Clinical trials: Psychiatric Disorder
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
Muscle Weakness, Bone Health
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment and falls in older adults carry an increased risk for poor health outcomes and if identified early, can be…
- Conditions
- Muscle Weakness, Bone Health, Cognitive Decline
- Trial name
- HOPE-DIET (NCT03786835)
- Testing
- Protein supplementation and regular physical activity
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Postpartum Disorder
Effects of Pilates Exercises on Postpartum
The postpartum period for the family is the period of adjustment in which a new order is established due to adding a new member to the family.
- Trial name
- NCT05397808
- Testing
- Pilates Training, breathing and relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Mood Disorder
Comparing Compliance, Tolerability, Efficacy and Adverse Events in Bipolar Tients From Valproic Acid to Depakote ER
The purpose of this study is to compare compliance, tolerability, effectiveness, and side-effects in Bipolar I and II patients switching from Valproic Acid to Depakote ER.
- Trial name
- NCT00211250
- Testing
- Valproic Acid and Depakote ER
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joliet Center for Clinical Research
Parkinson Disease, Huntington Disease
Group Drum-Based Music Therapy Intervention for Parkinson's Disease/Huntington's Disease
Participants in this study (18-89 years) with Parkinson's disease or Huntington's disease receive drum classes twice a week for 12 weeks (24 lessons).
- Trial name
- NCT05157074
- Testing
- Group Drumming Music Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Lifestyle
Effects of Tai Chi and Yoga on Flexibility, Anxiety, and Sleep Quality in Women
Healthy women aged 18-45 years with BMI <30 were randomized into two groups to receive either Tai Chi or yoga training. Both interventions were delivered for 8 weeks, 2 sessions per week, 45 minutes per session, at Bahçeşehir…
- Trial name
- NCT07480174
- Testing
- Tai Chi, Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Major Depressive Disorder, Bipolar Disorder, Mixed
Chinese Longitudinal and Systematic Study of Bioplar Disorder
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic
- Trial name
- CLASS-BD (NCT05480150)
- Testing
- Escitalopram Oxalate Tablets, Quetiapine Fumarate Tablets, Lurasidone
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy Volunteer
Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study
The goal of this study is to learn about the body's response to cannabis based products in sleep deprived people who are currently experiencing anxiety but are otherwise healthy.
- Trial name
- CANISLEEP (NCT07656350)
- Testing
- THC, CBD, THC + CBD
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Surgery, Larynx
Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty
The purpose of this study is to measure the short- and long-term voice outcome and outcome predictors of glottoplasty, cricothyroid approximation, thyroplasty, and chondrolaryngoplasty using a prospective non-randomized…
- Conditions
- Surgery, Larynx, Transgenderism, Gender Dysphoria
- Trial name
- NCT06439290
- Testing
- Phonosurgery, Mastectomy/breast augmentation
- Where
- 2 sites in Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Ghent
Neuropsychological Rehabilitation Program (VIRTRAEL/LUCCIDY), Standard Training (TAU)
The Role of Executive Functioning in Complex Post-Traumatic Stress Disorder Among Female Survivors of Intimate Partner Violence
This project aims to investigate neuropsychological alterations in women with PTSD (Post-Traumatic Stress Disorder) and complex PTSD (CPTSD), survivors of intimate partner violence (IPV), and to implement a cognitive stimulation…
- Trial name
- BELIEVE-CPTSD (NCT06706882)
- Testing
- Experimental Training: VIRTRAEL/LUCCIDY, Active Comparator: Standard Training: Reflection Group (TAU) (Andalusian Institute of Women, 2010)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Alzheimer Disease
Deep Brain Stimulation of the Pedunculopontine Nucleus for Alzheimer's Disease
Alzheimer's disease (AD) is a brain disorder that gradually impacts cognitive functions such as memory, thinking, and daily functioning.
- Trial name
- DBS-PPN-AD (NCT06936124)
- Testing
- Deep Brain Stimulation of the Pedunculopontine Nucleus
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Alzheimer Disease
Oral Fecal Microbiota Transplant Feasibility Study in Alzheimer's Disease
The goal of this study is to assess the safety and feasibility of an oral fecal microbiota transplant (FMT) intervention for Alzheimer's disease (AD).
- Trial name
- AMBITION (NCT03998423)
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Anxiety
Examining Cortisol and Alpha Amylase in a Healthy Sample of Youth and Adults
The purpose of this study is to investigate how healthy youth and adults' cortisol levels and other hormone levels relate to anxiety levels while they participate in a behavioral task called the Trier Social Stress Task.
- Trial name
- NCT02490280
- Testing
- Trier Social Stress Test
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Malocclusion, Pain
Anxiety, Pain, and Quality of Life in Orthodontic Treatment
This study was evaluated anxiety, pain, and oral health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase…
- Conditions
- Malocclusion, Pain, Anxiety, Quality of Life
- Trial name
- NCT06133296
- Testing
- Conventional fixed treatment, Clear aligner treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Tobacco Use Disorder
Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use
Smokeless tobacco (ST), which includes both chewing tobacco and snuff, has health risks associated with its use. While treatment programs that focus on stopping tobacco use may be effective, past research has shown that…
- Trial name
- NCT00218296
- Testing
- Usual Care Group, Reduction Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Leukemia, Children
Jacobson's Progressive Muscle Relaxation Technique on Children With Leukemia Undergoing Chemotherapy.
The goal of this clinical trial is to determine the effect of Jacobson's progressive muscle relaxation technique on anxiety and fatigue among children with leukemia undergoing chemotherapy.
- Conditions
- Leukemia, Children, Fatigue Related to Cancer Treatment, Anxiety
- Trial name
- JPMRT (NCT06631196)
- Testing
- Jacobson's PMRT
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Mild Traumatic Brain Injury
Deployment Related Mild Traumatic Brain Injury (mTBI)
The study will provide evidence on the long term outcomes of mTBI in service members returning from Afghanistan and Iraq. In addition, the study will provide evidence on mTBI incidence, and symptom patterns.
- Trial name
- NCT01847040
- Where
- 2 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Defense and Veterans Brain Injury Center
Anxiety, Self Esteem
Aromatherapy for Anxiety and Self-esteem: Clinical Trial
The aim of this study was to determine whether the use of Ylang Ylang essential oil through dermal application or inhalation alters the perception of anxiety and self-esteem and physiological parameters such us blood pressure and…
- Trial name
- NCT01963689
- Testing
- Intervention Group 2, Intervention Group 1, Intervention Group 3
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sleep Disturbance
Sleep Well Observation Study
Insomnia is characterized by the recurring difficulty to fall or remain asleep despite motivation and means to do so. People with insomnia also experience excessive daytime sleepiness and other cognitive impairments while they…
- Trial name
- NCT05748574
- Testing
- Sleep Well Sachet
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
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