clinically assess a computational and data-driven design and manufacturing framework for mechanical interfaces that quantitatively produces transtibial prosthetic sockets…
- Trial name
- NCT03544853
- Testing
- Prosthetic socket for transtibial amputee
- Where
- 2 sites in United States, Mexico
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Prosthesis User, Amputation
Prosthetic Limb Movement Feedback for Upper and Lower Extremity Amputees
To assess the functional characteristics and utility of upper and lower limb prosthetic devices (advanced bionic and current clinical standard-of-care) that incorporate physiologically relevant touch and/or movement feedback.
- Trial name
- NCT03135847
- Testing
- Tactor
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Amputation
Stability and 3D Motion Study of an Experimental Prosthetic Foot
The investigators are currently verifying early data showing that the K3 Promoter prosthetic foot affects walking efficiency or stability in transtibial, unilateral amputees when compared to their current prostheses.
- Trial name
- NCT00968292
- Testing
- Experimental prosthetics foot (K3 Promoter)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tensegrity Prosthetics
Dental Implant, Prosthetic Abutment
One-time Abutment Placement Versus 4 Times Abutment Removal Around Dental Implants
Introduction: the repeated connection and disconnection of healing abutments during dental implants´ osseointegration has been associated with significant increased peri-implant bone loss, when compared with placing the final…
- Trial name
- NCT05711147
- Testing
- Abutment removal, Placement of definitive abutment
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Osteoarthritis, Hip, Arthropathy of Hip
Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
The aim of this project is to investigate prosthesis fixation in the bone, respectively cemented and uncemented operation method of Avantage® dual-mobility acetabular cup in elderly patients, wear of the plastic in dual-mobility…
- Trial name
- NCT02404727
- Testing
- cup fixation, Avantage® Cup
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lower Limb Amputation, Older Adults
Study of WiiFit to Enhance Walking in Older Adult Amputees
WiiNWALK is a 4 week physical activity, with the intervention of a WiiFit, targeted to improve walking capacity in individuals with either a unilateral below-knee or above-knee amputation.
- Trial name
- WiiNWalk (NCT01942798)
- Testing
- Nintendo Wii, Wii Big Brain Academy Degree program
- Where
- 5 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Completely Edentulous
Prosthetic Maintenance of Two Implant-Retained Overdentures Reinforced With PEKK Versus Co-Cr Frameworks
The goal of this randomized clinical trial is to compare and assess the prosthetic maintenance of two implant-retained mandibular overdentures reinforced with PEKK and Co-Cr frameworks after twelve months.
- Trial name
- NCT06219811
- Testing
- Two implant -retained overdenture reinforced with Co-Cr framework, Two implant -retained overdenture reinforced with PEEK framework
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Amputation of Upper Limb Below Elbow, Prosthesis User
Effect of Motor Imagery Ability on Functionality and Proprioception in Amputees Using Myoelectric Prostheses"
The purpose of this study is to evaluate the motor imagery ability in transradial amputees using myoelectric prosthesis, compare it with the control group and investigate its effect on functionality and proprioception.
- Trial name
- NCT06541379
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medipol University
Orthopedic Disorder, Hip Arthropathy
Iron and Vitamin Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation plus cofactors in reducing the prevalence of preoperative anemia in a cohort of 60 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04880499
- Testing
- Iron plus folic acid, vitamin B2, B6, B12, C, and E
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Crown Lengthening
Influence of Restorative Timing on Crown Lengthening Outcome.
Setting the restorative margins for teeth with short clinical crowns is challenging and crown lengthening surgery (CLS) is often necessary.
- Trial name
- NCT03947658
- Testing
- Surgical crown lengthening
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peri-implantitis
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by…
- Trial name
- NCT07391202
- Testing
- Non-Surgical Peri-Implant Therapy without Crown, Non-Surgical Peri-Implant Therapy with Crown
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Diabetes Mellitus, Leg Injuries
Prosthetic Components and Stability in Amputee Gait
The biomechanics of changing direction while walking has been largely neglected despite its relevancy to functional mobility. In addition, an increased risk of injury can be associated with turning due to a decrease in stability.
- Conditions
- Diabetes Mellitus, Leg Injuries, Traumatic Amputation
- Trial name
- NCT00167778
- Testing
- Transverse plane rotation adaptor pylon, Rigid pylon
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Poor Drug Response
The Prevalence of Sub Optimal Anti Coagulation
A study on warfarin administration to show whether noncompliance of the patient will affect our target (INR) during therapy or not beside its drug and dietary interactions.
- Trial name
- NCT03485300
- Testing
- Liver and kidney function tests for patients with chronic liver or kidney diseases, Non compliance of the patient, Drug or food interactions
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Prosthetic
Sensory Feedback for Touch and Proprioception With Prosthetic Limbs
Upper limb amputation is a devastating injury that leaves many thousands of typically young and active individuals in the US to rely on artificial arms and hands to help restore their lost function.
- Trial name
- NCT02189031
- Testing
- Tactor array, Bypass Tactor
- Where
- 4 sites in United States, Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Prosthesis Survival
Prosthetic Management of All on Four Versus All on Six to Rehabilitate Completely Edentulous Maxillary Ridge Opposed by Natural Teeth
the aim of the study to compare the anterior maxillary bone index changes for patient rehabilitated with implant supported fixed prosthesis opposed by natural teeth
- Trial name
- NCT06114069
- Testing
- implant supported maxillary fixed prosthesis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Complications Implants
Maintenance Assessment For Implant Fixed Complete Dentures With Implant Overdentures. A RCT
There are two types of complications in implant prosthesis: biologic and prosthetic . Biologic complications refer to disorders in implant function that disturb the supporting peri-implant tissues resulting in mucositis or…
- Trial name
- NCT05815589
- Testing
- screw retained prosthesis group
- Where
- 3 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amputation Stump
Characterization of Residual Limb Volume Changes in Transfemoral Amputees
This study quantifies residual limb volume fluctuations affecting transfemoral amputees due to the prosthesis doffing, physical activity, and testing time.
- Trial name
- NCT04709367
- Testing
- 3D optical scan
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Transfemoral Amputees
Evaluation of an Acceleration-Based Prosthetic Knee Locking Mechanism for Reducing the Risk of Falling in Transfemoral Amputees
The investigators hypothesize that a new automatic prosthetic knee locking mechanism will improve gait characteristics during an induced controlled trip and reduce fear of falling.
- Trial name
- NCT01982721
- Testing
- Locking mechanism for prosthetic knee
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization