Clinical trials: Psoriasis Patients
Chronic Plaque Psoriasis
Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis
This is an exploratory, 4 arm, parallel group, placebo-controlled study comparing three doses of AIN457 to placebo. Subjects with a diagnosis of moderate to severe chronic plaque psoriasis will be randomized to receive either…
- Trial name
- NCT00770965
- Testing
- AIN457
- Where
- 5 sites in United States
- Volunteers
- 80 people
- Sponsor
- Novartis Pharmaceuticals
Severe Plaque Type Psoriasis
Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study.
Methotrexate (MTX) is considered the 'gold-standard' drug for the treatment of severe psoriasis. Health-related quality of life (HRQOL) is impaired in patients with psoriasis, more so if disease is severe.
- Trial name
- NCT02248792
- Testing
- Methotrexate
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Narayana Medical College & Hospital
Psoriasis, Psoriatic Arthritis
Psoriasis-Arthritis & Bone Program
Purpose and rationale: To define the role of IL-17 as a mediator of structural bone lesions in psoriasis patients and patients with PsA. Primary Objective is the improvement of the PsAMRIS synovitis score baseline vs. week 24.
- Trial name
- PSARTROS (NCT02483234)
- Testing
- secukinumab
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Arthritis, Psoriatic, Hand Osteoarthritis
Central Pain Mechanisms in Patients With Hand-Osteoarthritis, Psoriatic Arthritis and Healthy Controls
In this trial different parts of the pain signalling system involved in two rheumatic diseases - painful hand osteoarthritis and psoriatic arthritis, is examined.
- Trial name
- NCT03703934
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Psoriasis, Psoriatic-arthritis
PsoBest - The German Psoriasis Registry
Treatment of moderate to severe Psoriasis (Pso) and Psoriasis-Arthritis (PsA) is largely confined to systemic therapy in Germany. Systemic therapy includes conventional systemic therapy (e.g.
- Trial name
- NCT01848028
- Where
- Germany
- Volunteers
- 3,500 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Psoriatic Arthritis
Safety and Efficacy Study of Adalimumab in Patients With Active Psoriatic Arthritis (PsA)
The purpose of the study is to assess the safety and clinical efficacy of adalimumab in active psoriatic arthritis (PsA) subjects when adalimumab is added to insufficient standard therapy including patients that have failed other…
- Trial name
- STEREO (NCT00235885)
- Testing
- adalimumab
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- Abbott
Psoriasis
Evaluation of the Sensitivity and Specificity of a Novel Quality of Life Tool to Assess the Treatment Satisfaction in Psoriasis Patients
The severity of psoriasis can be influenced by a great variety of factors including extent of the disease, lesions location and impact on quality of life.
- Trial name
- PSO-TARGET (NCT04765332)
- Testing
- DLQI and PSO-TARGET QoL grid
- Where
- 27 sites in Belgium, France
- Volunteers
- 143 people
- Sponsor
- Clinact
Psoriasis
Pythagorean Self-Awareness Intervention on Psoriasis Patients.
This one-arm, pilot, non-randomized, study was conducted at the Specialized Psoriasis Unit of Andreas Syggros Hospital in Athens, Greece.
- Trial name
- PSAIPSORIASI (NCT06691763)
- Testing
- Pythagorean Self-Awareness Intervention for stress management and health promotion
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- National and Kapodistrian University of Athens
Psoriasis (PsO)
Comparison of Otezla to SFA-002 to Placebo in Plaque Psoriasis Patients
The goal of this clinical trial] is to learn if SFA002 can treat mild, moderate and severe plaque psoriasis as good or better than Otezla, compared to placebo in adult and pediatric patients.
- Trial name
- NCT06863493
- Testing
- SFA002, Otezla
- Volunteers
- 125 people
- Sponsor
- SFA Therapeutics
Psoriasis, Psoriasis (PsO)
Effects of Different Secukinumab Maintenance Regimens on Long-Term Outcomes in Patients With Psoriasis
To evaluate the long-term efficacy of two maintenance treatment patterns of secukinumab-the standard maintenance group and the non-standard maintenance group-by assessing the median time to onset and incidence of secondary…
- Trial name
- NCT07642544
- Testing
- Standard Maintenance, Non-standard Maintenance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Psoriasis
A Study of Mirikizumab in Participants With Plaque Psoriasis
This study is known as a "drug interaction study." The purpose is to learn how commonly used drugs or substances (midazolam, warfarin, dextromethorphan, omeprazole, and caffeine) and their breakdown products get into the…
- Trial name
- NCT03718884
- Testing
- Drug Cocktail, Mirikizumab
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Eli Lilly and Company
Psoriatic Arthritis
Disease Impact and Its Correlation With Disease Activity in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disorder that causes joint pain, stiffness, skin lesions, and functional disability, significantly affecting patients' quality of life.
- Trial name
- NCT07793773
- Volunteers
- 80 people
- Sponsor
- Assiut University
Psoriasis
Efficacy and Safety of Calcipotriene/Betamethasone Gel/Ointment in Psoriasis
Patients will receive either a gel containing both calcipotriene plus betamethasone or gel with no active ingredients as treatment for their scalp psoriasis for 8 weeks.
- Trial name
- NCT00279162
- Testing
- Calcipotriene/betamethasone gel and ointment
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- LEO Pharma
Psoriatic Arthritis
Medication Adherence in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic multisystemic disease requiring ordinary doctor visits and an adherence to medication. Evaluating the parameters affecting the medication adherence is essential for the efficacy of the…
- Trial name
- NCT05223062
- Testing
- Disease activity in psoriatic arthritis (DAPSA), Compliance-Questionnaire-Rheumatology (CQR), The Brief Illness Perception Questionnaire (BIPQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Psoriasis
A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Plaque Psoriasis Involving the Hands and/or Feet
This is a Phase IV randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of SC efalizumab in adult patients (18 years of age and older) with chronic moderate to severe plaque psoriasis involving…
- Trial name
- NCT00312026
- Testing
- efalizumab
- Volunteers
- 75 people
- Sponsor
- Genentech, Inc.
Nail Psoriasis, Plaque Psoriasis
Effects of Etanercept on Nail Psoriasis and Plaque Psoriasis
The purpose of this study is to evaluate if Etanercept administered at a higher initial dose provides greater improvement in nail and skin psoriasis symptoms than a regimen with a lower initial dose.
- Trial name
- NCT00581100
- Testing
- etanercept
- Volunteers
- 136 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Plaque Psoriasis
Effectiveness of Association Mometasone Furoate 0.1% and Salicylic Acid 5% Compared With Mometasone Furoate
The aims is to evaluate the efficacy and comparative isolation of the association Mometasone furoate + Salicylic Acid and the substance isolated Mometasone furoate produced by the Laboratory Glenmark Pharmaceuticals Ltd.
- Trial name
- Psoriasis (NCT01228656)
- Testing
- mometasone furoate + salicylic acid, Mometasone furoate
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
Psoriasis Vulgaris
Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Ointment in Patients With Psoriasis Vulgaris
This study will evaluate the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment compared with calcipotriol ointment in the treatment of patients with psoriasis vulgaris for a duration of 4 weeks.
- Trial name
- NCT00248456
- Testing
- Calcipotriol plus betamethasone dipropionate ointment
- Where
- China
- Volunteers
- 320 people
- Sponsor
- LEO Pharma
Psoriasis
Study of the Efficacy, Safety and Tolerability of Oral CEP-701 in Patients With Severe Psoriasis
A 12-Week, Exploratory, Open-Label, Nonrandomized, Dose-Escalation Study of the Efficacy, Safety and Tolerability of Oral CEP-701 in Patients with Severe, Recalcitrant, Plaque Type Psoriasis.
- Trial name
- NCT00236119
- Testing
- CEP-701 20mg, CEP-701 40mg, CEP-701 60mg
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- Cephalon
Noncommunicable Disease, Psoriasis
Impact of Hand Rub Placement on Patient Trust and Disease Stigma
This study aims to investigate how the physical placement of hand sanitizer in consultation rooms affects patient trust and feelings of disease stigma.
- Trial name
- NCT07552792
- Testing
- Distant placement of hand rub, Conventional placement of hand rub
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
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