Clinical trials: Psoriasis Vulgaris
Acne, Atopic Dermatitis
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa
- Trial name
- NCT05994976
- Testing
- Blood samples collection, Oral samples collection, Hair samples collection
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Psoriasis, Psoriatic Arthritis
Discovery of Arthritis in Psoriasis Patients for Early Rheumatological Referral
Rationale: Psoriasis (PsO) is a common inflammatory skin disease. Besides the skin, it is recognized that this disease can affect multiple domains such as nails, joints and entheses.
- Conditions
- Psoriasis, Psoriatic Arthritis, Psoriasis Vulgaris, Psoriatic Nail
- Trial name
- DAPPER (NCT03816917)
- Testing
- cutaneous parameters of psoriasis (exposure), comorbidity (exposure), family history (exposure)
- Where
- Netherlands
- Volunteers
- 304 people
- Sponsor
- Radboud University Medical Center
Psoriasis Vulgaris
Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe Psoriasis
This study is a prospective, single blinded, randomized, pilot study to compare the effectiveness and safety profile of oral versus subcutaneous route of administration of methotrexate in management of patients with moderate to…
- Trial name
- NCT03408756
- Testing
- methotrexate
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Psoriasis Vulgaris, Psoriasis
Impact of Non-surgical Periodontal Therapy in the Management of Plaque Psoriasis.
Both periodontitis and plaque psoriasis are non communicable chronic inflammatory diseases. They share genetic polymorphysms (IL-1, IL-6 e TNFalfa) and risk factors (smoking, diabetes, obesity), as well as a great resemblance in…
- Conditions
- Psoriasis Vulgaris, Psoriasis, Periodontitis
- Trial name
- NCT05311501
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- University of Siena
Psoriasis Vulgaris
Secukinumab Efficacy Without the Initial Loading Dose in Patients With Psoriasis
This was a retrospective, observational study. The objective of the study is investigate the efficacy and safety of secukinumab without the initial weekly loading dose in patients with chronic plaque psoriasis.
- Trial name
- NCT03828643
- Testing
- Secukinumab
- Where
- Italy
- Volunteers
- 156 people
- Sponsor
- Universita di Verona
Psoriasis Vulgaris
Therapeutic Drug Monitoring of Guselkumab in Psoriasis Patients
Biologic such as guselkumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according to a 'one dose fits all'…
- Trial name
- BIOLOPTIM-GUS (NCT04080648)
- Testing
- Venapuncture, Patient questionnaires
- Where
- 7 sites in Belgium
- Volunteers
- 79 people
- Sponsor
- University Hospital, Ghent
Psoriasis Vulgaris, Psoriasis
Immunogenetic Profiling of Goeckerman Therapy in the Treatment of Psoriasis Vulgaris
This study examines the effect of Goeckerman therapy (a combination of phototherapy and topical crude coal tar), crude coal tar alone, and phototherapy alone on the immunologic and genetic environment within psoriatic skin…
- Trial name
- NCT03662685
- Testing
- Goeckerman Therapy, Crude Coal Tar Only, Phototherapy Only
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Psoriasis Vulgaris
A Study to Assess the Pharmacokinetics, Immunogenicity and Safety of Escalating Doses of BMS-188667 Given as a Single Intravenous Infusion to Patients With Psoriasis Vulgaris
The purpose of this protocol is to determine the single-dose pharmacokinetics and immunogicity of BMS-188667 administered as a 1 hour intravenous infusion with extended pharmacokinetic sampling.
- Trial name
- NCT00277225
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Bristol-Myers Squibb
Psoriasis Vulgaris
A 12 Day Study To Evaluate A Topical Drug To Treat Plaque Psoriasis
This is a vehicle and comparator controlled Proof of Mechanism (PoM) trial to evaluate the effect on psoriasis disease activity and safety of topically applied PF 06263276 in subjects with psoriasis vulgaris.
- Trial name
- NCT02193815
- Testing
- PF06263276, Vehicle, 2%Tofacitinib Ointment
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Pfizer
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Psoriasis Vulgaris
Ultraviolet Radiation Forecasting Based Heliotherapy For Psoriasis in Bangkok, Thailand
Due to limited number of phototherapy centres and shortage of qualified phototherapy practitioners, heliotherapy has become a promising treatment alternative in Thailand where patients effortlessly receive supervised sun-bathing…
- Trial name
- NCT04740983
- Testing
- Heliotherapy (a sole sun-bathing)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Psoriasis Vulgaris
This Trial is a Randomised, Multicentre, Investigator-blind, Vehicle and Comparator-controlled, Parallel-group Trial With the Purpose of Evaluation Efficacy, Safety and Convenience of the MC2-01 Cream
This trial is a randomized, investigator-blind, multicentre, vehicle- and comparator-controlled, parallel-group trial with the purpose of evaluating the efficacy, safety and convenience of the MC2-01 cream.
- Trial name
- NCT03802344
- Testing
- MC2-01 cream, Cal/BDP combination, Vehicle
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 498 people
- Sponsor
- MC2 Therapeutics
Psoriasis Vulgaris
Oral Chinese Herbal Medicine for Psoriasis Vulgaris With Blood Stasis Syndrome
We designed this study as a multicenter, randomized, double blinded and placebo-controlled clinical trial. The aim of the study is to evaluate the clinical efficacy, safety and control of recurrence rate of psoriasis with blood…
- Trial name
- NCT03942198
- Testing
- Taodan Granules
- Where
- 5 sites in China
- Volunteers
- 216 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Psoriasis
Characterization of Cutaneous Microbiota in the Psoriasis Pathogenesis
The skin harbors a complex and dynamic microbiota constituted by numerous microorganisms that live in symbiosis with the host. The specific etiology of psoriasis is still not-well understood; nonetheless several studies…
- Trial name
- MICROBIOTA (NCT03475914)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Psoriasis Vulgaris
A Clinical Trial Evaluating Efficacy and Safety of MC2-01 Cream
This trial is a randomized, investigator-blind, multicentre, vehicle- and comparator-controlled, parallel-group trial with the purpose of evaluating efficacy, safety and convenience of the MC2-01 cream.
- Trial name
- NCT03308799
- Testing
- MC2-01 cream, Cal/BDP combination, Cream vehicle
- Where
- 3 sites in United States
- Volunteers
- 794 people
- Sponsor
- MC2 Therapeutics
Psoriasis
A Study of Ixekizumab in Chinese Participants With Psoriasis Vulgaris
The purpose of the study is to research how much ixekizumab enters the bloodstream and how long the body takes to get rid of the drug and the safety of ixekizumab and any side effects that might be associated with it.
- Trial name
- NCT03073213
- Testing
- Ixekizumab
- Where
- 3 sites in China
- Volunteers
- 32 people
- Sponsor
- Eli Lilly and Company
Psoriasis Vulgaris, Healthy
Tissue Sodium in Patients With Psoriasis
Sodium can be buffered in the skin, which mechanism is altered during aging and in certain diseases such as hypertension. High salt environment can promote autoimmunity by expanding pathogenic IL-17 producing T helper (Th17)…
- Trial name
- TSS1 (NCT04095130)
- Testing
- 23Na Magnetic resonance imaging
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Charite University, Berlin, Germany
Psoriasis Vulgaris
Topical Double-blind, Randomized, Placebo-controlled Study in Psoriasis Patients
In this study, the safety, tolerability and efficacy of DLX105 administered topically onto the psoriatic lesion of mild-to-moderate psoriasis patients will be investigated.
- Trial name
- NCT01936337
- Testing
- DLX105 Hydrogel
- Where
- 3 sites in Austria, Germany
- Volunteers
- 59 people
- Sponsor
- Delenex Therapeutics AG
Psoriasis
Photocil (Topical) for the Treatment of Psoriasis Vulgaris
Photocil is a topical drug (cream) that selectively delivers Narrow Band - Ultraviolet B (NB-UVB) therapy when exposed to sunlight.
- Trial name
- NCT01916629
- Testing
- Photocil for Psoriasis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Applied Biology, Inc.
Psoriasis
A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis
The main objective of this study is to evaluate the long-term safety of CP-690,550 in patients being treated for moderate to severe chronic plaque psoriasis.
- Trial name
- NCT01163253
- Testing
- CP-690,550
- Where
- 323 sites in United States, Argentina and 34 more
- Volunteers
- 2,867 people
- Sponsor
- Pfizer