Clinical trials: Protein Restriction
Anorexia Nervosa, Anorexia Nervosa Restricting Type
Novel Targetable BIOmarkers in ANorexia NervosA
The overall aim of this present study is to evaluate Growth Differentiation Factor-15 (GDF-15) and inflammatory cytokines as a possible novel and readily treatable target for the successful therapy of Anorexia Nervosa (AN).
- Trial name
- BIOANNA (NCT05885724)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Muscle Wasting, Protein Intake
Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
Because of these anabolic properties of ketone bodies and the fact that ketone bodies prevent muscle protein breakdown for gluconeogenesis during energetic stress, ketone bodies can be a promising strategy to prevent or treat…
- Conditions
- Muscle Wasting, Protein Intake, Ketosis, Caloric Restriction
- Trial name
- NCT04744142
- Testing
- Ketone supplementation, Increased protein intake
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Overweight, Obesity
Effects of WB-EMS and Protein Supplementation on LBM Maintenance During Intended Weight Loss
The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women.
- Conditions
- Overweight, Obesity, Abdominal Obesity
- Trial name
- NCT03746977
- Testing
- Protein, Walking, WB-EMS application
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obesity
Study to Assess the Effects of High Protein Diet in Obesity, the LOWER Study
This program is carried out in a dedicated outpatient-clinic in the city of Hengelo for the evaluation and treatment of subjects with obesity.
- Trial name
- LOWER (NCT00862953)
- Testing
- Normal protein energy-restricted, High protein energy-restricted
- Where
- Netherlands
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Osteoarthritis
The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis
Patients will be randomized into the control or intervention group. Based on patient preference, the intervention group will be trained for one hour in either individual or group format on vegan diet.
- Trial name
- NCT01939262
- Testing
- Limitation of Animal Fat and Protein in the Diet, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Pregnancy Related
Effects of Snakehead Fish on IUGR and LBW Among Second and Third Trimester Women
This study uses a Randomized Controlled Trial (RCT) design, conducted on pregnant women in Yogyakarta Province, Indonesia. This study aims to observe the effects of snakehead fish prepared-meal intervention on fetal growth…
- Trial name
- NCT07005609
- Testing
- Snakehead fish meal
- Where
- Indonesia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Obesity
Effects of Short-term Energy Deficit on Muscle Protein Turnover
Weight loss through energy restriction results in the loss of both fat and muscle mass. Muscle mass is important for mobility, strength, glucose control and energy expenditure, and therefore the retention of muscle mass during…
- Trial name
- NCT02406040
- Testing
- Energy Restriction
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Mobility Limitation
Effect of Whey Protein Supplementation and Resistance Exercise on Muscle Parameters in Older Adults
This research study is looking at the effects of a whey protein nutritional supplement on changes in muscle mass, strength and physical function in response to a 6 month program of strength training exercise.
- Trial name
- NCT00635739
- Testing
- Whey protein
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tufts University
Pregnancy Related
Protein Supplementation of Snakehead Fish Cookies on Pregnant Women
This study was randomized controlled trial study whose subjects were pregnant women in Sleman District, Yogyakarta, Indonesia. The aims of this study were to make snakehead fish cookies formula which can be well accepted by…
- Trial name
- NCT04265391
- Testing
- cookies
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
FPIES, IgE Mediated Food Allergy
Quality of Life and Eating Disorders in Children With FPIES, Food Allergy or Celiac Disease
Food allergies are associated with a decrease in quality of life. Patients with FPIES often have more food avoidance than necessary. The greater the number of avoided foods, the greater the risk of eating disorders.
- Conditions
- FPIES, IgE Mediated Food Allergy, Celiac Disease
- Trial name
- QUALIM (NCT04643704)
- Where
- France
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diet, Healthy, Body Weight
Protein Restriction (PR) for Weight Loss
Prolonged dietary protein restriction has been shown to increase energy expenditure in mice simultaneously with an increase in plasma FGF21 levels.
- Trial name
- PR (NCT06263725)
- Testing
- Restricted dietary protein, Habitual diet
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Healthy
Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction
This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by that is stimulating lipolysis on expense of IGF-I production.
- Trial name
- NCT01209429
- Testing
- GH hormone infusion, 42 hour fast, 12 hour fast
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Protein Restriction, Diet
Inflammation and Protein Restriction
There is strong scientific data that supports that short-term protein restrictive diets reduce surgical stress responses. The investigators are hoping to use the information collected from the blood serum and muscle tissue of…
- Conditions
- Protein Restriction, Diet, Inflammation
- Trial name
- NCT03995979
- Testing
- 4 Day Protein Restricted Diet
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida
Glycemic Response; Satiety, Fasting, Time Restricted
Effect of a High-Protein, High-Fiber Pre-Fast Meal on Satiety and Glycemic Profiles During Fasting
This randomized crossover study investigates the effect of consuming a high-protein, high-fiber pre-fast meal on subjective satiety and glycemic responses during fasting hours in healthy adults.
- Conditions
- Glycemic Response; Satiety, Fasting, Time Restricted, Dietary Intervention, Postprandial Glucose
- Trial name
- FAST-SAT (NCT07447505)
- Testing
- High-Protein, High-Fiber Meal, Low-Protein, Low-Fiber Meal
- Where
- Saudi Arabia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- King Faisal University
Protein, Healthy
Dietary Protein Restriction and Health
The incidence of type 2 diabetes worldwide has increased significantly over the past decades, which is associated with changing dietary habits and physical inactivity.
- Conditions
- Protein, Healthy, Diet
- Trial name
- LOWPRO (NCT06267235)
- Testing
- Dietary protein restriction
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Time Restricted Feeding
Prolonged Overnight Fast, Energy Metabolism and Skeletal Muscle Anabolic Sensitivity
Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. In humans, limiting daily food intake to a narrow window (typically ~8 hours) can bring about some beneficial…
- Trial name
- NCT05420181
- Testing
- Short 10hr fast, Long 16h fast
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Insulin Resistance
Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults
This study is being done to understand the effects of calorie restriction and weight loss on muscle protein metabolism in adult men and women.
- Trial name
- NCT01497106
- Testing
- Calorie Restriction, Control (normal living)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight
Daily Protein Intake Distribution and MPS (ARCIII)
To determine whether a balanced total daily dietary protein distribution supplemented with whey protein during a weight-loss intervention will result in increased muscle protein synthesis
- Trial name
- NCT02315014
- Testing
- whey protein
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity, Metabolic Syndrome
Effects of Pre-exercise Carbohydrate Restriction Relative to Fasting on Metabolism, Appetite, and Energy Intake in Healthy Males.
This study will compare the metabolic, appetite, energy intake, and perceptual responses to a bout of exercise completed in the evening after after a low-carbohydrate lunch meal (<10% carbohydrate content / 0.2 g/kg carbohydrate…
- Trial name
- NCT05107583
- Testing
- Low-Carbohydrate Pre-Exercise Meal, High-Carbohydrate Pre-Exercise Meal, Fasted Exercise
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University